Computed Tomography and Magnetic Resonance Imaging

  • Mariana Raditchkova
  • Giorgio TregliaEmail author


The aim of this chapter is to introduce the role of computed tomography (CT) and magnetic resonance imaging (MRI) in patients with endocrine diseases of the neck region.

The role of CT in thyroid disorders is mainly limited to presurgical evaluation to assess the extent of the disease, substernal components, or relationship with extrathyroidal structures. MRI is generally used for specific indications, including the evaluation of substernal goiters and their relation to other structures.

CT and MRI are usually less sensitive than ultrasonography and scintigraphy in detecting hyperfunctioning parathyroid glands. Hybrid tomographic SPECT/CT and four-dimensional CT could be useful alternatives in detecting hyperfunctioning parathyroid glands when previous imaging methods are inconclusive.

In head and neck paragangliomas, accurate diagnosis is usually made by clinical examination together with MRI and hybrid morphological and functional imaging studies, including PET/CT with different tracers.


CT MRI SPECT/CT PET/CT Radiology Endocrine 


  1. 1.
    Vazquez BJ, Richards ML (2011) Imaging of the thyroid and parathyroid glands. Surg Clin North Am 91:15–32CrossRefPubMedGoogle Scholar
  2. 2.
    Weber AL, Randolph G, Aksoy FG (2000) The thyroid and parathyroid glands. CT and MR imaging and correlation with pathology and clinical findings. Radiol Clin North Am 38:1105–1129CrossRefPubMedGoogle Scholar
  3. 3.
    Kirsch E, Hammer B, von Arx G (2009) Graves’ orbitopathy: current imaging procedures. Swiss Med Wkly 139:618–623PubMedGoogle Scholar
  4. 4.
    Hopkins CR, Reading CC (1995) Thyroid and parathyroid imaging. Semin Ultrasound CT MR 16:279–295CrossRefPubMedGoogle Scholar
  5. 5.
    Xue Y-L, Qiu Z-L, Perotti G et al (2013) 131I SPECT/CT: a one-station imaging modality in the management of differentiated thyroid cancer. Clin Transl Imaging 1:163–173CrossRefGoogle Scholar
  6. 6.
    Treglia G, Muoio B, Giovanella L et al (2013) The role of positron emission tomography and positron emission tomography/computed tomography in thyroid tumours: an overview. Eur Arch Otorhinolaryngol 270:1783–1787CrossRefPubMedGoogle Scholar
  7. 7.
    Gotway MB, Higgins CB (2000) MR imaging of the thyroid and parathyroid glands. Magn Reson Imaging Clin N Am 8:163–182PubMedGoogle Scholar
  8. 8.
    Ernst O (2009) Hyperparathyroidism: CT and MR findings. J Radiol 90:409–412CrossRefPubMedGoogle Scholar
  9. 9.
    Rodgers SE, Hunter GJ, Hamberg LM et al (2006) Improved preoperative planning for directed parathyroidectomy with 4-dimensional computed tomography. Surgery 140:932–940CrossRefPubMedGoogle Scholar
  10. 10.
    Treglia G, Sadeghi R, Schalin-Jäntii C et al (2015) Detection rate of (99m) Tc-MIBI SPECT/CT in the preoperative planning of patients with primary hyperparathyroidism: a meta-analysis. Head Neck. doi: 10.1002/hed.24027 PubMedGoogle Scholar
  11. 11.
    Caldarella C, Treglia G, Isgrò MA et al (2013) Diagnostic performance of positron emission tomography using 11C-methionine in patients with suspected parathyroid adenoma: a meta-analysis. Endocrine 43:78–83CrossRefPubMedGoogle Scholar
  12. 12.
    Taïeb D, Kaliski A, Boedeker CC et al (2014) Current approaches and recent developments in the management of head and neck paragangliomas. Endocr Rev 35:795–819PubMedCentralCrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Nuclear Medicine, Thyroid and PET/CT CenterOncology Institute of Southern SwitzerlandBellinzona and LuganoSwitzerland

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