Abstract
Aniridic keratopathy can be seen in up to 90 % of patients. Traditionally, therapy was supportive followed by penetrating keratoplasty when stromal scarring occurred. More recently, keratolimbal allograft (KLAL) has been shown to be an effective treatment. In this chapter we discuss how to maximize the visual outcome of aniridic keratopathy patients. Glaucoma should be addressed by placing shunts in patients prior to KLAL in order to limit topical glaucoma medication in the post operative course. Aniridic keratopathy patients with deteriorating corneal surfaces should be operated on before stromal scarring occurs. Fibrin glue may be used in surgery to reduce operating time and increase patient comfort. Immunosuppression plays a vital role in maintaining the allograft without rejection and should be monitored by a transplant specialist. With correct management, donor cells have been shown to populate the corneal surface years after surgery.
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Hassan, O., Djalilian, A.R. (2015). Strategies for Success in Limbal Allograft Transplantation for Aniridia. In: Parekh, M., Poli, B., Ferrari, S., Teofili, C., Ponzin, D. (eds) Aniridia. Springer, Cham. https://doi.org/10.1007/978-3-319-19779-1_11
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DOI: https://doi.org/10.1007/978-3-319-19779-1_11
Publisher Name: Springer, Cham
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