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Autoimmune Pancreatitis

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Management of Benign Biliary Stenosis and Injury

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Abstract

Autoimmune pancreatitis (AIP) is a chronic, fibro-inflammatory disease of the pancreas that has been recognized as a distinct clinical entity for approximately two decades. Since patients with this rare disorder commonly present with obstructive jaundice mimicking pancreatic cancer, early recognition and diagnosis of AIP are critical. Over the past few years, AIP has been shown to be comprised of two distinct subtypes—type 1 and type 2 AIP. Type 1 AIP is the pancreatic manifestation of a systemic disorder known as IgG4-related disease, and is commonly associated with extrapancreatic manifestations such as sclerosing cholangitis. On the other hand, type 2 AIP is a pancreatic disorder without extrapancreatic manifestations that is not related to IgG4, and typically occurs in younger patients. This chapter provides a review of current knowledge of autoimmune pancreatitis with a focus on biliary manifestations of the disease.

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Authors and Affiliations

  1. Division of Gastroenterology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Dana 501, Boston, MA, 02215, USA

    Neil Sengupta M.D.

  2. Division of Gastroenterology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Rabb 423, Boston, MA, 02215, USA

    Sunil Sheth M.D.

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  1. Neil Sengupta M.D.
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Correspondence to Sunil Sheth M.D. .

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Editors and Affiliations

  1. Foothills Medical Centre, University of Calgary, Calgary, Alberta, Canada

    Elijah Dixon

  2. Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Charles M. Vollmer Jr.

  3. Division of Gastroenterology, St. Michael's Hospital, Toronto, Ontario, Canada

    Gary R. May

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Sengupta, N., Sheth, S. (2015). Autoimmune Pancreatitis. In: Dixon, E., Vollmer Jr., C., May, G. (eds) Management of Benign Biliary Stenosis and Injury. Springer, Cham. https://doi.org/10.1007/978-3-319-22273-8_6

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  • DOI: https://doi.org/10.1007/978-3-319-22273-8_6

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