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Metal Response in Cupriavidus metallidurans pp 21–44Cite as

Genomic Context of Metal Response Genes in Cupriavidus metallidurans with a Focus on Strain CH34

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Part of the book series: SpringerBriefs in Molecular Science ((SB BIOMETALS))

Abstract

Cupriavidus metallidurans CH34 has been studied for over 30 years, mostly because of its resistance to numerous heavy metals. Many of these metal resistance determinants were rapidly associated with native megaplasmids. However, its genome sequencing and whole genome expression profiling not only revealed the complex structure of its multiple replicons and complex responses to metals, but also revealed the presence of unnoticed/unstudied metal resistance determinants on the different replicons. In this chapter, the genomic context of the metal response genes in C. metallidurans CH34 will be described with a focus on its mobilome including insertion sequence elements, transposons, integrative and conjugative elements and genomic islands.

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  1. Unit of Microbiology, Belgian Nuclear Research Centre (SCK•CEN), Mol, Belgium

    Rob Van Houdt & Max Mergeay

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  1. Rob Van Houdt
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  1. Unit of Microbiology, Belgium Nuclear Research Centre, Mol, Belgium

    Max Mergeay

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    Rob Van Houdt

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Van Houdt, R., Mergeay, M. (2015). Genomic Context of Metal Response Genes in Cupriavidus metallidurans with a Focus on Strain CH34. In: Mergeay, M., Van Houdt, R. (eds) Metal Response in Cupriavidus metallidurans. SpringerBriefs in Molecular Science(). Springer, Cham. https://doi.org/10.1007/978-3-319-20594-6_2

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