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Primary Hyperparathyroidism

  • Jukka Schildt
  • Virpi Tunninen
  • Marko Seppänen
  • Camilla Schalin-JänttiEmail author
Chapter
  • 1.3k Downloads

Abstract

Primary hyperparathyroidism (PHPT) is a common endocrine disorder that especially affects women over 50–60 years [1]. The combination of increased serum calcium and parathyroid hormone (PTH) concentrations confirms the diagnosis. Surgery is the only potentially curative treatment, and there is universal agreement regarding which patients should be referred for surgery and for whom surveillance is sufficient. If the patient is scheduled for surgery, preoperative localization of the abnormal parathyroid gland(s) should be performed in order to help the surgeon plan the surgical strategy. It has been estimated that 60–70 % of patients with PHPT are candidates for unilateral neck exploration. If surgery is not planned, there is no reason to perform preoperative localization studies. Preoperative localization studies are mandatory before reoperation of PHPT. Multiple localization studies are to date available and they can be divided into invasive and noninvasive techniques. Surgery should not be ruled out based on a negative preoperative imaging study. For such cases, bilateral neck exploration is performed as primary surgery.

Keywords

Hyperparathyroidism Imaging Parathyroid Ultrasound, scintigraphy, PET 

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Jukka Schildt
    • 1
  • Virpi Tunninen
    • 2
  • Marko Seppänen
    • 3
  • Camilla Schalin-Jäntti
    • 4
    Email author
  1. 1.Department of Clinical Physiology and Nuclear MedicineUniversity of Helsinki and Helsinki University HospitalHelsinkiFinland
  2. 2.Department of Nuclear MedicineSatakunta Central HospitalPoriFinland
  3. 3.Department of Clinical Physiology and Nuclear MedicineTurku PET Centre, University of Turku and Turku University HospitalTurkuFinland
  4. 4.Division of Endocrinology, Department of MedicineAbdominal Center, University of Helsinki and Helsinki University HospitalHelsinkiFinland

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