Fluid-Structure Interaction Model of Human Mitral Valve within Left Ventricle

  • Hao GaoEmail author
  • Nan Qi
  • Xingshuang Ma
  • Boyce E. Griffith
  • Colin Berry
  • Xiaoyu Luo
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9126)


We present an integrated model of mitral valve coupled with the left ventricle. The model is derived from clinical images and takes into account of the important valvular features, left ventricle contraction, nonlinear soft tissue mechanics, fluid structure interaction, and the MV-LV interaction. This model is compared with a corresponding mitral-tube model, and differences in the results are discussed. Although the model is a step closer towards simulating physiological realistic situation, further work is required to ensure that the highly complex valvular-ventricular interaction, and the fluid-structure interaction, can be reliably represented.


Left Ventricle Mitral Valve Cardiac Magnetic Resonance Image Left Ventricle Wall Inflow Tract 
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This work is funded by the UK EPSRC (EP/I1029990), and the British Heart Foundation (PG/14/64/31043, PG/11/2/28474). B.E.G. acknowledges research support from the American Heart Association (AHA award 10 SDG4320049), the National Institutes of Health (award HL117063), and the National Science Foundation (awards DMS 1016554 and ACI 1047734).


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Hao Gao
    • 1
    Email author
  • Nan Qi
    • 1
  • Xingshuang Ma
    • 2
  • Boyce E. Griffith
    • 3
  • Colin Berry
    • 4
  • Xiaoyu Luo
    • 1
  1. 1.School of Mathematics and StatisticsUniversity of GlasgowGlasgowUK
  2. 2.School of Aerospace EngineeringChongqing UniversityChongqingChina
  3. 3.Department of MathematicsUniversity of North CarolinaChapel HillUSA
  4. 4.Institute of Cardiovascular and Medical ScienceUniversity of GlasgowGlasgowUK

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