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Postoperative Myocardial Infarction

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Abstract

A significant number of noncardiac surgical patients are at risk for postoperative myocardial infarction (PMI). PMI leads to significant mortality and morbidity and increases the health-care costs. Better understanding of perioperative surgical and patient risk factors causing PMI, understanding the disease process and presentation of PMI, newer treatment strategies, and perioperative use of beta-blockers and statins have significantly decreased the incidence of nonfatal PMI. Risk stratification, perioperative optimization of at-risk patients, and treatment of PMI are challenging and may not be the same as other myocardial infarctions.

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References

  1. Wroblewski F, LaDue JS. Myocardial infarction as a postoperative complication of major surgery. JAMA. 1952;150:1212–6.

    Article  CAS  Google Scholar 

  2. Mangano DT. Perioperative cardiac morbidity. Anesthesiology. 1990;72:153–84.

    Article  CAS  PubMed  Google Scholar 

  3. Tarhan S, Moffitt EA, Taylor WF, Giuliani ER. Myocardial infarction after general anesthesia. JAMA. 1972;220:1451–4.

    Article  CAS  PubMed  Google Scholar 

  4. Goldman L, Caldera DL, Nussbaum SR, Southwick FS, Krogstad D, Murray B, et al. Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med. 1977;297:845–50.

    Article  CAS  PubMed  Google Scholar 

  5. Ashton CM, Petersen NJ, Wray NP, Kiefe CI, Dunn JK, Wu L, et al. The incidence of perioperative myocardial infarction in men undergoing noncardiac surgery. Ann Intern Med. 1993;118:504–10.

    Article  CAS  PubMed  Google Scholar 

  6. Eagle KA, Coley CM, Newell JB, Brewster DC, Darling RC, Strauss HW, et al. Combining clinical and thallium data optimizes preoperative assessment of cardiac risk before major vascular surgery. Ann Intern Med. 1989;110:859–66.

    Article  CAS  PubMed  Google Scholar 

  7. Detsky AS, Abrams HB, McLaughlin JR, Drucker DJ, Sasson Z, Johnston N, et al. Predicting cardiac complications in patients undergoing non-cardiac surgery. J Gen Intern Med. 1986;1:211–9.

    Article  CAS  PubMed  Google Scholar 

  8. Steen PA, Tinker JH, Tarhan S. Myocardial reinfarction after anesthesia and surgery. JAMA. 1978;239:2566–70.

    Article  CAS  PubMed  Google Scholar 

  9. Rao TL, Jacobs KH, El-Etr AA. Reinfarction following anesthesia in patients with myocardial infarction. Anesthesiology. 1983;59:499–505.

    Article  CAS  PubMed  Google Scholar 

  10. Hertzer NR. Fatal myocardial infarction following peripheral vascular operations. A study of 951 patients followed 6 to 11 years postoperatively. Cleve Clin Q. 1982;49:1–11.

    Article  CAS  PubMed  Google Scholar 

  11. Hertzer NR. Basic data concerning associated coronary disease in peripheral vascular patients. Ann Vasc Surg. 1987;1:616–20.

    Article  CAS  PubMed  Google Scholar 

  12. Bartels K, Karhausen J, Clambey ET, Grenz A, Eltzschig HK. Perioperative organ injury. Anesthesiology. 2013;119:1474–89.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Nelson AH, Fleisher LA, Rosenbaum SH. Relationship between postoperative anemia and cardiac morbidity in high-risk vascular patients in the intensive care unit. Crit Care Med. 1993;21:860–6.

    Article  CAS  PubMed  Google Scholar 

  14. Chapman I. Morphogenesis of occluding coronary artery thrombosis. Arch Pathol. 1965;80:256–61.

    CAS  PubMed  Google Scholar 

  15. Constantinides P. Plaque fissures in human coronary thrombosis. J Atheroscler Res. 1966;6:1–17.

    Article  Google Scholar 

  16. Kawai C. Pathogenesis of acute myocardial infarction. Novel regulatory systems of bioactive substances in the vessel wall. Circulation. 1994;90:1033–43.

    Article  CAS  PubMed  Google Scholar 

  17. Slogoff S, Keats AS. Does perioperative myocardial ischemia lead to postoperative myocardial infarction? Anesthesiology. 1985;62:107–14.

    Article  CAS  PubMed  Google Scholar 

  18. Badner NH, Knill RL, Brown JE, Novick TV, Gelb AW. Myocardial infarction after noncardiac surgery. Anesthesiology. 1998;88:572–8.

    Article  CAS  PubMed  Google Scholar 

  19. Latham P, Joshi GP. Coronary revascularization without cardiopulmonary bypass: use of ischemic preconditioning and adenosine. Anesthesiology. 1998;88:828–30.

    Article  CAS  PubMed  Google Scholar 

  20. Stanley GD, Pierce ET, Moore WJ, Lewis KP, Bode Jr RH. Spinal anesthesia reduces oxygen consumption in diabetic patients prior to peripheral vascular surgery. Reg Anesth. 1997;22:53–8.

    Article  CAS  PubMed  Google Scholar 

  21. Westenskow DR, Jordan WS. Changes in oxygen consumption induced by fentanyl and thiopentone during balanced anaesthesia. Can Anaesth Soc J. 1978;25:18–21.

    Article  CAS  PubMed  Google Scholar 

  22. Waxman K, Lazrove S, Shoemaker WC. Physiologic responses to operation in high risk surgical patients. Surg Gynecol Obstet. 1981;152:633–8.

    CAS  PubMed  Google Scholar 

  23. Weissman C. The metabolic response to stress: an overview and update. Anesthesiology. 1990;73:308–27.

    Article  CAS  PubMed  Google Scholar 

  24. Halter JB, Pflug AE, Porte Jr D. Mechanisms of plasma catecholamine increase during surgical stress in man. J Clin Endocrinol Metab. 1977;45:936–44.

    Article  CAS  PubMed  Google Scholar 

  25. Collins Jr GJ, Barber JA, Zajtchuk R, Vanek D, Malogne LA. The effects of operative stress on the coagulation profile. Am J Surg. 1977;133:612–6.

    Article  PubMed  Google Scholar 

  26. Seyfer AE, Seaber AV, Dombrose FA, Urbaniak JRU. Coagulation changes in elective surgery and trauma. Ann Surg. 1981;193:210–3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. McDaniel MD, Pearce WH, Yao JS, Rossi EC, Fahey VA, Green D, et al. Sequential changes in coagulation and platelet function following femorotibial bypass. J Vasc Surg. 1984;1:261–8.

    Article  CAS  PubMed  Google Scholar 

  28. Reeder MK, Muir AD, Foex P, Goldman MD, Loh L, Smart D. Postoperative myocardial ischaemia: temporal association with nocturnal hypoxaemia. Br J Anaesth. 1991;67:626–31.

    Article  CAS  PubMed  Google Scholar 

  29. Reeder MK, Goldman MD, Loh L, Muir AD, Foëx P, Casey KR, et al. Postoperative hypoxaemia after major abdominal vascular surgery. Br J Anaesth. 1992;68:23–6.

    Article  CAS  PubMed  Google Scholar 

  30. Gutstein DE, Fuster V. Pathophysiology and clinical significance of atherosclerotic plaque rupture. Cardiovasc Res. 1999;41:323–33.

    Article  CAS  PubMed  Google Scholar 

  31. Ambrose JA, Weinrauch M. Thrombosis in ischemic heart disease. Arch Intern Med. 1996;156:1382–94.

    Article  CAS  PubMed  Google Scholar 

  32. Tofler GH. Triggering and the pathophysiology of acute coronary syndromes. Am Heart J. 1997;134(5 Pt 2):S55–61.

    Article  CAS  PubMed  Google Scholar 

  33. Farb A, Burke AP, Tang AL, Liang TY, Mannan P, Smialek J, et al. Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death. Circulation. 1996;93:1354–63.

    Article  CAS  PubMed  Google Scholar 

  34. Plutzky J. Atherosclerotic plaque rupture: emerging insights and opportunities. Am J Cardiol. 1999;84(1A):15J–20.

    Article  CAS  PubMed  Google Scholar 

  35. Chapman I. The initiating cause of coronary artery thrombosis: an anatomic study. J Mt Sinai Hosp NY. 1969;36:361–74.

    CAS  Google Scholar 

  36. Barger AC, Beeuwkes 3rd R. Rupture of coronary vasa vasorum as a trigger of acute myocardial infarction. Am J Cardiol. 1990;66:41G–3.

    Article  CAS  PubMed  Google Scholar 

  37. Barger AC, Beeuwkes R, Lainey LL, Silverman KJ. Hypothesis: vasa vasorum and neovascularization of human coronary arteries. A possible role in the pathophysiology of atherosclerosis. N Engl J Med. 1984;310(3):175–7.

    Article  CAS  PubMed  Google Scholar 

  38. Arbustini E, Morbini P, Bello BD, Prati F, Specchia G. From plaque biology to clinical setting. Am Heart J. 1999;138(2 Pt 2):S55–60.

    Article  CAS  PubMed  Google Scholar 

  39. Gurfinkel E, Bozovich G, Daroca A, Beck E, Mautner B. Randomised trial of roxithromycin in non-Q-wave coronary syndromes: ROXIS Pilot Study. ROXIS Study Group. Lancet. 1997;350:404–7.

    Article  CAS  PubMed  Google Scholar 

  40. Raby KE, Barry J, Creager MA, Cook EF, Weisberg MC, Goldman L. Detection and significance of intraoperative and postoperative myocardial ischemia in peripheral vascular surgery. JAMA. 1992;268:222–7.

    Article  CAS  PubMed  Google Scholar 

  41. Le Manach Y, Perel A, Coriat P, Godet G, Bertrand M, Riou B. Early and delayed myocardial infarction after abdominal aortic surgery. Anesthesiology. 2005;102:885–91.

    Article  PubMed  Google Scholar 

  42. Botto F, Alonso-Coello P, Chan MT, Villar JC, Xavier D, Srinathan S, et al. Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology. 2014;120:564–78.

    Article  PubMed  Google Scholar 

  43. Hertzer NR, Beven EG, Young JR, O’Hara PJ, Ruschhaupt 3rd WF, Graor RA, et al. Coronary artery disease in peripheral vascular patients. A classification of 1000 coronary angiograms and results of surgical management. Ann Surg. 1984;199:223–33.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  44. Poldermans D, Arnese M, Fioretti PM, Salustri A, Boersma E, Thomson IR, et al. Improved cardiac risk stratification in major vascular surgery with dobutamine-atropine stress echocardiography. J Am Coll Cardiol. 1995;26:648–53.

    Article  CAS  PubMed  Google Scholar 

  45. Detsky AS, Abrams HB, Forbath N, Scott JG, Hilliard JR. Cardiac assessment for patients undergoing noncardiac surgery. A multifactorial clinical risk index. Arch Intern Med. 1986;146:2131–4.

    Article  CAS  PubMed  Google Scholar 

  46. Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999;100:1043–9.

    Article  CAS  PubMed  Google Scholar 

  47. Landesberg G, Einav S, Christopherson R, Beattie C, Berlatzky Y, Rosenfeld B, et al. Perioperative ischemia and cardiac complications in major vascular surgery: importance of the preoperative twelve-lead electrocardiogram. J Vasc Surg. 1997;26:570–8.

    Article  CAS  PubMed  Google Scholar 

  48. Carliner NH, Fisher ML, Plotnick GD, Moran GW, Kelemen MH, Gadacz TR, et al. The preoperative electrocardiogram as an indicator of risk in major noncardiac surgery. Can J Cardiol. 1986;2:134–7.

    CAS  PubMed  Google Scholar 

  49. Gage AA, Bhayana JN, Balu V, Hook N. Assessment of cardiac risk in surgical patients. Arch Surg. 1977;112:1488–92.

    Article  CAS  PubMed  Google Scholar 

  50. Cutler BS, Wheeler HB, Paraskos JA, Cardullo PA. Applicability and interpretation of electrocardiographic stress testing in patients with peripheral vascular disease. Am J Surg. 1981;141:501–6.

    Article  CAS  PubMed  Google Scholar 

  51. Carliner NH, Fisher ML, Plotnick GD, Garbart H, Rapoport A, Kelemen MH, et al. Routine preoperative exercise testing in patients undergoing major non-cardiac surgery. Am J Cardiol. 1985;56:51–8.

    Article  CAS  PubMed  Google Scholar 

  52. Gianrossi R, Detrano R, Mulvihill D, Lehmann K, Dubach P, Colombo A, et al. Exercise-induced ST depression in the diagnosis of coronary artery disease. A meta-analysis. Circulation. 1989;80:87–98.

    Article  CAS  PubMed  Google Scholar 

  53. Raby KE, Goldman L, Creager MA, Cook EF, Weisberg MC, Whittemore AD, et al. Correlation between preoperative ischemia and major cardiac events after peripheral vascular surgery. N Engl J Med. 1989;321:1296–300.

    Article  CAS  PubMed  Google Scholar 

  54. Boucher CA, Brewster DC, Darling RC, Okada RD, Strauss HW, Pohost GM. Determination of cardiac risk by dipyridamole-thallium imaging before peripheral vascular surgery. N Engl J Med. 1985;312:389–94.

    Article  CAS  PubMed  Google Scholar 

  55. Leppo J, Plaja J, Gionet M, Tumolo J, Paraskos JA, Cutler BS. Noninvasive evaluation of cardiac risk before elective vascular surgery. J Am Coll Cardiol. 1987;9:269–76.

    Article  CAS  PubMed  Google Scholar 

  56. Lette J, Waters D, Lapointe J, Gagnon A, Picard M, Cerino M, et al. Usefulness of the severity and extent of reversible perfusion defects during thallium-dipyridamole imaging for cardiac risk assessment before noncardiac surgery. Am J Cardiol. 1989;64:276–81.

    Article  CAS  PubMed  Google Scholar 

  57. Levinson JR, Boucher CA, Coley CM, Guiney TE, Strauss HW, Eagle KA. Usefulness of semiquantitative analysis of dipyridamole-thallium-201 redistribution for improving risk stratification before vascular surgery. Am J Cardiol. 1990;66:406–10.

    Article  CAS  PubMed  Google Scholar 

  58. McEnroe CS, O’Donnell Jr RF, Yeager A, Konstam M, Mackey WC. Comparison of ejection fraction and Goldman risk factor analysis of dipyridamole-thallium 201 studies in the evaluation of cardiac morbidity after aortic aneurysm surgery. J Vasc Surg. 1990;11:497–504.

    Article  CAS  PubMed  Google Scholar 

  59. Stratmann HG, Younis LT, Wittry MD, Amato M, Mark AL, Miller DD. Dipyridamole technetium 99m sestamibi myocardial tomography for preoperative cardiac risk stratification before major or minor nonvascular surgery. Am Heart J. 1996;132:536–41.

    Article  CAS  PubMed  Google Scholar 

  60. Shaw L, Miller DD, Kong BA, Hilton T, Stelken A, Stocke K, et al. Determination of perioperative cardiac risk by adenosine thallium-201 myocardial imaging. Am Heart J. 1992;124:861–9.

    Article  CAS  PubMed  Google Scholar 

  61. Martin TW, Seaworth JF, Johns JP, Pupa LE, Condos WR. Comparison of adenosine, dipyridamole, and dobutamine in stress echocardiography. Ann Intern Med. 1992;116:190–6.

    Article  CAS  PubMed  Google Scholar 

  62. Mangano DT, London MJ, Tubau JF, Browner WS, Hollenberg M, Krupski W, et al. Dipyridamole thallium-201 scintigraphy as a preoperative screening test. A reexamination of its predictive potential. Study of Perioperative Ischemia Research Group. Circulation. 1991;84:493–502.

    Article  CAS  PubMed  Google Scholar 

  63. Vanzetto G, Machecourt J, Blendea D, Fagret D, Borrel E, Magne JL, et al. Additive value of thallium single-photon emission computed tomography myocardial imaging for prediction of perioperative events in clinically selected high cardiac risk patients having abdominal aortic surgery. Am J Cardiol. 1996;77:143–8.

    Article  CAS  PubMed  Google Scholar 

  64. Garber AM, Solomon NA. Cost-effectiveness of alternative test strategies for the diagnosis of coronary artery disease. Ann Intern Med. 1999;130:719–28.

    Article  CAS  PubMed  Google Scholar 

  65. Halm EA, Browner WS, Tubau JF, Tateo IM, Mangano DT. Echocardiography for assessing cardiac risk in patients having noncardiac surgery. Study of Perioperative Ischemia Research Group. Ann Intern Med. 1996;125:433–41.

    Article  CAS  PubMed  Google Scholar 

  66. Poldermans D, Fioretti PM, Forster T, Thomson IR, Boersma E, el-Said EM, et al. Dobutamine stress echocardiography for assessment of perioperative cardiac risk in patients undergoing major vascular surgery. Circulation. 1993;87:1506–12.

    Article  CAS  PubMed  Google Scholar 

  67. Fletcher JP, Antico VF, Gruenewald S, Kershaw LZ. Risk of aortic aneurysm surgery as assessed by preoperative gated heart pool scan. Br J Surg. 1989;76:26–8.

    Article  CAS  PubMed  Google Scholar 

  68. Mosley JG, Clarke JM, Ell PJ, Marston A. Assessment of myocardial function before aortic surgery by radionuclide angiocardiography. Br J Surg. 1985;72:886–7.

    Article  CAS  PubMed  Google Scholar 

  69. Pasternack PF, Imparato AM, Riles TS, Baumann FG, Bear G, Lamparello PJ, et al. The value of the radionuclide angiogram in the prediction of perioperative myocardial infarction in patients undergoing lower extremity revascularization procedures. Circulation. 1985;72(3 Pt 2):II13–7.

    CAS  PubMed  Google Scholar 

  70. Mantha S, Roizen MF, Barnard J, Thisted RA, Ellis JE, Foss J. Relative effectiveness of four preoperative tests for predicting adverse cardiac outcomes after vascular surgery: a meta-analysis. Anesth Analg. 1994;79:422–33.

    Article  CAS  PubMed  Google Scholar 

  71. Eagle KA, Brundage BH, Chaitman BR, Ewy GA, Fleisher LA, Hertzer NR, et al. Guidelines for perioperative cardiovascular evaluation for noncardiac surgery. Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Committee on Perioperative Cardiovascular Evaluation for Noncardiac Surgery. Circulation. 1996;93:1278–317.

    CAS  PubMed  Google Scholar 

  72. Fleisher LA, Beckman JA, Brown KA, Calkins H, Chaikof E, Fleischmann KE, et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. Circulation. 2007;116:e418–99.

    Article  PubMed  Google Scholar 

  73. American Society of Anesthesiologists Task Force on Pulmonary Artery Catheterization. Anesthesiology. Practice guidelines for pulmonary artery catheterization. A report by the American Society of Anesthesiologists Task Force on Pulmonary Artery Catheterization. Anesthesiology. 1993;78:380–94.

    Google Scholar 

  74. Muir AD, Reeder MK, Foex P, Ormerod OJ, Sear JW, Johnston C. Preoperative silent myocardial ischaemia: incidence and predictors in a general surgical population. Br J Anaesth. 1991;67:373–7.

    Article  CAS  PubMed  Google Scholar 

  75. Charlson ME, MacKenzie CR, Ales KL, Gold JP, Fairclough Jr GF, Shires GT. The post-operative electrocardiogram and creatine kinase: implications for diagnosis of myocardial infarction after non-cardiac surgery. J Clin Epidemiol. 1989;42:25–34.

    Article  CAS  PubMed  Google Scholar 

  76. Mangano DT, Browner WS, Hollenberg M, London MJ, Tubau JF, Tateo IM. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing non-cardiac surgery. The Study of Perioperative Ischemia Research Group. N Engl J Med. 1990;323:1781–8.

    Article  CAS  PubMed  Google Scholar 

  77. Alpert JS, Chipkin SR, Aronin N. Diabetes mellitus and silent myocardial ischemia. Adv Cardiol. 1990;37:297–303.

    Article  CAS  PubMed  Google Scholar 

  78. Savage RM, Wagner GS, Ideker RE, Podolsky SA, Hackel DB. Correlation of postmortem anatomic findings with electrocardiographic changes in patients with myocardial infarction: retrospective study of patients with typical anterior and posterior infarcts. Circulation. 1977;55:279–85.

    Article  CAS  PubMed  Google Scholar 

  79. Andersen PT, Moller-Petersen J, Klaerke A, Henneberg EW. Evaluation of the usefulness of enzymatic diagnosis of myocardial infarction in patients with acute arterial occlusion of the lower extremities. Acta Anaesthesiol Scand. 1987;31:38–43.

    Article  CAS  PubMed  Google Scholar 

  80. Graeber GM, Clagett GP, Wolf RE, Cafferty PJ, Harmon JW, Rich NM. Alterations in serum creatine kinase and lactate dehydrogenase. Association with abdominal aortic surgery, myocardial infarction and bowel necrosis. Chest. 1990;97:521–7.

    Article  CAS  PubMed  Google Scholar 

  81. Zimmerman J, Fromm R, Meyer D, Boudreaux A, Wun CC, Smalling R, et al. Diagnostic marker cooperative study for the diagnosis of myocardial infarction. Circulation. 1999;99:1671–7.

    Article  CAS  PubMed  Google Scholar 

  82. Ryan TJ, Antman EM, Brooks NH, Califf RM, Hillis LD, Hiratzka LF, et al. 1999 Update. ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction). J Am Coll Cardiol. 1999;34:890–911.

    Article  CAS  PubMed  Google Scholar 

  83. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet. 1988;2:349–60.

    Google Scholar 

  84. Pfeffer MA, Braunwald E, Moyé LA, Basta L, Brown Jr EJ, Cuddy TE, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med. 1992;327:669–77.

    Article  CAS  PubMed  Google Scholar 

  85. Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation. 1990;81:1161–72.

    Article  CAS  PubMed  Google Scholar 

  86. Ohman EM, George BS, White CJ, Kern MJ, Gurbel PA, Freedman RJ, et al. Use of aortic counterpulsation to improve sustained coronary artery patency during acute myocardial infarction. Results of a randomized trial. The Randomized IABP Study Group. Circulation. 1994;90:792–9.

    Article  CAS  PubMed  Google Scholar 

  87. Berlauk JF, Abrams JH, Gilmour IJ, O’Connor SR, Knighton DR, Cerra FB. Preoperative optimization of cardiovascular hemodynamics improves outcome in peripheral vascular surgery. A prospective, randomized clinical trial. Ann Surg. 1991;214:289–97.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  88. Mangano DT, Layug EL, Wallace A, Tateo I. Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery. Multicenter Study of Perioperative Ischemia Research Group. N Engl J Med. 1996;335:1713–20.

    Article  CAS  PubMed  Google Scholar 

  89. Wallace A, Layug B, Tateo I, Li J, Hollenberg M, Browner W, et al. Prophylactic atenolol reduces postoperative myocardial ischemia. McSPI Research Group. Anesthesiology. 1998;88:7–17.

    Article  CAS  PubMed  Google Scholar 

  90. Lindenauer PK, Pekow P, Wang K, Mamidi DK, Gutierrez B, Benjamin EM. Perioperative beta-blocker therapy and mortality after major noncardiac surgery. N Engl J Med. 2005;353(4):349–61.

    Article  CAS  PubMed  Google Scholar 

  91. Raby KE, Brull SJ, Timimi F, Akhtar S, Rosenbaum S, Naimi C, et al. The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. Anesth Analg. 1999;88:477–82.

    CAS  PubMed  Google Scholar 

  92. POISE Study Group, Devereaux PJ, Yang H, Yusuf S, Guyatt G, Leslie K, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008;371:1839–47.

    Article  CAS  Google Scholar 

  93. Ashes C, Judelman S, Wijeysundera DN, Tait G, Mazer CD, Hare GM, et al. Selective Beta1-antagonism with bisoprolol is associated with fewer postoperative strokes than atenolol or metoprolol: a single-center cohort study of 44,092 consecutive patients. Anesthesiology. 2013;119:777–87.

    Article  CAS  PubMed  Google Scholar 

  94. Andersson C, Mérie C, Jørgensen M, Gislason GH, Torp-Pedersen C, Overgaard C, et al. Association of blocker therapy with risks of adverse cardiovascular events and deaths in patients with ischemic heart disease undergoing noncardiac surgery. A Danish nationwide cohort study. JAMA Intern Med. 2014;174:336–44.

    Article  CAS  PubMed  Google Scholar 

  95. Fleisher LA. Perioperative beta-blockade: how best to translate evidence into practice. Anesth Analg. 2007;104:1–3.

    Article  PubMed  Google Scholar 

  96. Fleischmann KE, Beckman JA, Buller CE, Calkins H, Fleisher LA, Freeman WK, et al. 2009 ACCF/AHA focused update on perioperative beta blockade: a report of the American college of cardiology foundation/American heart association task force on practice guidelines. Circulation. 2009;120:2123–51.

    Article  PubMed  Google Scholar 

  97. Blackburn H. Standardization of the exercise electrocardiogram: a systematic comparison of chest lead configurations employed for monitoring during exercise. In: Karvonen MJ, Barry AJ, editors. Physical activity and the heart. Springfield: CC Thomas; 1967. p. 90.

    Google Scholar 

  98. American Society of Anesthesiologists and the Society of Cardiovascular Anesthesiologists Task Force on Transesophageal Echocardiography. Practice guidelines for perioperative transesophageal echocardiography. A report by the American Society of Anesthesiologists and the Society of Cardiovascular Anesthesiologists Task Force on Transesophageal Echocardiography. Anesthesiology. 1996;84:986–1006.

    Google Scholar 

  99. Dodds TM, Stone JG, Coromilas J, Weinberger M, Levy DG. Prophylactic nitroglycerin infusion during noncardiac surgery does not reduce perioperative ischemia. Anesth Analg. 1993;76:705–13.

    Article  CAS  PubMed  Google Scholar 

  100. Thomson IR, Mutch WA, Culligan JD. Failure of intravenous nitroglycerin to prevent intraoperative myocardial ischemia during fentanyl-pancuronium anesthesia. Anesthesiology. 1984;61:385–93.

    Article  CAS  PubMed  Google Scholar 

  101. Gallagher JD, Moore RA, Jose AB, Botros SB, Clark DL. Prophylactic nitroglycerin infusions during coronary artery bypass surgery. Anesthesiology. 1986;64:785–9.

    Article  CAS  PubMed  Google Scholar 

  102. Wallace AW, Galindez D, Salahieh A, Layug EL, Lazo EA, Haratonik KA, et al. Effect of clonidine on cardiovascular morbidity and mortality after noncardiac surgery. Anesthesiology. 2004;101:284–93.

    Article  CAS  PubMed  Google Scholar 

  103. Poldermans D, Bax JJ, Kertai MD, Krenning B, Westerhout CM, Schinkel AF, et al. Statins are associated with a reduced incidence of perioperative mortality in patients undergoing major noncardiac vascular surgery. Circulation. 2003;107:1848–51.

    Article  CAS  PubMed  Google Scholar 

  104. Durazzo AE, Machado FS, Ikeoka DT, De Bernoche C, Monachini MC, Puech-Leão P, et al. Reduction in cardiovascular events after vascular surgery with atorvastatin: a randomized trial. J Vasc Surg. 2004;39(5):967–75.

    Article  PubMed  Google Scholar 

  105. Le Manach Y, Coriat P, Collard CD, Riedel B. Statin therapy within the perioperative period. Anesthesiology. 2008;108:1141–6.

    Article  PubMed  Google Scholar 

  106. Hindler K, Shaw AD, Samuels J, Fulton S, Collard CD, Riedel B. Improved postoperative outcomes associated with preoperative statin therapy. Anesthesiology. 2006;105:1260–72.

    Article  CAS  PubMed  Google Scholar 

  107. Le Manach Y, Godet G, Coriat P, Martinon C, Bertrand M, Fléron MH, et al. The impact of postoperative discontinuation or continuation of chronic statin therapy on cardiac outcome after major vascular surgery. Anesth Analg. 2007;104:1326–33.

    Article  PubMed  CAS  Google Scholar 

  108. Kersten JR, Gross GJ, Pagel PS, Warltier DC. Activation of adenosine triphosphate-regulated potassium channels: mediation of cellular and organ protection. Anesthesiology. 1998;88:495–513.

    Article  CAS  PubMed  Google Scholar 

  109. Ross S, Foex P. Protective effects of anaesthetics in reversible and irreversible ischaemia-reperfusion injury. Br J Anaesth. 1999;82:622–32.

    Article  CAS  PubMed  Google Scholar 

  110. Bode Jr RH, Lewis KP, Zarich SW, Pierce ET, Roberts M, Kowalchuk GJ, et al. Cardiac outcome after peripheral vascular surgery. Comparison of general and regional anesthesia. Anesthesiology. 1996;84:3–13.

    Article  PubMed  Google Scholar 

  111. Yeager MP, Glass DD, Neff RK, Brinck-Johnsen T. Epidural anesthesia and analgesia in high-risk surgical patients. Anesthesiology. 1987;66:729–36.

    Article  CAS  PubMed  Google Scholar 

  112. Landesberg G, Shatz V, Akopnik I, Wolf YG, Mayer M, Berlatzky Y, et al. Association of cardiac troponin, CK-MB, and postoperative myocardial ischemia with long-term survival after major vascular surgery. J Am Coll Cardiol. 2003;42(9):1547–54.

    Article  CAS  PubMed  Google Scholar 

  113. McFalls EO, Ward HB, Moritz TE, Goldman S, Krupski WC, Littooy F, et al. Coronary-artery revascularization before elective major vascular surgery. N Engl J Med. 2004;351:2795–804.

    Article  CAS  PubMed  Google Scholar 

  114. Sharma AK, Ajani AE, Hamwi SM, Maniar P, Lakhani SV, Waksman R, et al. Major noncardiac surgery following coronary stenting: when is it safe to operate? Catheter Cardiovasc Interv. 2004;63:141–5.

    Article  PubMed  Google Scholar 

  115. Chassot PG, Delabays A, Spahn DR. Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction. Br J Anaesth. 2007;99:316–28.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Glynne D. Stanley MBChB, FRCA .

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Stanley, G.D., Rengasamy, S.K. (2016). Postoperative Myocardial Infarction. In: O'Donnell, J., Nácul, F. (eds) Surgical Intensive Care Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-19668-8_22

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