Abstract
This dissertation is focused on the investigation of biological mechanisms related to hIAPP. This peptide is involved in T2DM where it misfolds and subsequently aggregates within the pancreas in the form of amyloid fibrils.
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Paravastu AK, Qahwash I, Leapman RD, Meredith SC, Tycko R (2009) Seeded growth of β-amyloid fibrils from alzheimer’s brain-derived fibrils produces a distinct fibril structure. Proc Natl Acad Sci USA 106:7443–7448
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Skeby, K.K. (2016). Conclusion and Perspectives. In: Computational Modelling of the Human Islet Amyloid Polypeptide. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-20040-8_7
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DOI: https://doi.org/10.1007/978-3-319-20040-8_7
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Online ISBN: 978-3-319-20040-8
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