Abstract
Grief is an internal process that follows experiences of loss and/or psychic injuries and involves an active engagement of the subject. The grieving person recalls his experiences with the loved one and must recognize the loss as permanent and irrevocable. Acute grief and associated symptoms such as pain, sadness, and anger are considered normal processes after bereavement, generally not needing mental health intervention. Research on prolonged grief disorder or complicated grief as well as means to overcome losses like searching for and attributing meaning, narration, and engaging to achieve the aspirations of the deceased person is discussed.
The grieving process in children and adolescents, different from mourning in adults, is addressed. The child has to mourn his loss at different developmental stages and new life events. A child is not able to accomplish a grieving process alone; he needs help from a meaningful adult person, emotionally available in a continuous relationship to fulfill the process of mourning. Psychic manifestations caused by the loss of a parent or a significant caregiver and mourning a sibling are described. The assessment of pathological grief in children must consider the circumstances of the loss, the grieving process, subsequent events, and the personal developmental changes. Traumatic experience of loss in a family, which could not be dealt with and overcome, often represents the starting point for the emergence of family secrets. The consequences of severe psychic traumata can—under certain circumstances—be transmitted from one generation to the next like a cultural heritage.
Attempts are made to clarify the functional neuroanatomical processes involved in the generation of grief. The networks activated during grieving, which produce negative affects, such as the panic–loss system, will ultimately impair the brain reward system leading to further emotional imbalance and depression. The current thinking is to view depression as a multimodal system-level disorder affecting discrete and specific pathways that are altered in response to negative external stimuli. Different approaches to treat depression are briefly presented.
Give sorrow words; the grief that does not speak,
Whispers the o’erfraught heart and bids it break.
(William Shakespeare (1564–1616), Macbeth, Act 4, Scene 3)
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Notes
- 1.
Hamlet, Act I, Scene 5, by William Shakespeare.
- 2.
Winnicott’s concept of holding means safeguarding and maintaining the continuity of the infant’s or child’s experience of being and being alive over time.
- 3.
“One knows that the acute mourning after such a loss will run its course, but one will remain unconsoled and never find a substitute. Everything that takes its place, even if it should fill that place entirely, remains something else. And actually, it’s good that way. It is the only way to continue the love, which after all one does not want to give up” (Freud in a letter to Binswanger, April 11, 1929. 1960: p. 386).
- 4.
Retrospective attribution (Modell 2006) or deferred action (in German Nachträglichkeit) implies a complex and reciprocal relationship between a significant event and its later reinvestment with meaning, a reinvestment that lends it a new psychic efficacy.
- 5.
As part of intersubjective processes, two minds can transmit and receive unconscious “messages.”
- 6.
Panksepp describes seven basic primary emotional subtypes consisting of SEEKING (reward), RAGE, FEAR, sexual LUST, maternal CARE, separation distress PANIC–GRIEF (simply PANIC), and joyful PLAY.
- 7.
Area 25 of Brodmann is located under the anterior part of the corpus callosum and has extensive connections to the nucleus accumbens, the amygdala, the frontal cortex, the thalamus, and the periacqueductal gray. Dysfunction of this area can therefore result in an imbalance of many functional circuits.
- 8.
The many different targets that are stimulated in depression reflect the conflicting views on the pathogenesis of this condition. For example, if depression is viewed as a consequence of anhedonia, the medial forebrain bundle, part of the reward system, is stimulated. Not all patients undergoing DBS will improve and there is a lack of controlled studies, so that the method remains experimental. How DBS “resets” a circuit or corrects a chemical imbalance remains to be shown (Underwood 2013).
References
Abraham N, Torok M. L’ecorce et le noyau. Paris: Flammarion; 1987.
Bürgin D, Steck B. Indikation psychoanalytischer Psychotherapie bei Kindern und Jugendlichen, Diagnostisch-therapeutisches Vorgehen und Fallbeispiele. Stuttgart: Klett-Cotta; 2013. ISBN 978-3-608-94829-5.
Coenen VA, Honey CR, Hurwitz T, Rahman AA, McMaster J, Bürgel U, et al. Medial forebrain bundle stimulation as a pathophysiological mechanism for hypomania in subthalamic nucleus deep brain stimulation for Parkinson’s disease. Neurosurgery. 2009;64(6):1106–14. doi:10.1227/01.NEU.0000345631.54446.06; discussion 1114-5.
Coenen VA, Panksepp J, Hurwitz TA, Urbach H, Mädler B. Human medial forebrain bundle (MFB) and anterior thalamic radiation (ATR): imaging of two major subcortical pathways and the dynamic balance of opposite affects in understanding depression. J Neuropsychiatry Clin Neurosci. 2012 Spring;24(2):223–36. doi:10.1176/appi.neuropsych.11080180.
Christian C. Sibling loss, guilt and reparation: a case study. Int J Psychoanal. 2007;88:41–54.
Damasio AR, Grabowski TJ, Bechara A, Damasio H, Ponto LL, Parvizi J, et al. Subcortical and cortical brain activity during the feeling of self-generated emotions. Nat Neurosci. 2000;3(10):1049–56.
Diatkine G. Chasseurs de fantômes, dans: le secret sur les origines; problèmes psychologiques, légaux, administratifs. Paris: Editions ESF; 1986. p. 71–90.
De Saint-Exupéry A. Le Petit Prince. Paris: Gallimard; 1945.
Eisenberger NI, Lieberman MD, Williams KD. Does rejection hurt? An FMRI study of social exclusion. Science. 2003;302(5643):290–2.
Faimberg H. The telescoping of generations. London: Routledge; 2005.
Freud S. Mourning and melancholia, Standard edition, vol. XVII. London: Hogarth Press; 1917. p. 237–60.
Freud S. An autobiographical study, inhibitions, symptoms and anxiety, the question of lay analysis and other works, Standard edition, vol. XX. London: Hogarth Press; 1925–1926.
Freud S. The future of an illusion, civilization and its discontents, and other works, Standard edition, vol. XXI. London: Hogarth Press; 1927–1931.
Freud S. Letter to Binswanger. Letter 239, 1929. In: Freud EL, editor. The letters of Sigmund Freud. New York: Basic Books; 1960.
Gibbons RD, Hur K, Brown CH, Davis JM, Mann JJ. Benefits from antidepressants: synthesis of 6-week patient-level outcomes from double-blind placebo-controlled randomized trials of fluoxetine and venlafaxine. Arch Gen Psychiatry. 2012;69(6):572–9. doi:10.1001/archgenpsychiatry.2011.2044.
Ikemoto S, Panksepp J. The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res Brain Res Rev. 1999;31(1):6–41. Review.
Kernberg O. Some observations on the process of mourning. Int J Psychoanal. 2010;91:601–19.
Kestenberg J. What a psychoanalyst learned from the holocaust and genocide. Int J Psychoanal. 1993;74:1117–29.
Khan M. The privacy of the self. London: Hogarth; 1976.
Kogan I. The cry of mute children. London: Free Association Books; 1995.
Kubler-Ross E. On death and dying. New York: Macmillan; 1969.
Laplanche J. Essays on otherness. London: Routledge; 1999.
Lesch KP, Araragi N, Waider J, van den Hove D, Gutknecht L. Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour. Philos Trans R Soc Lond B Biol Sci. 2012;367(1601):2426–43. doi:10.1098/rstb.2012.0039. Review.
Li K, Zhou T, Liao L, Yang Z, Wong C, Henn F, et al. βCaMKII in lateral habenula mediates core symptoms of depression. Science. 2013;341(6149):1016–20. doi:10.1126/science.1240729.
Lichtenthal WG, Currier JM, Neimeyer RA, Keesee NJ. Sense and significance: a mixed methods examination of meaning making after the loss of one’s child. J Clin Psychol. 2010;66(7):791–812. doi:10.1002/jclp.20700.
Manzano J. La séparation et la perte d’objet chez l’enfant. Un point de vue sur le processus analytique. Rev Franç Psychanal. 1989;1:241–72.
Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C, et al. Deep brain stimulation for treatment-resistant depression. Neuron. 2005;45(5):651–60.
Mayberg HS. Neuroimaging and psychiatry: the long road from bench to bedside. Hastings Cent Rep. 2014;Spec No:S31-6. doi:10.1002/hast.296.
Melhem NM, Moritz MPH, Walker MSW, Shear MK, Brent D. Phenomenology and correlates of complicated grief in children and adolescents. J Am Acad Child Adolesc Psychiatry. 2007;46:493–9.
Melhem NM, Walker M, Moritz G, Brent DA. Antecedents and sequelae of sudden parental death in offspring and surviving caregivers. Arch Pediatr Adolesc Med. 2008;162(5):403–10.
Melhem NM, Porta G, Walker Payne M, Brent DA. Identifying prolonged grief reactions in children: dimensional and diagnostic approaches. J Am Acad Child Adolesc Psychiatry. 2013;52(6):599–607.e7. doi:10.1016/j.jaac.2013.02.015.
Messina I, Sambin M, Palmieri A, Viviani R. Neural correlates of psychotherapy in anxiety and depression: a meta-analysis. PLoS One. 2013;8(9), e74657. doi:10.1371/journal.pone.0074657.%20eCollection%202013.
Modell AH. Imagination and the meaningful brain. Cambridge: MIT Press; 2006.
Nachin C. Les fantômes de l’âme. Paris: L’Harmattan; 1993.
Neimeyer RA, Baldwin SA, Gillies J. Continuing bonds and reconstructing meaning: mitigating complications in bereavement. Death Stud. 2006;30(8):715–38.
Neimeyer RA. Reconstructing meaning in bereavement. Riv Psichiatr. 2011;46(5-6):332–6.
Nemeroff CB, Heim CM, Thase ME, Klein DN, Rush AJ, Schatzberg AF, et al. Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma. Proc Natl Acad Sci U S A. 2003;100(24):14293–6.
Nietzsche F. The will to power. In: Kaufman W, editor. (Kaufman W, Hollingdale RJ, trans.). New York: Vintage Books; 1967.
Oliner M. Hysterische Persönlichkeitsmerkmale bei Kindern Überlebender. In: Bergmann M, Jucovy M, Kestenberg J, Hrsg. Kinder der Opfer Kinder der Täter S. . Fischer Verlag GmbH: Frankfurt am Main; 1995.
Owens MJ, Nemeroff CB. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clin Chem. 1994;40(2):288–95.
Panksepp J. Cross-species affective neuroscience decoding of the primal affective experiences of humans and related animals. PLoS One. 2011;6(9), e21236. doi:10.1371/journal.pone.0021236. Review.
Shakespeare W. Macbeth, Act 4, Scene 3 (1564–1616)
Shear MK, Simon N, Wall M, Zisook S, Neimeyer R, Duan N, et al. Complicated grief and related bereavement issues for DSM-5. Depress Anxiety. 2011;28(2):103–17, p. 105.
Shear MK. Grief and mourning gone awry: pathway and course of complicated grief. Dialogues Clin Neurosci. 2012;14:119–28.
Simon NM. Treating complicated grief. JAMA. 2013;310(4):416–23.
Spuij M, Reitz E, Prinzie P, Stikkelbroek Y, de Roos C, Boelen PA. Distinctiveness of symptoms of prolonged grief, depression, and post-traumatic stress in bereaved children and adolescents. Eur Child Adolesc Psychiatry. 2012;21(12):673–9. doi:10.1007/s00787-012-0307-4.
Stroebe WT, Schut H, Stroebe MS. Grief work, disclosure and counseling: do they help the bereaved? Clin Psychol Rev. 2005;25:395–414.
Stroebe M, Schut H, Stroebe W. Health outcomes of bereavement. Lancet. 2007;370:1960–73.
Steck B, Bürgin D. Über die Unmöglichkeit zu trauern bei Kindern trauerkranker Eltern. Kinderanalyse. 1996;4:351–61.
Taiana C. Mourning the dead, mourning the disappeared: the enigma of the absent–presence. Int J Psychoanal. 2014;95:1087–107. doi:10.1111/1745-8315.12237.
Tisseron S. Tintin et les secrets de famille. Paris: Aubier; 1992.
Underwood E. Short-circuiting depression. Science. 2013;342(6158):548–51. doi:10.1126/science.342.6158.548.
Vanderwerker LC, Jacobs SC, Parkes CM, Prigerson HG. An exploration of associations between separation anxiety in childhood and complicated grief in later life. J Nerv Ment Dis. 2006;194(2):121–3.
Winnicott DW. The maturational processes and the facilitating environment: studies in the theory of emotional development. London: Hogarth; 1965.
Zellner MR, Watt DF, Solms M, Panksepp J. Affective neuroscientific and neuropsychoanalytic approaches to two intractable psychiatric problems: why depression feels so bad and what addicts really want. Neurosci Biobehav Rev. 2011;35(9):2000–8. doi:10.1016/j.neubiorev.2011.01.003.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Steck, A., Steck, B. (2016). Grief. In: Brain and Mind. Springer, Cham. https://doi.org/10.1007/978-3-319-21287-6_14
Download citation
DOI: https://doi.org/10.1007/978-3-319-21287-6_14
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-21286-9
Online ISBN: 978-3-319-21287-6
eBook Packages: MedicineMedicine (R0)