Abstract
Historically anticoagulation involved the use of heparin and its derivatives or warfarin. However, the past few years have seen the introduction of a number of novel direct oral anticoagulants. These drugs are of interest as they require no laboratory monitoring, are relatively easy to use as they have a fixed dose and have demonstrated equivalence and in some cases superiority to warfarin, in the prevention of cardioembolic stroke in individuals with non-valvular atrial fibrillation, in deep vein thrombosis (DVT) prevention in patients undergoing hip and knee replacement surgery and in the treatment of DVT and pulmonary embolism (PE).
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Perry, D. (2016). Overview of anticoagulants. In: Perry, D., Warwick, D. (eds) Handbook of Thromboprophylaxis. Adis, Cham. https://doi.org/10.1007/978-3-319-21148-0_2
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DOI: https://doi.org/10.1007/978-3-319-21148-0_2
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