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Autoimmune Thyroiditis

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Book cover Thyroid Diseases in Childhood

Abstract

The aim of this survey is to report the most recent views on epidemiology, pathophysiology, presentation patterns, evolution over time, and long-term prognosis of Hashimoto’s thyroiditis (HT) in childhood and adolescence.

The main aspects that have been examined in detail are those concerning the interrelations between HT and Graves’ disease and the role played by Down syndrome and Turner syndrome in conditioning an increased susceptibility to HT.

We have also carefully considered the relationships between presentation patterns of HT and its evolution over time and the risk factors for malignancy in the children with HT-related nodular disease.

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Abbreviations

DS:

Down’s syndrome

HT:

Hashimoto’s thyroiditis

US:

Ultrasonographic

FNAC:

fine-needle-aspiration cytology

GD:

Graves’ disease

TS:

Turner syndrome

Htx:

Hashitoxicosis

TG:

Thyroglobulin

TSH:

Thyrotropin

TGAb:

TG-autoantibodies

TRAb:

TSH receptor autoantibodies

L-T4:

Levothyroxine

TPOAb:

Thyroid peroxidase autoantibodies

SH:

Subclinical hypothyroidism

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Authors and Affiliations

  1. Department of Pediatric, Gynecological, Microbiological and Biomedical Sciences, University of Messina, Via Consolare Valeria, Messina, 98125, Italy

    Filippo De Luca MD, Tommaso Aversa MD, PhD, Giuseppina Salzano MD, PhD, Giuseppina Zirilli MD, PhD, Concetta Sferlazzas MD & Malgorzata Wasniewska MD, PhD

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  1. Filippo De Luca MD
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  2. Tommaso Aversa MD, PhD
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  3. Giuseppina Salzano MD, PhD
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  4. Giuseppina Zirilli MD, PhD
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  5. Concetta Sferlazzas MD
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  6. Malgorzata Wasniewska MD, PhD
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Correspondence to Filippo De Luca MD .

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Editors and Affiliations

  1. Novara, Italy

    Gianni Bona

  2. Messina, Italy

    Filippo De Luca

  3. Division of Pediatrics, Piedemonte Hospital, Novara, Italy

    Alice Monzani

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De Luca, F., Aversa, T., Salzano, G., Zirilli, G., Sferlazzas, C., Wasniewska, M. (2015). Autoimmune Thyroiditis. In: Bona, G., De Luca, F., Monzani, A. (eds) Thyroid Diseases in Childhood. Springer, Cham. https://doi.org/10.1007/978-3-319-19213-0_16

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  • DOI: https://doi.org/10.1007/978-3-319-19213-0_16

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