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Overview of Plant Defence Systems: Lessons from Arabidopsis-Botrytis cinerea Systems Biology

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Botrytis – the Fungus, the Pathogen and its Management in Agricultural Systems

Abstract

Botrytis cinerea is an important model system for studying the necrotrophic plant pathogen lifestyle, whilst also representing one of the most economically destructive agricultural pathogens. A key challenge to understanding the pathology of this virulent fungus involves unraveling host responses. These host responses involve complex regulatory mechanisms and multiple downstream defence processes. In addition, the pathogen is capable of manipulating cellular processes in the host to favour infection. In this chapter we will present recent advances in systems biology approaches, combining high-throughput ‘omics technologies and computational/mathematical network inference techniques, which have been used to tease apart this complex host-pathogen interaction. We will also highlight novel systems approaches from other areas of plant pathology and plant science that can be applied to provide a more comprehensive understanding of plant defence against B. cinerea. We will conclude with the key challenges of understanding how both plant defence and pathogen attack are integrated, and translating knowledge from Arabidopsis to crop plants.

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Authors and Affiliations

  1. Grand Challenges in Ecosystems and the Environment, Silwood Park, Department of Life Sciences, Imperial College London, London, SL5 7PY, UK

    Oliver Windram

  2. Midlands Integrative Bioscience Training Programme, School of Life Sciences, University of Warwick, Conventry, CV4 7AL, UK

    Claire Stoker

  3. School of Life Sciences and Warwick Systems Biology Centre, University of Warwick, Conventry, CV4 7AL, UK

    Katherine Denby

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  1. Oliver Windram
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  2. Claire Stoker
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  3. Katherine Denby
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Correspondence to Katherine Denby .

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Editors and Affiliations

  1. Centre de Versailles-Grignon, INRA, Thiverval-Grignon, France

    Sabine Fillinger

  2. Dept. Plant Path. and Weed Res., ARO, Bet Dagan, Israel

    Yigal Elad

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Windram, O., Stoker, C., Denby, K. (2016). Overview of Plant Defence Systems: Lessons from Arabidopsis-Botrytis cinerea Systems Biology. In: Fillinger, S., Elad, Y. (eds) Botrytis – the Fungus, the Pathogen and its Management in Agricultural Systems. Springer, Cham. https://doi.org/10.1007/978-3-319-23371-0_17

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