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Angiographic Narrowing Prior to ST Elevation MI. Are the Lesions Non Obstructive?

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Controversies in Cardiology

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Abstract

In the 1980s, our group and others published studies that showed that myocardial infarction frequently arose from plaques that on angiograms prior to the event were not significantly stenotic. Over the years, this became an accepted tenet of cardiology and was even incorporated into the definition of the vulnerable plaque. However, more recently, other angiographic data performed either just before or immediately after infarction as well as intravascular data at the time of infarction assessing lesion severity have challenged this paradigm showing that the lesions were, in fact, severely stenotic. This chapter reviews these data and indicates how these two possibilities are actually not mutually exclusive.

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Author information

Authors and Affiliations

  1. Chief of Cardiology, UCSF Fresno, Fresno, CA, USA

    John A. Ambrose MD

  2. Department of Medicine, UCSF Community Regional Medical Center, Fresno, CA, USA

    John A. Ambrose MD

  3. UCSF Fresno Department of Cardiology, Community Regional Medical Center, Fresno, CA, USA

    Ryan Berg MD

Authors
  1. John A. Ambrose MD
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  2. Ryan Berg MD
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Corresponding author

Correspondence to Ryan Berg MD .

Editor information

Editors and Affiliations

  1. UCSF Fresno, Fresno, California, USA

    John A. Ambrose

  2. Department of Interventional Cardiology, Otamendi Hospital, Buenos Aires, Argentina

    Alfredo E. Rodríguez

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Ambrose, J.A., Berg, R. (2015). Angiographic Narrowing Prior to ST Elevation MI. Are the Lesions Non Obstructive?. In: Ambrose, J., Rodríguez, A. (eds) Controversies in Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-319-20415-4_2

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  • DOI: https://doi.org/10.1007/978-3-319-20415-4_2

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20414-7

  • Online ISBN: 978-3-319-20415-4

  • eBook Packages: MedicineMedicine (R0)

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