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Sample Collection, Preparation, Rapid On-Site Evaluation, and Triage

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Abstract

The success of an FNA procedure depends on the nature of the lesion (e.g., size, location, and consistency), the skill of the aspirator, and the availability of rapid on-site evaluation. Large palpable lesions can be aspirated by a pathologist, and small deeply seated lesions are usually aspirated by the radiologist under image guidance. Usually, a 22- to 25-gauge needle is used, and two to three needle passes are made. Aspirated materials are expressed onto several glass slides and smeared out.

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Suggested Readings

  1. Caraway NP. Strategies to diagnose lymphoproliferative disorders by fine-needle aspiration by using ancillary studies. Cancer. 2005;105:432–42.

    Article  PubMed  Google Scholar 

  2. Chen YH, Gong Y. Cytopathology in the diagnosis of lymphoma. In: Nayar R, editor. Cytology in oncology. New York: Springer; 2013. p. 211–40.

    Google Scholar 

  3. Cibas ES, Ducatman BS. Cytology: diagnostic principles and clinical correlates. 2nd ed. Edinburgh/London/New York/Oxford/Philadelphia/St Luis/Sydney/Toronto: Elsevier; 2003.

    Google Scholar 

  4. DeMay RM. Practical principles of cytopathology. Chicago: American Society of Clinical Pathologists; 1999.

    Google Scholar 

  5. Gong Y. Ancillary studies on neoplastic cytologic specimens. In: Nayar R, editor. Cytology in oncology. New York: Springer; 2013. p. 13–29.

    Google Scholar 

  6. Gong Y, Caraway N, Gu J, Zaidi T, Fernandez R, Sun X, Huh YO, Katz RL. Evaluation of interphase fluorescence in situ hybridization for the t(14;18)(q32;q21) translocation in the diagnosis of follicular lymphoma on fine-needle aspirates: a comparison with flow cytometry immunophenotyping. Cancer. 2003;99:385–93.

    Article  PubMed  Google Scholar 

  7. Gong Y, Caraway N, Stewart J, Staerkel G. Metastatic ductal adenocarcinoma of the prostate: cytologic features and clinical findings. Am J Clin Pathol. 2006;126:302–9.

    Article  PubMed  Google Scholar 

  8. Gong Y, Joseph T, Sneige N. Validation of commonly used immunostains on cell-transferred cytologic specimens. Cancer. 2005;105:158–64.

    Article  PubMed  Google Scholar 

  9. Gong Y, Sneige N, Guo M, Hicks ME, Moran CA. Transthoracic fine-needle aspiration vs concurrent core needle biopsy in diagnosis of intrathoracic lesions: a retrospective comparison of diagnostic accuracy. Am J Clin Pathol. 2006;125:438–44.

    Article  PubMed  Google Scholar 

  10. Gong Y, Sun X, Michael CW, Attal S, Williamson BA, Bedrossian CW. Immunocytochemistry of serous effusion specimens: a comparison of ThinPrep vs cell block. Diagn Cytopathol. 2003;28:1–5.

    Article  PubMed  Google Scholar 

  11. Gong Y, Symmans WF, Krishnamurthy S, Patel S, Sneige N. Optimal fixation conditions for immunocytochemical analysis of estrogen receptor in cytologic specimens of breast carcinoma. Cancer. 2004;102:34–40.

    Article  CAS  PubMed  Google Scholar 

  12. Payne M, Staerkel G, Gong Y. Indeterminate diagnosis in fine-needle aspiration of the pancreas: reasons and clinical implications. Diagn Cytopathol. 2009;37:21–9.

    Article  PubMed  Google Scholar 

  13. Piao Y, Guo M, Gong Y. Diagnostic challenges of metastatic spindle cell melanoma on fine-needle aspiration specimens. Cancer. 2008;114:94–101.

    Article  PubMed  Google Scholar 

  14. Ren R, Guo M, Sneige N, Moran CA, Gong Y. Fine-needle aspiration of adrenal cortical carcinoma: cytologic spectrum and diagnostic challenges. Am J Clin Pathol. 2006;126:389–98.

    Article  PubMed  Google Scholar 

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© 2016 Springer International Publishing Switzerland

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Gong, Y. (2016). Sample Collection, Preparation, Rapid On-Site Evaluation, and Triage. In: Metastatic Neoplasms in Fine-Needle Aspiration Cytology. Springer, Cham. https://doi.org/10.1007/978-3-319-23621-6_2

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  • DOI: https://doi.org/10.1007/978-3-319-23621-6_2

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-23620-9

  • Online ISBN: 978-3-319-23621-6

  • eBook Packages: MedicineMedicine (R0)

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