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Home (Self) Monitoring of Blood Pressure in Clinical Trials

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Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics

Part of the book series: Clinical Hypertension and Vascular Diseases ((CHVD))

Abstract

Self-home monitoring of blood pressure by patients at home has several advantages that are particularly important in clinical hypertension research. By obtaining multiple measurements in the usual environment of each individual, home blood pressure monitoring is superior to the conventional office measurements due to its higher reproducibility and the avoidance of the white coat phenomenon, masked hypertension phenomenon, the placebo effect, and observer bias. These features improve the sensitivity and precision of clinical trials of antihypertensive drug efficacy and increase the study power or decrease the sample size required. Moreover, home blood pressure monitoring allows the investigation of additional research aspects of the blood pressure profile and behavior such as the duration of antihypertensive drug effect, morning and nocturnal hypertension, blood pressure variability, treatment-induced changes in organ damage, and cardiovascular risk. Home blood pressure tele-monitoring provides a modern and reliable solution for the unbiased evaluation of treatment-induced blood pressure changes in long-term clinical trials.

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Authors and Affiliations

  1. Third University Department of Medicine, Hypertension Center STRIDE-7, Sotiria Hospital, 152 Mesogion Avenue, Athens, 11527, Greece

    George S. Stergiou M.D. & Angeliki Ntineri M.D.

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  1. George S. Stergiou M.D.
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  2. Angeliki Ntineri M.D.
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Correspondence to George S. Stergiou M.D. .

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  1. Calhoun Cardiology Center, University of Connecticut School of Medicine, Farmington, Connecticut, USA

    William B. White

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Stergiou, G.S., Ntineri, A. (2016). Home (Self) Monitoring of Blood Pressure in Clinical Trials. In: White, W. (eds) Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics. Clinical Hypertension and Vascular Diseases. Humana Press, Cham. https://doi.org/10.1007/978-3-319-22771-9_19

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  • DOI: https://doi.org/10.1007/978-3-319-22771-9_19

  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-22770-2

  • Online ISBN: 978-3-319-22771-9

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