Abstract
A 22-year-old male is brought to the emergency department after sustaining a motor vehicle accident and hemorrhagic shock. The massive transfusion protocol is activated, and the patient receives two trauma packs (each trauma pack contains five units of uncrossmatched group O-negative red blood cells (RBCs), five units of AB plasma, and one unit of (any ABO type) apheresis platelets). Subsequently, a type and screen sample (ethylenediaminetetraacetic acid, EDTA anticoagulant) is submitted to the blood bank.
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Reference
Holcomb JB, Tilley BC, Baraniuk S, et al. PROPPR Study Group. Transfusion of plasma, platelets, and red. blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma. The PROPPR randomized clinical trial. JAMA. 2015;313(5):471–82.
Recommended Reading
Borgman MA, Spinella PC, Perkins JG, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma. 2007;63(4):805–13.
Young PP, Cotton BA, Goodnough LT. Massive transfusion protocols for patients with substantial hemorrhage. Transfus Med Rev. 2011;25(4):293–303.
Lal DS, Shaz BH. Massive transfusion: blood component ratios. Curr Opin Hematol. 2013;20(6):521–5.
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Friedman, M., West, K., Bizargity, P. (2016). Emergency!. In: Immunohematology and Transfusion Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-22342-1_29
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DOI: https://doi.org/10.1007/978-3-319-22342-1_29
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