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The Role of the Appleby Operation and Arterial Resection in the Multimodality Management of Borderline Resectable Pancreatic Cancer

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Book cover Multimodality Management of Borderline Resectable Pancreatic Cancer

Abstract

Most pancreatic adenocarcinomas recur systemically and tumors involving arterial structures recur rapidly even after radical resection. A safer modification of the Appleby operation has attracted the attention of pancreatic surgeons as a potential approach for radical pancreatectomy in the context of a borderline resectable pancreatic cancer of the body and tail. The modified Appleby operation, which is synonymous with a distal pancreatectomy with celiac axis en bloc resection, is feasible and safe compared with standard distal pancreatectomy. It may lead to a wider surgical margin than that associated with standard distal pancreatectomy for pancreatic body/tail carcinoma and may relieve cancer pain by removal of the celiac arterial trunk and its associated nerve plexus. The procedure may be justified at sophisticated institutions for highly selected patients.

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Authors and Affiliations

  1. Second Department of Surgery, Wakayama Medical University, Wakayama, 641-8510, Japan

    Ken-ichi Okada & Hiroki Yamaue

Authors
  1. Ken-ichi Okada
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  2. Hiroki Yamaue
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Correspondence to Hiroki Yamaue .

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Editors and Affiliations

  1. Department of Surgical Oncology, MD Anderson Cancer Center, Houston, Texas, USA

    Matthew H.G. Katz

  2. Division of Surgical Oncology, The University of Cincinnati Medical Center, Cincinnati, Ohio, USA

    Syed A. Ahmad

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Okada, Ki., Yamaue, H. (2016). The Role of the Appleby Operation and Arterial Resection in the Multimodality Management of Borderline Resectable Pancreatic Cancer. In: Katz, M., Ahmad, S. (eds) Multimodality Management of Borderline Resectable Pancreatic Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-22780-1_16

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  • DOI: https://doi.org/10.1007/978-3-319-22780-1_16

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22779-5

  • Online ISBN: 978-3-319-22780-1

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