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Microalgal Systems Biology for Biofuel Production

  • Chapter
Algal Biorefineries

Abstract

In recent years, microalgae has received a lot of attention as potential sources of renewable energy, especially given the increase in oil prices and environmental concerns. Therefore, microalgal systems biology can shed light on complex interactions in biological systems through integration of various omics data. Genome-scale metabolic reconstruction can provide insights into cellular metabolism and species-specific adaptive features, whereas in silico analysis is a powerful tool for analysis of metabolic flux and identification of gene targets for enhanced production of biofuel precursors. Here, we highlight the current state of research in microalgal systems biology and evaluate the potential for future sustainable microalgae-based biofuel engineering and development of “green cell factories.”

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Authors and Affiliations

  1. National Marine Bioenergy Research Center, Department of Biological Engineering, Inha University, 100 Inha-Ro, Nam-Gu, Incheon, 402-751, Korea

    Seong-Joo Hong & Choul-Gyun Lee

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  1. Seong-Joo Hong
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  2. Choul-Gyun Lee
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Correspondence to Choul-Gyun Lee .

Editor information

Editors and Affiliations

  1. Department of Chemical and Biological Engineering, Vanderbilt University, Nashville, Tennessee, USA

    Aleš Prokop

  2. Department of Chemical Engineering, University of Louisiana at Lafayette, Lafayette, Louisiana, USA

    Rakesh K. Bajpai

  3. Department of Chemical Engineering, University of Louisiana at Lafayette, Lafayette, Louisiana, USA

    Mark E. Zappi

List of Abbreviations

List of Abbreviations

ACP:

Acyl carrier protein

BOF:

Biomass object function

C3:

Three-carbon

CFPP:

Cold filter plugging point

CoA:

Coenzyme A

ER:

Endoplasmic reticulum

FBA:

Flux balance analysis

GPR:

Gene-protein-reaction

HMG-CoA:

3-hydroxy-3-methylglutaryl-CoA

IPP:

Isopentenyl diphosphate

MEP:

2-C-methyl-D-erythritol 4-phosphate

MVA:

Mevalonate

PGA:

3-phosphoglyceric acid

PhPP:

Phenotype phase plane analysis

RACE:

Rapid amplification of cDNA ends

RubisCO:

Ribulose-1,5-bisphosphate carboxylase/oxygenase

TAG:

Triacylglycerol

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Hong, SJ., Lee, CG. (2015). Microalgal Systems Biology for Biofuel Production. In: Prokop, A., Bajpai, R., Zappi, M. (eds) Algal Biorefineries. Springer, Cham. https://doi.org/10.1007/978-3-319-20200-6_1

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