Acute Liver Failure: Diagnosis and Management for the General Intensive Care



Acute liver failure is a rare condition, resulting from a rapid decline in hepatic function with potentially life threatening sequelae. Detailing the definitions pertinent to the syndrome, the chapter outlines the evidence behind prognostication and the identification of patients requiring intensive care and subsequent tertiary specialist input. Exploring the evidence behind current practice, this chapter allows the general intensivist quantifiable insight upon which to base management decisions both in the initial and continuing management of such complex patients.


Liver failure Encephalopathy Coagulopathy King’s College Criteria Intensive Care 

Summary of Abbreviations


Acute-on-chronic liver disease


Haemolysis, elevated liver enzymes, low platelet count


Intracranial pressure


Medicines and healthcare products regulatory agency


Positive end expiratory pressure


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Magill Department of Anaesthesia, Intensive Care Medicine and Pain ManagementChelsea and Westminster HospitalLondonUK

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