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Let’s Talk About… Synthetic Biology—Emerging Technologies and the Public

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Ambivalences of Creating Life

Part of the book series: Ethics of Science and Technology Assessment ((ETHICSSCI,volume 45))

Abstract

Synthetic biology has emerged in the past decade when advanced biotechnological methods have increased the ability to design and build robust and predictable biological systems using engineering design principles. Synthetic biology is expected to contribute to solving the world’s most significant challenges including energy supply, disease control, or even the remediation of polluted sites. Nevertheless, possible societal implications and risk analyses have been topics of scientific debate since its very beginning and synthetic biology has become a subject for Technology Assessment. Following the tradition of social constructivist studies of science and technology, the notions of public participation and engagement become prominent in order to answer the question of how to govern emerging technologies like synthetic biology. This is reinforced in the context of the concept of responsible research and innovation, which explicitly asks for more public participation aiming on avoidance of conflicts and enabling successful innovations that are adapted to societal values and needs. However, still little is known about synthetic biology in the public which is demonstrated for the chase of Germany. Moreover, this chapter considers why and how public engagement can contribute to the assessment and governance of synthetic biology and what should be considered when using the according methods.

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Notes

  1. 1.

    In the literature “boundary objects” (Star and Griesemer 1989; Guston 2001) or “umbrella terms” (Rip and Voß 2013) describe terms that are not precisely defined. Therefore, they are vague enough to be used by quite diverse groups or disciplines and allow for interpretations. At the same time they are sufficiently defined to keep some kind of global identity and guarantee a shared understanding.

  2. 2.

    More information can be found at http://biobricks.org. Accessed 14 Aug 2014.

  3. 3.

    Systems biology is an interdisciplinary field that combines quantitative data generation and mathematical modelling with biomedical laboratory experiments to elucidate general principles governing the properties of complex systems that give rise to biological functions.

  4. 4.

    This becomes even more evident in the interpretation of synthetic biology for military use as illustrated in the Official US Department of Defence Science Blog “Armed with Science”, where a programme manager of the Defence Advanced Research Projects Agency, Justin Gallivan, states: “By making these systems more robust, stable and safe, BRICS seeks to harness the full range of capabilities at the intersection of engineering and biology”. http://science.dodlive.mil/2014/08/12/the-future-of-synthetic-biology-applications. Accessed 14 Aug 2014.

  5. 5.

    More information can be found at http://cordis.europa.eu/fp6/nest.htm. Accessed 14 Aug 2014.

  6. 6.

    In the case of synthetic biology, it is essential to consider the precautionary principle: Once “synthetic organisms” as products of the “synthetic biology technology” have been released, they cannot be retrieved or even traced.

  7. 7.

    EU27 includes the member states of the European Union as of June 2013.

  8. 8.

    More information available at: http://www.synbioproject.org/process/assets/files/6655/synbiosurvey2013.pdf. Accessed 14 Aug 2014.

  9. 9.

    Steurer (in this volume) presents the results of this kind of method—citizens panels and focus groups—for analyses on public debate/perceptions in Austria.

  10. 10.

    For more information see: http://www.synenergene.eu/. Accessed 14 Aug 2014.

  11. 11.

    That applies only if on assumes that media consumers take up the presented topic as well as the framing used by the journalists (Brüggemann 2014). Here, it is worth mentioning that the assessment of media effects on the recipient side regarding the consequences for opinion-forming or decision-making is accordingly demanding and maybe even impossible (Bonfadelli and Friemel 2011).

  12. 12.

    Although the print media is still the number one information resource, there is a shift towards a more mixed usage of resources including TV and the Internet (Eurobarometer 2013). Access to the latter is much more time-consuming and cost-intensive and their analysis much more elaborate; scientific approaches are still in a rather experimental state (Mitchelstein and Boczkowski 2010).

  13. 13.

    The international Genetically Engineered Machine (iGEM) competition is a worldwide synthetic biology competition for young talents (university and high school students) that aims at raising attention for the field. More information at www.igem.org. Accessed 14 Aug 2014.

  14. 14.

    A quantitative and qualitative analysis for the period between August 31, 2011 and December 31, 2014 was done in the framework of the EA Summer School as described in Lehmkuhl (2011, p. 20): Using the GENIOS database and the German search term “synthetische Biologie”.

  15. 15.

    The Gartner Hype Cycle represents a “graphic representation of the maturity and adoption of technologies and applications, and how they are potentially relevant to solving real business problems and exploiting new opportunities”. More information can be found at http://www.gartner.com/technology/research/methodologies/hype-cycle.jsp and http://www.spiegel.de/netzwelt/tech/aufmerksamkeits-kurven-die-hype-zyklen-neuer-technologien-a-443717.html. Accessed 14 Aug 2014.

  16. 16.

    Ancillotti and Eriksson (this volume) show for Swedish and Italian press, which also covered synthetic biology more extensively in 2010, that this event was indeed the main topic in that year.

  17. 17.

    For limitations of this approach see footnote 11.

  18. 18.

    Still there are no indications that this is the case: David Shukman “Will synthetic biology become a GM-style battleground?” BBC News, July 21, 2014. http://www.bbc.com/news/science-environment-23274175. Accessed 14 Aug 2014.

  19. 19.

    “Linear” referrers here to classic innovation theories which locates the creative potential solely at the side of the researches and developers. The public as potential users is reflected by the market that either accepts or rejects the invention. In more recent theories address the interconnectivity of today’s innovation processes.

  20. 20.

    More information can be found at: http://ec.europa.eu/programmes/horizon2020/ and http://ec.europa.eu/programmes/horizon2020/en/h2020-section/responsible-research-innovation. Accessed 14 Aug 2014.

  21. 21.

    For a persuasive example see Molyneux-Hodgson and Balmer (2014) who analyse the performance of a synthetic biology research programme that sought to address issues of innovation in the water industry. They found that the conceptualisation of public actors as consumers who are ignorant of the complexities of water and its true value became an innovation barrier.

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Seitz, S.B. (2016). Let’s Talk About… Synthetic Biology—Emerging Technologies and the Public. In: Hagen, K., Engelhard, M., Toepfer, G. (eds) Ambivalences of Creating Life. Ethics of Science and Technology Assessment, vol 45. Springer, Cham. https://doi.org/10.1007/978-3-319-21088-9_8

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