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Antitumor Essential Oils: Progress in Medicinal Chemistry

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Bioactive Essential Oils and Cancer

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Abstract

A few examples of in silico design, synthesis, and antitumor activity of essential oils compounds and derivatives are found in the literature. Essential oils exhibit moderate to low cytotoxicity; therefore, chemical modifications on their constituents have been proposed with the goal to increase the antitumor activity. This chapter introduces successful examples of the use of medicinal chemistry tools applied to essential oils constituents focusing on antitumor activity.

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Author information

Authors and Affiliations

  1. Department of Pharmacy, Federal University of Sergipe, 49100-000, São Cristóvão, Brazil

    Sócrates Cabral de Holanda Cavalcanti

  2. Department of Pharmacy, Federal University of Sergipe, 58051-970, São Cristóvão, Brazil

    Rafael dos Reis Barreto de Oliveira

  3. Department of Pharmaceutical Sciences, Federal University of Paraíba, 58051-970, João Pessoa, Brazil

    Damião Pergentino de Sousa

Authors
  1. Sócrates Cabral de Holanda Cavalcanti
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  2. Rafael dos Reis Barreto de Oliveira
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  3. Damião Pergentino de Sousa
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Correspondence to Sócrates Cabral de Holanda Cavalcanti .

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Editors and Affiliations

  1. Federal University of Paraiba, João Pessoa, Paraíba, Brazil

    Damião Pergentino de Sousa

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de Holanda Cavalcanti, S., de Oliveira, R., de Sousa, D. (2015). Antitumor Essential Oils: Progress in Medicinal Chemistry. In: de Sousa, D. (eds) Bioactive Essential Oils and Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-19144-7_5

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