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Management of Choledocholithiasis in the Cirrhotic Patient

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Abstract

Endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic sphincterotomy (ES) or endoscopic papillary balloon dilation (EPBD) is the most commonly used approach for choledocholithiasis in patients with cirrhosis. If this approach fails or the patient has altered anatomy, other options include transgastric ERCP with ES or EPBD, expandable stents, and/or lithotripsy. Although cirrhotic patients have some increased risk of bleeding, there appears to be no increased risk of post-ERCP pancreatitis in these patients, and they generally do well with ERCP with ES or EPBD. Because there is some risk associated with these procedures, if suspicion is not high, it is important to confirm the presence of choledocholithiasis with imaging studies, including magnetic resonance cholangiography. Surgery is an option if endoscopic management is unsuccessful. Surgical options include laparoscopic cholecystectomy with choledochotomy, laparoscopic common bile duct exploration, and T-tube placement.

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References

  1. Buxbaum J. Modern management of common bile duct stones. Gastrointest Endosc Clin N Am. 2013;23(2):251–75. doi:10.1016/j.giec.2012.12.003.

    Article  PubMed  Google Scholar 

  2. Del Olmo JA, García F, Serra MA, Maldonado L, Rodrigo JM. Prevalence and incidence of gallstones in liver cirrhosis. Scand J Gastroenterol. 1997;32(10):1061–5.

    Article  PubMed  Google Scholar 

  3. Maggi A, Solenghi D, Panzeri A, Borroni G, Cazzaniga M, Sangiovanni A, De Fazio C, Salerno F. Prevalence and incidence of cholelithiasis in patients with liver cirrhosis. Ital J Gastroenterol Hepatol. 1997;29(4):330–5.

    PubMed  CAS  Google Scholar 

  4. Scaglione S, Kliethermes S, Cao G, Shoham D, Durazo R, Luke A, Volk ML. The epidemiology of cirrhosis in the United States: a population-based study. J Clin Gastroenterol 2015 Sep;49(8):690–6.

    Google Scholar 

  5. Ziser A, Plevak DJ, Wiesner RH, Rakela J, Offord KP, Brown DL. Morbidity and mortality in cirrhotic patients undergoing anesthesia and surgery. Anesthesiology. 1999;90(1):42–53.

    Article  PubMed  CAS  Google Scholar 

  6. Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60(8):646–9. doi:10.1002/bjs.1800600817.

    Article  PubMed  CAS  Google Scholar 

  7. Garrison RN, Cryer HM, Howard DA, et al. Clarification of risk factors for abdominal operations in patients with hepatic cirrhosis. Ann Surg. 1984;199:648–55.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  8. Mansour A, Watson W, Shayani V, et al. Abdominal operations in patients with cirrhosis: still a major surgical challenge. Surgery. 1997;122:730–5.

    Article  PubMed  CAS  Google Scholar 

  9. Sugiyama M, Atomi Y, Kuroda A, Muto T. Treatment of choledocholithiasis in patients with liver cirrhosis. Surgical treatment or endoscopic sphincterotomy? Ann Surg. 1993;218(1):68–73.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  10. Millwala F, Nguyen GC, Thuluvath PJ. Outcomes of patients with cirrhosis undergoing non-hepatic surgery: risk assessment and management. World J Gastroenterol. 2007;13(30):4056–63.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Freeman ML. Complications of endoscopic retrograde cholangiopancreatography: avoidance and management. Gastrointest Endosc Clin N Am. 2012;22(3):567–86. doi:10.1016/j.giec.2012.05.001.

    Article  PubMed  Google Scholar 

  12. Prat F, Amouyal G, Amouyal P, Pelletier G, Fritsch J, Choury AD, Buffet C, Etienne JP. Prospective controlled study of endoscopic ultrasonography and endoscopic retrograde cholangiography in patients with suspected common-bile duct lithiasis. Lancet. 1996;347(8994):75–9.

    Article  PubMed  CAS  Google Scholar 

  13. Laokpessi A, Bouillet P, Sautereau D, Cessot F, Desport JC, Le Sidaner A, Pillegand B. Value of magnetic resonance cholangiography in the preoperative diagnosis of common bile duct stones. Am J Gastroenterol. 2001;96(8):2354–9.

    Article  PubMed  CAS  Google Scholar 

  14. Parlak E, Köksal AŞ, Öztaş E, Dişibeyaz S, Ödemiş B, Yüksel M, Yıldız H, Şaşmaz N, Şahin B. Is there a safer electrosurgical current for endoscopic sphincterotomy in patients with liver cirrhosis? Wien Klin Wochenschr 2015 Jan 10.

    Google Scholar 

  15. Baron TH, Harewood GC. Endoscopic balloon dilation of the biliary sphincter compared to endoscopic biliary sphincterotomy for removal of common bile duct stones during ERCP: a metaanalysis of randomized, controlled trials. Am J Gastroenterol. 2004;99(8):1455–60.

    Article  PubMed  Google Scholar 

  16. Park DH, Kim MH, Lee SK, Lee SS, Choi JS, Song MH, Seo DW, Min Y. Endoscopic sphincterotomy vs. endoscopic papillary balloon dilation for choledocholithiasis in patients with liver cirrhosis and coagulopathy. Gastrointest Endosc. 2004;60(2):180–5.

    Article  PubMed  Google Scholar 

  17. Qiu J, Yuan H, Chen S, Wu H. Laparoscopic common bile duct exploration in cirrhotic patients with choledocholithiasis. J Clin Gastroenterol. 2015;49(2):132–6. doi:10.1097/MCG.0000000000000068.

    Article  PubMed  Google Scholar 

  18. Li DM, Zhao J, Zhao Q, Qin H, Wang B, Li RX, Zhang M, Hu JF, Yang M. Safety and efficacy of endoscopic retrograde cholangiopancreatography for common bile duct stones in liver cirrhotic patients. J Huazhong Univ Sci Technolog Med Sci. 2014;34(4):612–5. doi:10.1007/s11596-014-1325-x.

    Article  PubMed  CAS  Google Scholar 

  19. Prat F, Tennenbaum R, Ponsot P, Altman C, Pelletier G, Fritsch J, Choury AD, Bernades P, Etienne JP. Endoscopic sphincterotomy in patients with liver cirrhosis. Gastrointest Endosc. 1996;43(2 Pt 1):127–31.

    Article  PubMed  CAS  Google Scholar 

  20. Chijiiwa K, Kozaki N, Naito T, Kameoka N, Tanaka M. Treatment of choice for choledocholithiasis in patients with acute obstructive suppurative cholangitis and liver cirrhosis. Am J Surg. 1995;170(4):356–60.

    Article  PubMed  CAS  Google Scholar 

  21. Artifon EL, da Silveira EB, Aparicio D, Takada J, Baracat R, Sakai CM, Garcia RT, Teich V, Couto DS. Management of common bile duct stones in cirrhotic patients with coagulopathy: a comparison of supra-papillary puncture and standard cannulation technique. Dig Dis Sci. 2011;56(6):1904–11. doi:10.1007/s10620-011-1593-2.

    Article  PubMed  Google Scholar 

  22. Artifon EL, Kumar A, Eloubeidi MA, Chu A, Halwan B, Sakai P, Bhutani MS. Prospective randomized trial of EUS versus ERCP-guided common bile duct stone removal: an interim report (with video). Gastrointest Endosc. 2009;69(2):238–43. doi:10.1016/j.gie.2008.05.020.

    Article  PubMed  Google Scholar 

  23. Artifon EL, Paulo S, Cardillo GZ, Ishioka S. Suprapapillary needle puncture for common bile duct access: laboratory profile. Arq Gastroenterol. 2006;43(4):299–304.

    Article  PubMed  Google Scholar 

  24. Artifon EL, Hondo FY, Sakai P, Ishioka S. A new approach to the bile duct via needle puncture of the papillary roof. Endoscopy. 2005;37(11):1158.

    Article  PubMed  CAS  Google Scholar 

  25. Kawabe T, Komatsu Y, Tada M, Toda N, Ohashi M, Shiratori Y, Omata M. Endoscopic papillary balloon dilation in cirrhotic patients: removal of common bile duct stones without sphincterotomy. Endoscopy. 1996;28(8):694–8.

    Article  PubMed  CAS  Google Scholar 

  26. Garg PK, Tandon RK, Ahuja V, Makharia GK, Batra Y. Predictors of unsuccessful mechanical lithotripsy and endoscopic clearance of large bile duct stones. Gastrointest Endosc. 2004;59(6):601–5.

    Article  PubMed  Google Scholar 

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Correspondence to Sylvester M. Black M.D., Ph.D. .

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Beal, E.W., Black, S.M. (2016). Management of Choledocholithiasis in the Cirrhotic Patient. In: Hazey, J., Conwell, D., Guy, G. (eds) Multidisciplinary Management of Common Bile Duct Stones. Springer, Cham. https://doi.org/10.1007/978-3-319-22765-8_16

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  • DOI: https://doi.org/10.1007/978-3-319-22765-8_16

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22764-1

  • Online ISBN: 978-3-319-22765-8

  • eBook Packages: MedicineMedicine (R0)

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