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Evolutionary Escape in Populations with Genotype-Phenotype Structure

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Extended Abstracts Spring 2014

Part of the book series: Trends in Mathematics ((RPCRMB,volume 4))

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Abstract

Evolutionary escape is the process whereby a population under sudden changes in the selective pressures acting upon it try to evade extinction by evolving from previously well-adapted phenotypes to those that are favoured by the new selective pressure. This evolutionary process is driven by gene mutations. Some examples are: (1) viruses evading anti-microbial therapy, (2) cancer cells escaping from chemotherapy, (3) parasite infecting a new host, and also (4) species trying to invade a new ecological niche.

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References

  1. T. Alarcón and H.J. Jensen, “Quiescence: a mechanism for escaping the effects of drug on cell populations”. J. R. Soc. Interface 8 (2010), 99–106.

    Google Scholar 

  2. J. Aguirre, J.M. Buldú, M. Stich, and S.C. Manrubia, “Topological sturcture of the space of phenotypes: The case of RNA neutral networks”. PLoS One 6 (2011), e26324.

    Google Scholar 

  3. S. Ciliberti, O.C. Martin, and A. Wagner, “Robustness can evolve gradually in complex regulatory gene networks with varying topology”. PLoS Comput. Biol. 3(2) (2007), e15.

    Google Scholar 

  4. E. Ibáñez-Marcelo and T. Alarcón, “The topology of robustness and evolvability in evolutionary systems with genotype-phenotype map”. J. Theor. Biol. 356 (2014), 144–162.

    Google Scholar 

  5. Y. Iwasa, F. Michor, and M.A. Nowak, “Evolutionary dynamics of invasion and escape”. J. Theor. Biol. 226 (2004), 205–214.

    Google Scholar 

  6. S. Sagitov and M.C. Serra, “Multitype Bienayme–Galton–Watson processes escaping extinction”. Adv. Appl. Prob. 41 (2009), 225–246.

    Google Scholar 

  7. M.C. Serra, “On the waiting time to escape”. J. Appl. Prob. 43 (2006), 296–302.

    Google Scholar 

  8. A. Wagner, “Does evolutionary plasticity evolve?”. Evolution 50 (1996), 1008–1023.

    Google Scholar 

  9. A. Wagner, “Robustness and evolvability in living systems”. Princeton University Press, Princeton, NJ, U.S.A, 2007.

    Google Scholar 

  10. A. Wagner, “Neutralism and selectionism: A network-based reconciliation”. Nature Reviews Genetics 9 (2008), 965–974.

    Google Scholar 

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Correspondence to Tomás Alarcón .

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Ibáñez-Marcelo, E., Alarcón, T. (2015). Evolutionary Escape in Populations with Genotype-Phenotype Structure. In: Corbera, M., Cors, J., Llibre, J., Korobeinikov, A. (eds) Extended Abstracts Spring 2014. Trends in Mathematics(), vol 4. Birkhäuser, Cham. https://doi.org/10.1007/978-3-319-22129-8_19

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