Abstract
Imaging plays a key role in the assessment of psoriasis. However they findings are not still adequately standardized which reduces the confidence from the clinicians on his application.
Ultrasound (US) is a promising tool for the assessment of both quantification of the disease activity and the treatment responsiveness in patients with psoriasis. The continuous technological advances in this field allowed the development of equipments provided with very sensitive power Doppler (PD), which permit a sensitive detection of blood flow even in small vessels of superficial tissues such as nail and skin.
Over the past few years, videocapillaroscopy (VCP) is also generating a great interest in the assessment of microvascular changes in psoriasis representing an emergent tool for both clinical and research approaches.
This chapter provides data about the potential role of imaging, including US and VCP, in depicting both skin and nail changes in patients with psoriasis.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Nestle FO. Psoriasis. Curr Dir Autoimmun. 2008;10:65–75.
Salaffi F, De Angelis R, Grassi W, MArche Pain Prevalence, INvestigation Group (MAPPING) Study. Prevalence of musculoskeletal conditions in an Italian population sample: results of a regional community-based study, I: the MAPPING study. Clin Exp Rheumatol. 2005;23:819–28.
Salomon J, Szepietowski JC, Proniewicz A. Psoriatic nails: a prospective clinical study. J Cutan Med Surg. 2003;7:317–21.
Feldman SR, Krueger GG. Psoriasis assessment tools in clinical trials. Ann Rheum Dis. 2005;64:1165–8.
Gupta AK, Turnbull DH, Harasiewicz KA, et al. The use of high-frequency ultrasound as a method of assessing the severity of a plaque of psoriasis. Arch Dermatol. 1996;132:658–62.
Vaillant L, Berson M, Machet L, Callens A, Pourcelot L, Lorette G. Ultrasound imaging of psoriatic skin: a noninvasive technique to evaluate treatment of psoriasis. Int J Dermatol. 1994;33:786–90.
El Gammal S, El Gammal C, Kaspar K, et al. Sonography of the skin at 100 MHz enables in vivo visualization of stratum corneum and viable epidermis in palmar skin and psoriatic plaques. J Invest Dermatol. 1999;113:821–9.
El Gammal S, Auer T, Popp C, et al. Psoriasis vulgaris in 50 MHz B-scan ultrasound: characteristic features of stratum corneum, epidermis and dermis. Acta Derm Venereol Suppl (Stockh). 1994;186:173–6.
Serup J. Non-invasive quantification of psoriatic plaque: measurement of skin thickness with 15 MHz pulsed ultrasound. Clin Exp Dermatol. 1984;9:502–8.
Olsen LO, Serup J. High-frequency ultrasound scan for noninvasive cross-sectional imaging of psoriasis. Acta Derm Venereol. 1993;73:185–7.
Creamer D, Allen MH, Sousa A, Poston R, Barker JN. Localization of endothelial proliferation and microvascular expansion in active plaque psoriasis. Br J Dermatol. 1997;136:859–65.
Rosina P, Zamperetti MR, Giovannini A, Girolomoni G. Videocapillaroscopy in the differential diagnosis between psoriasis and seborrheic dermatitis of the scalp. Dermatology. 2007;214:21–4.
Bhushan M, Moore T, Herrick AL, Griffiths CE. Nailfold video capillaroscopy in psoriasis. Br J Dermatol. 2000;142:1171–6.
Sallì L, Raimondi F, Pappalardo A. Periungual capillaroscopy in psoriatic arthritis. Clin Ter. 1999;150:409–12.
Bull RH, Bates DO, Mortimer PS. Intravital videocapillaroscopy for the study of the microcirculation in psoriasis. Br J Dermatol. 1992;126:436–45.
Trevisan G, Magaton Rizzi G, Dal Canton M. Psoriatic microangiopathy modifications induced by PUVA and etretinate therapy. A nail-fold capillary microscopic study. Acta Derm Venereol Suppl (Stockh). 1989;146:53–6.
Ribeiro CF, Siqueira EB, Holler AP, Fabrício L, Skare TL. Periungual capillaroscopy in psoriasis. An Bras Dermatol. 2012;87:550–3.
Lambova SN, Müller-Ladner U. Capillaroscopic pattern in inflammatory arthritis. Microvasc Res. 2012;83:318–22.
Hegyi J, Hegyi V, Messer G, Arenberger P, Ruzicka T, Berking C. Confocal laser-scanning capillaroscopy: a novel approach to the analysis of skin capillaries in vivo. Skin Res Technol. 2009;15:476–81.
De Angelis R, Grassi W, Cutolo M. A growing need for capillaroscopy in rheumatology. Arthritis Rheum. 2009;61:405–10.
Cutolo M, Sulli A, Pizzorni C, Smith V. Capillaroscopy as an outcome measure for clinical trials on the peripheral vasculopathy in SSc: is it useful? Int J Rheumatol 2010;2010:pii: 784947.
Herrick AL, Cutolo M. Clinical implications from capillaroscopic analysis in patients with Raynaud’s phenomenon and systemic sclerosis. Arthritis Rheum. 2010;62(2):595–604.
Di Nardo A, Seidenari S, Giannetti A. B-scanning evaluation with image analysis of psoriatic skin. Exp Dermatol. 1992;1:121–5.
Seidenari S. High-frequency sonography combined with image analysis: a noninvasive objective method for skin evaluation and description. Clin Dermatol. 1995;13:349–59.
Fornage BD, McGavran MH, Duvic M, Waldron CA. Imaging of the skin with 20-MHz US. Radiology. 1993;189:69–76.
Guastalla P, Guerci VI, Fabretto A, et al. Detection of epidermal thickening in GJB2 carriers with epidermal US. Radiology. 2009;251:280–6.
Gutierrez M, De Angelis R, Bernardini ML, et al. Clinical, power Doppler sonography and histological assessment of the psoriatic plaque: short-term monitoring in patients treated with etanercept. Br J Dermatol. 2011;164:33–7.
Gutierrez M, Di Geso L, Salaffi F, et al. Development of a preliminary US power Doppler composite score for monitoring treatment in PsA. Rheumatology. 2012;51:1261–8.
Hern S, Mortimer OS. In vivo quantification of microvessels in clinically univolved psoriatic skin and in normal skin. Br J Dermatol. 2007;156:1224–9.
Espinoza LR, Vasey FB, Espinoza GG, Bocanegra TS, Germain BF. Vascular changes in psoriatic synovium. A light and electron microscopy study. Arthritis Rheum. 1982;25:677–84.
Bhusman M, Moore T, Herrick A, Griffiths CEM. Naildfold video capillaroscopy in psoriasis. Br J Dermatol. 2000;142:1171–6.
Bartosinska J, Chodorowska G. Original proposal of capillaroscopic images classification in psoriasis vulgaris and psoriatic arthritis. Adv Dermatol Allergol. 2009;26:17.
Musumeci ML, Lacarrubba F, Fusto CM, Micali G. Combined clinical, capillaroscopic and ultrasound evaluation during treatment of plaque psoriasis with oral cyclosporine. Int J Immunopathol Pharmacol. 2013;26:1027–33.
Stinco G, Buligan C, Maione V, Valent F, Patrone P. Videocapillaroscopic findings in the microcirculation of the psoriatic plaque during etanercept therapy. Clin Exp Dermatol. 2013;38:633–7.
Rosina P, Giovannini A, Gisondi P, Girolomoni G. Microcirculatory modifications of psoriatic lesions during topical therapy. Skin Res Technol. 2009;15:135–8.
Stinco G, Lautieri S, Piccirillo F, Valent F, Patrone P. Response of cutaneous microcirculation to treatment with mometasone furoate in patients with psoriasis. Clin Exp Dermatol. 2009;34:915–9.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Gutierrez, M., Bertolazzi, C. (2016). Imaging Tools in Skin and Nail Psoriasis. In: Adebajo, A., Boehncke, WH., Gladman, D., Mease, P. (eds) Psoriatic Arthritis and Psoriasis. Springer, Cham. https://doi.org/10.1007/978-3-319-19530-8_18
Download citation
DOI: https://doi.org/10.1007/978-3-319-19530-8_18
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-19529-2
Online ISBN: 978-3-319-19530-8
eBook Packages: MedicineMedicine (R0)