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Is It Ethical to Condone Low Levels of Drinking in Pregnancy?

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Part of the book series: International Library of Ethics, Law, and the New Medicine ((LIME,volume 63))

Abstract

Today, it is widely agreed that exposure to very large doses of alcohol during pregnancy acts as a teratogen that can cause structural damage to specific parts of the brain including the corpus callosum, cerebellum and hippocampal areas.

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References

  • Abel, E.L. 1998a. Neurodevelopmental abnormalities. Structural and sensory. Fetal alcohol abuse syndrome, 101–110. New York: Plenum

    Google Scholar 

  • Abel, E.L. 1998b. Neurodevelopmental abnormalities. Behavioural and cognitive. Fetal alcohol abuse syndrome, 111–138. New York: Plenum.

    Google Scholar 

  • Ainsworth, M.D., and S.M. Bell. 1970. Attachment, exploration, and separation: Illustrated by the behavior of one-year-olds in a strange situation. Child Development 41(1): 49–67.

    Article  Google Scholar 

  • Astley, S.J. 2010. Profile of the first 1,400 patients receiving diagnostic evaluations for fetal alcohol spectrum disorder at the Washington State Fetal Alcohol Syndrome Diagnostic & Prevention Network. The Canadian Journal of Clinical Pharmacology 17(1): e132–e164.

    Google Scholar 

  • Astley, S., and T. Grant. 2012. Another perspective on ‘the effect of different alcohol drinking patterns in early to mid pregnancy on the child’s intelligence, attention, and executive function’. BJOG 119(13): 1672–1675.

    Article  Google Scholar 

  • Bowlby, J. 1950. Research into the Origins of Delinquent Behaviour. British Medical Journal 1(4653): 570–573.

    Article  Google Scholar 

  • Braun, J.M., R.S. Kahn, T. Froehlich, P. Auinger, and B.P. Lanphear. 2006. Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. children. Environmental Health Perspectives 114(12): 1904–1909.

    Google Scholar 

  • Burke, M.W., R.M. Palmour, F.R. Ervin, and M. Ptito. 2009. Neuronal reduction in frontal cortex of primates after prenatal alcohol exposure. NeuroReport 20(1): 13–17.

    Article  Google Scholar 

  • Calhoun, F., and K. Warren. 2007. Fetal alcohol syndrome: Historical perspectives. Neuroscience and Biobehavioral Reviews 31(2): 168–171.

    Article  Google Scholar 

  • Chen, W.J., S.E. Maier, S.E. Parnell, and J.R. West. 2003. Alcohol and the developing brain: neuroanatomical studies. Alcohol Research and Health 27(2): 174–180.

    Google Scholar 

  • D’Onofrio, B.M., C.A. Van Hulle, I.D. Waldman, J.L. Rodgers, P.J. Rathouz, and B.B. Lahey. 2007. Causal inferences regarding prenatal alcohol exposure and childhood externalizing problems. Archives of General Psychiatry 64(11): 1296–1304.

    Article  Google Scholar 

  • Driscoll, C.D., A.P. Streissguth, and E.P. Riley. 1990. Prenatal alcohol exposure: comparability of effects in humans and animal models. Neurotoxicology and Teratology 12(3): 231–237.

    Article  Google Scholar 

  • Eriksen, H.L.F., E.L. Mortensen, T. Kilburn, et al. 2012. The effects of low to moderate prenatal alcohol exposure in early pregnancy on IQ in 5-year-old children. BJOG 119(10): 1191–1200.

    Article  Google Scholar 

  • Flak, A.L., S. Su, J. Bertrand, C.H. Denny, U.S. Kesmodel, and M.E. Cogswell. 2013. The association of mild, moderate, and binge prenatal alcohol exposure and child neuropsychological outcomes: A meta-analysis. Alcoholism: Clinical and Experimental Research.

    Google Scholar 

  • Fried, P.A., and B. Watkinson. 1988. 12- and 24-month neurobehavioural follow-up of children prenatally exposed to marihuana, cigarettes and alcohol. Neurotoxicology and Teratology 10(4): 305–313.

    Article  Google Scholar 

  • George, M.D. 1951. London life in the eighteen century.

    Google Scholar 

  • Gray, R., R.A. Mukherjee, and M. Rutter. 2009. Alcohol consumption during pregnancy and its effects on neurodevelopment: What is known and what remains uncertain. Addiction 104(8): 1270–1273.

    Article  Google Scholar 

  • Garcia-Algar, O., D. Black, C. Guerri, and S. Pichini. 2012. The effect of different alcohol drinking patterns in early to mid-pregnancy. BJOG 119(13): 1670–1671.

    Article  Google Scholar 

  • Gray, R., and J. Henderson. 2007b. Review of the fetal effects of prenatal alcohol exposure. Oxford: National Perinatal Epidemiology Unit, University of Oxford.

    Google Scholar 

  • Gray, R., and J. Henderson. 2007a. Rewiev of the fetal effects of prenatal alcohol exposure. Oxford: National Perinatal Epidemiology Unit, University of Oxford.

    Google Scholar 

  • Guerri, C., A. Bazinet, and E.P. Riley. 2009. Foetal alcohol spectrum disorders and alterations in brain and behaviour. Alcohol and Alcoholism 44(2): 108–114.

    Article  Google Scholar 

  • Henderson, J., R. Gray, and P. Brocklehurst. 2007a. Systematic review of effects of low-moderate prenatal alcohol exposure on pregnancy outcome. BJOG 114(3): 243–252.

    Article  Google Scholar 

  • Henderson, J., R. Gray, P. Brocklehurst. 2007b. Systematic review of effects of low–moderate prenatal alcohol exposure on pregnancy outcome.

    Google Scholar 

  • Henderson, J., U. Kesmodel, and R. Gray. 2007c. Systematic review of the fetal effects of prenatal binge drinking. Journal of Epidemiology and Community Health 61: 1069–1073.

    Article  Google Scholar 

  • Ikonomidou, C., P. Bittigau, M.J. Ishimaru, et al. 2000. Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science 287(5455): 1056–1060.

    Article  Google Scholar 

  • Jones, K.L. 2012. FASD from a historical perspective. Barcelona, Spain.

    Google Scholar 

  • Jones, K.L., and D.W. Smith. 1973. Recognition of the fetal alcohol syndrome in early infancy. Lancet 302(7836): 999–1001.

    Article  Google Scholar 

  • Jones, K.L., D.W. Smith, C.N. Ulleland, and P. Streissguth. 1973. Pattern of malformation in offspring of chronic alcoholic mothers. Lancet 1(7815): 1267–1271.

    Article  Google Scholar 

  • Jones, K.L., D.W. Smith, A.P. Streissguth, and N.C. Myrianthopoulos. 1974. Outcome in offspring of chronic alcoholic women. Lancet 1(7866): 1076–1078.

    Article  Google Scholar 

  • Juul, S. 2008. Epidemiologi og evidens, 1st edn. Munksgaard.

    Google Scholar 

  • Kelly, Y., A. Sacker, R. Gray, J. Kelly, D. Wolke, and M.A. Quigley. 2009. Light drinking in pregnancy, a risk for behavioural problems and cognitive deficits at 3 years of age? International Journal of Epidemiology 38(1): 129–140.

    Article  Google Scholar 

  • Kelly, Y.J., A. Sacker, R. Gray, et al. 2010. Light drinking during pregnancy: Still no increased risk for socioemotional difficulties or cognitive deficits at 5 years of age? Journal of epidemiology and community health.

    Google Scholar 

  • Kesmodel, U. 2001. Binge drinking in pregnancy–frequency and methodology. American Journal of Epidemiology 154(8): 777–782.

    Article  Google Scholar 

  • Kesmodel, U., and M. Frydenberg. 2004. Binge drinking during pregnancy—is it possible to obtain valid information on a weekly basis? American Journal of Epidemiology 159(8): 803–808.

    Article  Google Scholar 

  • Kesmodel, U.S., H.L. Eriksen, M. Underbjerg, et al. 2012. The effect of alcohol binge drinking in early pregnancy on general intelligence in children. BJOG 119(10): 1222–1231.

    Article  Google Scholar 

  • Kodituwakku, P.W., W. Kalberg, and P.A. May. 2001a. The effects of prenatal alcohol exposure on executive functioning. Alcohol Research and Health 25(3): 192–198.

    Google Scholar 

  • Kodituwakku, P.W., P.A. May, C.L. Clericuzio, and D. Weers. 2001b. Emotion-related learning in individuals prenatally exposed to alcohol: an investigation of the relation between set shifting, extinction of responses, and behavior. Neuropsychologia 39(7): 699–708.

    Article  Google Scholar 

  • Larroque, B., and M. Kaminski. 1998. Prenatal alcohol exposure and development at preschool age: Main results of a French study. Alcoholism, Clinical and Experimental Research 22(2): 295–303.

    Article  Google Scholar 

  • Latimer, K., P. Wilson, J. Kemp, et al. 2012. Disruptive behaviour disorders: a systematic review of environmental antenatal and early years risk factors. Child: Care, Health and Development 38(5): 611–628.

    Google Scholar 

  • Linnet, K.M., K. Wisborg, NJ Secher, et al. 2009. Coffee consumption during pregnancy and the risk of hyperkinetic disorder and ADHD: A prospective cohort study. Acta Paediatrica 98(1): 173–179.

    Google Scholar 

  • Linnet, K.M., S. Dalsgaard, C. Obel, et al. 2003. Maternal lifestyle factors in pregnancy risk of attention deficit hyperactivity disorder and associated behaviors: review of the current evidence. American Journal of Psychiatry 160(6): 1028–1040.

    Article  Google Scholar 

  • MacNicholl, T.A. 1905. A study of the effects of alcohol on school children. Quarterly Journal of Inebriety 27: 113–117.

    Google Scholar 

  • Mattson, S.N., and E.P. Riley. 1998. A review of the neurobehavioral deficits in children with fetal alcohol syndrome or prenatal exposure to alcohol. Alcoholism, Clinical and Experimental Research 22(2): 279–294.

    Article  Google Scholar 

  • Mick, E., J. Biederman, and S.V. Faraone. 1996. Is season of birth a risk factor for attention-deficit hyperactivity disorder? Journal of the American Academy of Child and Adolescent Psychiatry 35(11): 1470–1476.

    Article  Google Scholar 

  • Mikulincer M., P.R. Shaver. 2007a. Attachment in adulthood. Structure, dynamics and change, 1st edn. New York: The Guildford Press.

    Google Scholar 

  • Mikulincer M., P.R. Shaver. 2007b. Attachment orientations, behavioural self-regulation, and personal growth. Attachment in adulthood. Structure, dynamics and change, 1st edn., 219–250. New York: The Guildford Press.

    Google Scholar 

  • NIAAA: National Institute of Alcohol Abuse and Alcoholism. 2000. 10th special report to the US congress on alcohol and health. Highlights from current research. Bethesda: Department of health and human services; Report No.: 00-1583.

    Google Scholar 

  • Niclasen, J. 2012. SDQ Danish cut off scores: 5–7-year-olds. 18-12-2012.

    Google Scholar 

  • Niclasen, J. 2014. Drinking or not drinking in pregnancy: The multiplicity of confounding influences. Alcohol and Alcoholism 49(3): 349–355.

    Article  Google Scholar 

  • Niclasen, J., A.M. Andersen, T.W. Teasdale, and K. Strandberg-Larsen. 2013. Binge drinking and cumulated alcohol exposure in pregnancy: behavioural and emotional development at age seven. Journal Epidemiology and Community Health.

    Google Scholar 

  • Niclasen J, T.W. Teasdale, K. Strandberg-Larsen, and A.M. Nybo Andersen. 2013. Is alcohol binge drinking in early and late pregnancy associated with Behavioural and Emotional Development at Age Seven? European Journal of Child and Adolescent Psychiatry.

    Google Scholar 

  • O’Leary, C.M. 2004. Fetal alcohol syndrome: Diagnosis, epidemiology, and developmental outcomes. Journal of Paediatrics and Child Health 40(1–2): 2–7.

    Article  Google Scholar 

  • Obel, C., E. Heiervang, A. Rodriguez, et al. 2004. The strengths and difficulties questionnaire in the Nordic countries. European Child and Adolescent Psychiatry 13(Suppl 2): II32-9:II32-II39.

    Google Scholar 

  • Obel, C., K.M. Linnet, TB Henriksen, et al. 2008. Smoking during pregnancy and hyperactivity-inattention in the offspring—comparing results from three Nordic cohorts. The International Journal of Epidemiology.

    Google Scholar 

  • O’Leary, C.M., S.R. Zubrick, C.L. Taylor, G. Dixon, and C. Bower. 2009. Prenatal alcohol exposure and language delay in 2-year-old children: the importance of dose and timing on risk. Pediatrics 123(2): 547–554.

    Article  Google Scholar 

  • O’Leary, C.M., C. Bower, S.R. Zubrick, E. Geelhoed, J.J. Kurinczuk, and N. Nassar. 2010. A new method of prenatal alcohol classification accounting for dose, pattern and timing of exposure: Improving our ability to examine fetal effects from low to moderate alcohol. Journal of Epidemiology and Community Health 64(11): 956–962.

    Article  Google Scholar 

  • Olson, H.C., A.P. Streissguth, P.D. Sampson, H.M. Barr, F.L. Bookstein, and K. Thiede. 1997. Association of prenatal alcohol exposure with behavioral and learning problems in early adolescence. Journal of the American Academy of Child and Adolescent Psychiatry 36(9): 1187–1194.

    Article  Google Scholar 

  • Parker, M.O., and C.H. Brennan. 2012. Low and moderate alcohol consumption during pregnancy: Effects on social behaviour and propensity to develop substance abuse in later life. BJOG 119(13): 1671–1672.

    Article  Google Scholar 

  • Plant, M.L., E.L. Abel, and C. Guerri. 1999. Alcohol and pregnancy. In Health issues related to alcohol consumption, ed. I. MacDonald, 2nd edn. ILSI Europe; 1999. 181–214.

    Google Scholar 

  • Porta, M. 2008. A dictionary of epidemiology. Oxford: Oxford University Press.

    Google Scholar 

  • Powell, G. 2012. Danish studies suggesting low and moderate prenatal alcohol exposure has no adverse effects on children aged 5 years did not use appropriate or effective measures of executive functioning. BJOG 119(13): 1669–1670.

    Article  Google Scholar 

  • Randall, C.L. 2001. Alcohol and pregnancy: Highlights from three decades of research. Journal of Studies on Alcohol 62(5): 554–561.

    Article  Google Scholar 

  • Rasmussen, C., G. Andrew, L. Zwaigenbaum, and S. Tough. 2008. Neurobehavioural outcomes of children with fetal alcohol spectrum disorders: A Canadian perspective. Paediatrics and Child Health 13(3): 185–191.

    Google Scholar 

  • Riley, E.P., E.A. Lochry, and N.R. Shapiro. 1979. Lack of response inhibition in rats prenatally exposed to alcohol. Psychopharmacology (Berl) 62(1): 47–52.

    Article  Google Scholar 

  • Robinson, M., W.H. Oddy, N.J. McLean, et al. 2010. Low-moderate prenatal alcohol exposure and risk to child behavioural development: A prospective cohort study. BJOG 117(9): 1139–1150.

    Article  Google Scholar 

  • Rodriguez, A., J. Miettunen, T.B. Henriksen, et al. 2008. Maternal adiposity prior to pregnancy is associated with ADHD symptoms in offspring: Evidence from three prospective pregnancy cohorts. The International Journal of Obesity (London) 32(3): 550–557.

    Article  Google Scholar 

  • Rodriguez, A., J. Olsen, A.J. Kotimaa, et al. 2009. Is prenatal alcohol exposure related to inattention and hyperactivity symptoms in children? Disentangling the effects of social adversity. Journal of Child Psychology and Psychiatry 50(9): 1073–1083.

    Article  Google Scholar 

  • Rothman, K.J. 2002. Epidemiology. An intoduction. Oxford: Oxford University Press.

    Google Scholar 

  • Rutter, M., A. Pickles, R. Murray, and L. Eaves. 2001. Testing hypotheses on specific environmental causal effects on behavior. Psychological Bulletin 127(3): 291–324.

    Article  Google Scholar 

  • Sayal, K. 2007. Alcohol consumption in pregnancy as a risk factor for later mental health problems. Evidence-Based Mental Health 10(4): 98–100.

    Article  Google Scholar 

  • Sayal, K., J. Heron, J. Golding, and A. Emond. 2007. Prenatal alcohol exposure and gender differences in childhood mental health problems: A longitudinal population-based study. Pediatrics 119(2): e426–e434.

    Article  Google Scholar 

  • Sayal, K., J. Heron, J. Golding, et al. 2009. Binge pattern of alcohol consumption during pregnancy and childhood mental health outcomes: Longitudinal population-based study. Pediatrics 123(2): e289–e296.

    Article  Google Scholar 

  • Sayal, K., E.S. Draper, R. Fraser, M. Barrow, S.G. Davey, and R. Gray. 2013. Light drinking in pregnancy and mid-childhood mental health and learning outcomes. Archives of Disease in Childhood 98(2): 107–111.

    Google Scholar 

  • Schneider, M.L., C.F. Moore, and E.F. Becker. 2001. Timing of moderate alcohol exposure during pregnancy and neonatal outcome in rhesus monkeys (Macaca mulatta). Alcoholism, Clinical and Experimental Research 25(8): 1238–1245.

    Article  Google Scholar 

  • Skogerbo, A., U.S. Kesmodel, T. Wimberley, et al. 2012. The effects of low to moderate alcohol consumption and binge drinking in early pregnancy on executive function in 5-year-old children. BJOG 119(10): 1201–1210.

    Article  Google Scholar 

  • Sood, B., V. Aney-Black, C. Covington, et al. 2001. Prenatal alcohol exposure and childhood behavior at age 6 to 7 years: I. Dose-response effect. Pediatrics 108(2): E34.

    Google Scholar 

  • Sroufe, L.A. 2005. Attachment and development: a prospective, longitudinal study from birth to adulthood. Attachment & Human Development 7(4): 349–367.

    Article  Google Scholar 

  • Stratton, K., C. Howe, F. Battaglia. 1996. Fetal alcohol syndrome. Diagnosis, epidemiology, prevention and treatment. Washington, D. C.: National Academy Press.

    Google Scholar 

  • Streissguth, A.P., H.M. Barr, J. Kogan, F.L. Bookstein. 1996. Understanding the occurence of secondary disabilities in clients with fetal alcohol syndrome (FAS) and fetal alcohol effcts (FAE): Final report. Seattle: University of Washington school of medicine. Department of Psychiatry and behavioural sciences.

    Google Scholar 

  • Streissguth, A.P., H.M. Barr, P.D. Sampson, J.C. Parrish-Johnson, G.L. Kirchner, and D.C. Martin. 1986. Attention, distraction and reaction time at age 7 years and prenatal alcohol exposure. Neurobehavioral Toxicology and Teratology 8(6): 717–725.

    Google Scholar 

  • Streissguth, A.P., H.M. Barr, and P.D. Sampson. 1990. Moderate prenatal alcohol exposure: Effects on child IQ and learning problems at age 7½ years. Alcoholism, Clinical and Experimental Research 14(5): 662–669.

    Article  Google Scholar 

  • Streissguth, A.P., P.D. Sampson, H.C. Olson, et al. 1994. Maternal drinking during pregnancy: attention and short-term memory in 14-year-old offspring—a longitudinal prospective study. Alcoholism, Clinical and Experimental Research 18(1): 202–218.

    Article  Google Scholar 

  • Testa, M., B.M. Quigley, and R.D. Eiden. 2007. The effects of prenatal alcohol exposure on infant mental development: A meta-analytical review. Alcohol and Alcoholism 38(4): 295–304.

    Article  Google Scholar 

  • Thomsen P.H., A.M. Skovgaard. 2007. Børne- og Ungdoms psykiatri. En lærebog om børn og unges psykiske sygdomme. FADL Forlag.

    Google Scholar 

  • Underbjerg, M., U.S. Kesmodel, N.I. Landro, et al. 2012. The effects of low to moderate alcohol consumption and binge drinking in early pregnancy on selective and sustained attention in 5-year-old children. BJOG 119(10): 1211–1221.

    Article  Google Scholar 

  • Warner, R.H., and H.L. Rosett. 1975. The effects of drinking on offspring: An historical survey of the American and British literature. Journal of Studies on Alcohol 36(11): 1395–1420.

    Article  Google Scholar 

  • West, J.R. 1987. Fetal alcohol-induced brain damage and the problem of determining temporal vulnerability: A review. Alcohol and Drug Research 7(5–6): 423–441.

    Google Scholar 

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Niclasen, J. (2016). Is It Ethical to Condone Low Levels of Drinking in Pregnancy?. In: Nelson, M., Trussler, M. (eds) Fetal Alcohol Spectrum Disorders in Adults: Ethical and Legal Perspectives. International Library of Ethics, Law, and the New Medicine, vol 63. Springer, Cham. https://doi.org/10.1007/978-3-319-20866-4_5

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