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CPAP Device Therapy for Noninvasive Mechanical Ventilation in Hypoxemic Respiratory Failure: Key Technical Topics and Clinical Implications

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Noninvasive Mechanical Ventilation
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Abstract

Continuous positive airway pressure (CPAP) entails delivering to the opening of the airways, by an external interface or an endotracheal tube, a positive (over-atmospheric) pressure, continuously, during both expiration and inspiration. Although CPAP cannot literally be defined as a noninvasive mechanical ventilation (NIMV) technique, it is often, but not always, noninvasive; it is sometimes mechanically generated, but there are many simpler ways to perform it; and it cannot strictly be considered “ventilation,” because, even if in specific cases CPAP is able to increase alveolar ventilation, it cannot perform any work of breathing (WB).

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Abbreviations

AA:

Acute asthma

ABG:

Arterial blood gas analysis

ACPE:

Acute cardiogenic pulmonary edema

AHRF:

Acute hypoxemic respiratory failure

ARDS:

Acute respiratory distress syndrome

ARF:

Acute respiratory failure

CHF:

Chronic heart failure

COPD:

Chronic obstructive pulmonary disease

CPAP:

Continuous positive airway pressure

DNI:

Do not intubate

ED:

Emergency department

FEV1 :

Forced expiratory volume in 1 second

FiO2 :

Fraction of inspired oxygen

FRC:

Functional residual capacity

HMDU:

High medical dependency unit

ICU:

Intensive care unit

IMV:

Invasive mechanical ventilation

NCPAP:

Noninvasive continuous positive airway pressure

NIMV:

Noninvasive mechanical ventilation

NPPV:

Noninvasive double-level positive pressure ventilation

OOH:

Out of hospital

OSAS:

Obstructive sleep apnea syndrome

PaO2 :

Arterial oxygen pressure

PEEP:

Positive end-expiratory pressure

RCCT:

Randomized controlled clinical trial

RR:

Respiratory rate

SO2T:

Standard oxygen therapy

SpO2 :

Oxygen saturation

TI:

Tracheal intubation

VPM:

Ventilation / perfusion mismatch

WB:

Work of breathing

References

  1. British Thoracic Society Standards of Care Committee. Non invasive ventilation in acute respiratory failure. Thorax. 2002;57:192–211.

    Article  Google Scholar 

  2. Vital FM, Ladeira MT, Atallah AN. Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema. Cochrane Database Syst Rev. 2013;(5):CD005351.

    Google Scholar 

  3. Nava S, Hill N. Non-invasive ventilation in acute respiratory failure. Lancet. 2009;374:250–9.

    Article  PubMed  Google Scholar 

  4. Antonelli M, Conti G, Moro ML, et al. Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multi-centre study. Intensive Care Med. 2001;27:1718–28.

    Article  CAS  PubMed  Google Scholar 

  5. Nava S, Navalesi P, Conti G. Time of non-invasive ventilation. Intensive Care Med. 2006;32:361–70.

    Article  PubMed  Google Scholar 

  6. Mehta S, Hill NS. Noninvasive ventilation. Am J Respir Crit Care Med. 2001;163:540–77.

    Article  CAS  PubMed  Google Scholar 

  7. Carron M, Freo U, BaHammam AS, et al. Complications of non-invasive ventilation techniques: a comprehensive qualitative review of randomized trials. Br J Anaesth. 2013;110:896–914.

    Article  CAS  PubMed  Google Scholar 

  8. Masip J, Roque M, Sànchez B, et al. Noninvasive ventilation in acute cardiogenic pulmonary edema: systematic review and meta-analysis. JAMA. 2005;294:3124–30.

    Article  CAS  PubMed  Google Scholar 

  9. Gray A, Goodacre S, Newby DE, et al. Noninvasive ventilation in acute cardiogenic pulmonary edema. New Engl J Med. 2008;359:142–51.

    Article  CAS  PubMed  Google Scholar 

  10. McDermid RC, Bagshaw SM. Noninvasive ventilation in acute cardiogenic pulmonary edema. New Engl J Med. 2008;359:2068–9.

    Article  CAS  PubMed  Google Scholar 

  11. Masip J, Mebazaa A, Filippatos GS. Noninvasive ventilation in acute cardiogenic pulmonary edema. New Engl J Med. 2008;359:268–9.

    Google Scholar 

  12. Purro A. Questa o quella per me pari sono … due diverse scelte, stessa efficacia: CPAP vs NPPV nell’ACPE. Ital J Emerg Med. 2012;2:15–9 (article in Italian).

    Google Scholar 

  13. Ambrosino N, Vagheggini G. Noninvasive positive pressure ventilation in the acute care setting: where are we? Eur Respir J. 2008;31:874–86.

    Article  CAS  PubMed  Google Scholar 

  14. Ambrosino N, Guarracino F. Unusual applications of noninvasive ventilation. Eur Respir J. 2011;38:440–9.

    Article  CAS  PubMed  Google Scholar 

  15. Hess DR, Pang JM, Camargo JA. A survey of the use of noninvasive ventilation in academic emergency departments in the United States. Respir Care. 2009;54:1306–12.

    PubMed  Google Scholar 

  16. Appendini L, Patessio A, Zanaboni S, et al. Physiologic effects of positive end-expiratory pressure and mask pressure support during exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1994;149:1069–76.

    Article  CAS  PubMed  Google Scholar 

  17. Basner RC. Continuous positive airway pressure for obstructive sleep apnea. New Engl J Med. 2007;356:1751–8.

    Article  CAS  PubMed  Google Scholar 

  18. Squadrone V, Massaia M, Bruno B, et al. Early CPAP prevents evolution of acute lung injury in patients with haematologic malignancy. Intensive Care Med. 2010;36:1666–74.

    Article  PubMed  Google Scholar 

  19. Bello G, De Pascale G, Antonelli M. Noninvasive ventilation for the immunocompromised patient: always appropriate? Curr Opin Crit Care. 2012;18:54–60.

    Article  PubMed  Google Scholar 

  20. Kelly BJ, Matthay MA. Prevalence and severity of neurologic dysfunction in critically ill patients. Influence on need for continued mechanical ventilation. Chest. 1993;104:1818–24.

    Article  CAS  PubMed  Google Scholar 

  21. Cabrini L, Landoni G, Oriani A, et al. Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and meta analysis of randomized controlled trials. Crit Care Med. 2015;43:880–8.

    Article  PubMed  Google Scholar 

  22. Hess DR. Noninvasive ventilation for acute respiratory failure. Respir Care. 2013;58:950–72.

    Article  PubMed  Google Scholar 

  23. Nava S, Ferrer M, Esquinas A, et al. Palliative use of non-invasive ventilation in end-of-life patients with solid tumours: a randomised feasibility trial. Lancet Oncol. 2013;14:219–27.

    Article  PubMed  Google Scholar 

  24. Curtis JR, et al. Noninvasive positive pressure ventilation in critical and palliative care settings: Understanding the goals of therapy. Crit Care Med. 2007;35:932–9.

    Article  PubMed  Google Scholar 

  25. Antro C, Merico F, Urbino R, et al. Non-invasive ventilation as a first-line treatment for acute respiratory failure: “real life” experience in the emergency department. Emerg Med J. 2005;22:772–7.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  26. Bouhemad B, Brisson H, Le-Guen M, et al. Bedside ultrasound assessment of positive end-expiratory pressure–induced lung recruitment. Am J Respir Crit Care Med. 2011;183:341–7.

    Article  PubMed  Google Scholar 

  27. O’Driscoll BR, Howard LS, Davison AG, et al. BTS guideline for emergency oxygen use in adult patients. Thorax. 2008;63 Suppl 6:vi1–68.

    PubMed  Google Scholar 

  28. Parkes SN, Bersten AD. Aerosol kinetics and bronchodilator efficacy during continuous positive airway pressure delivered by face mask. Thorax. 1997;52:171–5.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  29. Dhand R, Tobin M. Inhaled bronchodilator therapy in mechanically ventilated patients. Am J Respir Crit Care Med. 1997;156:3–10.

    Article  CAS  PubMed  Google Scholar 

  30. Hill NS. Where should noninvasive ventilation be delivered? Respir Care. 2009;54:62–70.

    Article  PubMed  Google Scholar 

  31. Elliott MV, Confalonieri M, Nava S. Where to perform noninvasive ventilation? Eur Respir J. 2002;19:1159–66.

    Article  CAS  PubMed  Google Scholar 

  32. Liesching T, Kwok H, Hill NS. Acute application of noninvasive positive pressure ventilation. Chest. 2003;124:699–713.

    Article  PubMed  Google Scholar 

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Correspondence to Rodolfo Ferrari MD .

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Ferrari, R. (2016). CPAP Device Therapy for Noninvasive Mechanical Ventilation in Hypoxemic Respiratory Failure: Key Technical Topics and Clinical Implications. In: Esquinas, A. (eds) Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-319-21653-9_14

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  • DOI: https://doi.org/10.1007/978-3-319-21653-9_14

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21652-2

  • Online ISBN: 978-3-319-21653-9

  • eBook Packages: MedicineMedicine (R0)

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