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The Paris System for Reporting Urinary Cytology pp 13–38Cite as

Negative for High-Grade Urothelial Carcinoma (Negative)

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Abstract

All anatomic pathology diagnostic categories include one that infers that the patient has little if any risk of a significant disease. Cytologic terminology systems conform to that convention, although identifying cellular criteria that fit into that category can be challenging. The primary goal of The Paris System for Reporting Urinary Cytology (The Paris System) is to define changes that place the patient at significant risk for high-grade urothelial carcinoma (HGUC). The Paris System has adopted the philosophy that so long as a cause of cellular alterations can be identified and the cause is not life threatening, then the cellular sample belongs in the Negative for HGUC (NHGUC) category. Furthermore, since there also may be changes suggesting or indicating low-grade urothelial neoplasia (LGUN), the sample may still be placed in the Negative category, noting the additional possibility of LGUN. Certainly, if another neoplasm beside LGUN is present, that also will be indicated in the diagnostic decision for the patient.

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Author information

Authors and Affiliations

  1. Department of Pathology/Cytopathology, The Johns Hopkins University, The Johns Hopkins Hospital, 600 N. Wolfe Street, Baltimore, MD, 21287-6940, USA

    Dorothy L. Rosenthal

  2. Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT, USA

    Michael B. Cohen

  3. Department of Urology, Saga University, Saga, Japan

    Yuji Tokuda

  4. Department of Pathology, Harper University Hospital— Detroit Medical Center, Wayne State University Medical School, Detroit, MI, USA

    Hui Guan

  5. Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, MA, USA

    Christopher L. Owens

  6. Department of Pathology, Loyola University Medical Center, Maywood, IL, USA

    Eva M. Wojcik

Authors
  1. Dorothy L. Rosenthal
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  2. Michael B. Cohen
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  3. Hui Guan
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  4. Christopher L. Owens
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  5. Yuji Tokuda
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  6. Eva M. Wojcik
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Corresponding author

Correspondence to Dorothy L. Rosenthal .

Editor information

Editors and Affiliations

  1. The Johns Hopkins Hospital, The Johns Hopkins University, Baltimore, Maryland, USA

    Dorothy L. Rosenthal

  2. Department of Pathology, Loyola University Medical Center Department of Pathology, MAYWOOD, Illinois, USA

    Eva M. Wojcik

  3. Department of Pathology and Laboratory M, University of Wisconsin School of Medine Department of Pathology and Laboratory M, MADISON, Wisconsin, USA

    Daniel F.I. Kurtycz

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© 2016 Springer International Publishing Switzerland

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Rosenthal, D.L., Cohen, M.B., Guan, H., Owens, C.L., Tokuda, Y., Wojcik, E.M. (2016). Negative for High-Grade Urothelial Carcinoma (Negative). In: Rosenthal, D., Wojcik, E., Kurtycz, D. (eds) The Paris System for Reporting Urinary Cytology. Springer, Cham. https://doi.org/10.1007/978-3-319-22864-8_3

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  • DOI: https://doi.org/10.1007/978-3-319-22864-8_3

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22863-1

  • Online ISBN: 978-3-319-22864-8

  • eBook Packages: MedicineMedicine (R0)

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