Abstract
In this paper we propose a novel approach to HEp-2 cell segmentation based on the framework of verification-based multithreshold probing. Cell hypotheses are generated by binarization using hypothetic thresholds and accepted/rejected by a verification procedure. The proposed method has the nice property of combining both adaptive local thresholding and involvement of high-level knowledge. We have realized a prototype implementation using a simple rule-based verification procedure. Experimental evaluation has been performed on two public databases. It is shown that our approach outperforms a number of existing methods.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Chan, Y.K., Huang, D.C., Liu, K.C., Chen, R.T., Jiang, X.: An automatic indirect immunofluorescence cell segmentation system. Mathematical Problems in Engineering 2014, Article ID 501206 (2014)
Cheng, C.C., Hsieh, T.Y., Taur, J.S., Chen, Y.F.: An automatic segmentation and classification framework for anti-nuclear antibody images. BioMedical Engineering Online 12(SUPPL 1) (2013)
Foggia, P., Percannella, G., Sansone, C., Vento, M.: A graph-based algorithm for cluster detection. IJPRAI 22(5), 843–860 (2008)
Foggia, P., Percannella, G., Soda, P., Vento, M.: Benchmarking HEp-2 cells classification methods. IEEE Trans. Medical Imaging 32(10), 1878–1889 (2013)
Foggia, P., Percannella, G., Soda, P., Vento, M.: Special issue on the analysis and recognition of indirect immuno-fluorescence images. Pattern Recognition 47(7) (2014)
Huang, Y., Chung, C., Hsieh, T., Jao, Y.: Outline detection for the HEp-2 cells in indirect immunofluorescence images using watershed segmentation. In: IEEE Int. Conf. on Sensor Networks, Ubiquitous, and Trustworthy Computing, pp. 423–427 (2008)
Huang, Y., Jao, Y., Hsieh, T., Chung, C.: Adaptive automatic segmentation of HEp-2 cells in indirect immunofluorescence images. In: IEEE Int. Conf. on Sensor Networks, Ubiquitous, and Trustworthy Computing, pp. 418–422 (2008)
Jiang, X., Mojon, D.: Adaptive local thresholding by verification-based multithreshold probing with application to vessel detection in retinal images. IEEE Trans. Pattern Analysis and Machine Intelligence 25(1), 131–137 (2003)
Nirmaladevi, S., Lavanya, P., Kumaravel, N.: A novel segmentation method using multiresolution analysis with 3D visualization for X-ray coronary angiogram images. Journal of Medical Engineering & Technology 32(3), 235–244 (2008)
Percannella, G., Soda, P., Vento, M.: A classification-based approach to segment HEp-2 cells. In: Proc. of IEEE Int. Symposium on Computer-Based Medical Systems, pp. 1–5 (2012)
Perner, P., Perner, H., Müller, B.: Mining knowledge for HEp-2 cell image classification. Artificial Intelligence in Medicine 26(1–2), 161–173 (2002)
Soda, P., Iannello, G.: Aggregation of classifiers for staining pattern recognition in antinuclear autoantibodies analysis. IEEE Trans. Information Technology in Biomedicine 13(3), 322–329 (2009)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Jiang, X., Percannella, G., Vento, M. (2015). A Verification-Based Multithreshold Probing Approach to HEp-2 Cell Segmentation. In: Azzopardi, G., Petkov, N. (eds) Computer Analysis of Images and Patterns. CAIP 2015. Lecture Notes in Computer Science(), vol 9257. Springer, Cham. https://doi.org/10.1007/978-3-319-23117-4_23
Download citation
DOI: https://doi.org/10.1007/978-3-319-23117-4_23
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-23116-7
Online ISBN: 978-3-319-23117-4
eBook Packages: Computer ScienceComputer Science (R0)