Other Neuroendocrine Tumors of Head and Neck Region

  • Giorgio TregliaEmail author
  • Luca Giovanella


The aim of this chapter is to introduce other neuroendocrine tumors (NETs) of the head and neck region beyond medullary thyroid carcinoma and paragangliomas. NETs of the head and neck are rare neoplasms and can be of epithelial or non-epithelial differentiation. Anatomical and functional imaging can be complementary for the diagnosis, staging, and monitoring of treatment response of these tumors. This chapter briefly describes the imaging methods used to evaluate these tumors and illustrates the imaging features of some NETs of the head and neck region.


Neuroendocrine tumor Neck Small cell carcinoma Carcinoid PET CT MRI 


  1. 1.
    Subedi N, Prestwich R, Chowdhury F et al (2013) Neuroendocrine tumours of the head and neck: anatomical, functional and molecular imaging and contemporary management. Cancer Imaging 13:407–422PubMedCentralCrossRefPubMedGoogle Scholar
  2. 2.
    Castaldi P, Rufini V, Treglia G et al (2008) Impact of 111In-DTPA-octreotide SPECT/CT fusion images in the management of neuroendocrine tumours. Radiol Med 113:1056–1067CrossRefPubMedGoogle Scholar
  3. 3.
    Treglia G, Baldelli R, Cristalli G et al (2013) A rare case of neuroendocrine tumor of the middle ear detected by gallium-68-DOTANOC-PET/CT. J Clin Endocrinol Metab 98:1319–1320CrossRefPubMedGoogle Scholar
  4. 4.
    Treglia G, Bongiovanni M, Paone G et al (2015) Metastatic small cell neuroendocrine carcinoma of the pyriform sinus evaluated by 18F-FDG PET/CT. Rev Esp Med Nucl Imagen Mol 34:125–127PubMedGoogle Scholar
  5. 5.
    Treglia G, Bongiovanni M, Giovanella L (2014) Rare sinonasal small cell neuroendocrine carcinoma evaluated by F-18-FDG PET/MRI. Endocrine 47:654–655CrossRefPubMedGoogle Scholar
  6. 6.
    Treglia G, Salvatori M, Giovanella L (2014) Small cell carcinoma of the thyroid gland with a solid brain metastasis detected by F-18-FDG PET/CT. Endocrine 46:682–683CrossRefPubMedGoogle Scholar
  7. 7.
    Treglia G, Kakhki VR, Giovanella L et al (2013) Diagnostic performance of fluorine-18-fluorodeoxyglucose positron emission tomography in patients with Merkel cell carcinoma: a systematic review and meta-analysis. Am J Clin Dermatol 14:437–447CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Nuclear MedicineThyroid and PET/CT Center, Oncology Institute of Southern SwitzerlandBellinzona and LuganoSwitzerland

Personalised recommendations