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Secondary Lipofilling After Breast Reconstruction with Implants

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Breast Reconstruction

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Abstract

Lipofilling has been used since many years and becomes rapidly popular especially in Plastic Surgery as it is a low-cost, low-morbidity and easy to perform procedure. Nowadays, a great field of application is Breast Reconstructive Surgery, in which it can be used as ancillary surgery to improve symmetry and final cosmetic result in mastectomy, but it can also to give better aesthetical results in the conservative treatment, particularly in case of defect resulting from tumor resection followed by the radiotherapy. The structural fat grafting technique focused on centrifugation properties described by Coleman is the most frequently and safely used, and most of the time, ensures a good root of the graft. Many authors have documented the protective and therapeutic effect of the injected fat against the dangerous consequence of radiotherapy on the reconstructed breast. Indeed, it is well demonstrated that when performed during radiation therapy (RT) lipotransfer, thanks to adipose tissue’s proprieties, is able to reduce the risk of capsular contracture, tissues ulceration and consequently of implant exposure as it provides a major thickness of the tissue above the implant.

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References

  1. Van der Meulen (1889) Cited by Billings E, May JW. Historical review and present status of free fat graft autotransplantation in plastic and reconstructive surgery. Plast Reconstr Surg 1989;83(2):368–381

    Google Scholar 

  2. Neuber G (1893) Cited by Billings E, May JW. Historical review and present status of free fat graft autotransplantation in plastic and reconstructive surgery. Plast Reconstr Surg 1989;83(2):368–381

    Google Scholar 

  3. Roddi R, Riggio E, Gilbert PM (1994) The value of microfat injection “Lipofilling” in the treatment of soft tissue deformities of the face in Parry-Romberg syndrome. Eur J Plast Surg 17(2):79–83

    Article  Google Scholar 

  4. Riggio E, Bordoni D, Nava M (2013) Oncologic surveillance of breast cancer patients after lipofilling. Aesthetic Plast Surg 37(4):728–735

    Article  PubMed  Google Scholar 

  5. Asken S (1988) Facial liposuction and microlipoinjection. J Dermatol Surg Oncol 14(3):297–305

    Article  CAS  PubMed  Google Scholar 

  6. Shiffman MA (2001) History of autologous fat transfer. In: Shiffman MA (ed) Autologous fat transplantation. Marcel Dekker, New York, pp 1–3

    Google Scholar 

  7. Bruning P (1914) Cited by Broeckaert TJ, Steinhaus J. Contribution e l’etude des greffes adipueses. Bull Acad Roy Med Belgique 28:440

    Google Scholar 

  8. Teimourian B, Fisher JB (1981) Suction curettage to remove excess fat for body contouring. Plast Reconstr Surg 68(1):50–58

    Article  CAS  PubMed  Google Scholar 

  9. Illouz YG (1983) Body contouring by lipolysis: a 5-year experience with over 3,000 cases. Plast Reconstr Surg 72(5):591–597

    Article  CAS  PubMed  Google Scholar 

  10. Cigna E, Ribuffo D, Sorvillo V, Atzeni M, Piperno A, Calò PG, Scuderi N (2012) Secondary lipofilling after breast reconstruction with implants. Eur Rev Med Pharmacol Sci 16(12):1729–1734

    CAS  PubMed  Google Scholar 

  11. Coleman SR (1995) Long-term survival of fat transplants: controller demonstrations. Aesthetic Plast Surg 19(5):421–425

    Article  CAS  PubMed  Google Scholar 

  12. Klein JA (1999) Anesthetic formulation of tumescent solutions. Dermatol Clin 17(4):751–759

    Article  CAS  PubMed  Google Scholar 

  13. Lohsiriwat V, Curigliano G, Rietjens M, Goldhrisch A, Petit JY (2011) Autologous fat transplantation in patients with breast cancer: “silencing” or “fueling” cancer recurrence? The Breast 20(4):351–357

    Article  PubMed  Google Scholar 

  14. Costantino A, Fioramonti P, Ciotti M, Onesti MG (2012) Lipofilling in skin affected by radiodermatitis: clinical and ultrasound aspects. Case report. G Chir 33(5):186–190

    CAS  PubMed  Google Scholar 

  15. Rigotti G, Marchi A, Galie M, Baroni G, Benati D, Krampera M, Pasini A, Sbarbati A (2007) Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derivated adult stem cells. Plast Reconstr Surg 119(5):1409–1422

    Article  CAS  PubMed  Google Scholar 

  16. Petit JY, Botteri E, Lohsiriwat V, Rietjens M, De Lorenzi F, Garusi C, Rossetto F, Martella S, Manconi A, Bertolini F, Curigliano G, Veronesi P, Santilo B, Rotmensz N (2012) Locoregional recurrence risk after lipofilling in breast cancer patients. Ann Oncol 23(3):582–588

    Article  CAS  PubMed  Google Scholar 

  17. Ahima RS, Flier JS (2000) Adipose tissue a san endocrine organ. Trends Endocrinol Met 11(8):327–332

    Article  CAS  Google Scholar 

  18. Kim S, Moustaid-Moussa N (2000) Secretory, endocrine and autocrine/paracrine function of the adipocyte. J Nutr 130(12):3110S–3115S

    CAS  PubMed  Google Scholar 

  19. Montrescu ER, Rio MC (2008) Cancer cells, adipocytes and matrix metalloproteinase 11: a vicious tumor progression cycle. Biol Chem 389(8):1037–1041

    Google Scholar 

  20. Mantzoros C, Petridou E, Dessypris N, Chavelas C, Dalamaga M, Alexe DM, Papadiamantis Y, Markopoulos C, Spanos E, Chrousos G, Trichopoulos D (2004) Adiponectin and breast cancer risk. J Clin Endocrinol Metab 89(3):1041–1048

    Google Scholar 

  21. Kang JH, Lee YY, Yu BY, Yang BS, Cho KH, Yoon DK, Roh YK (2005) Adiponectin induces growth arrest and apoptosis of MDA-MB-231 breast cancer cell. Arch Pharm Res 28(11):1263–1269

    Article  CAS  PubMed  Google Scholar 

  22. Ribuffo D, Atzeni M, Serratore F, Guerra M, Bucher S (2011) Cagliari University Hospital (CUH) protocol for immediate allo plastic breast reconstruction and unplanned radiotherapy. A preliminary report. Eur Rev Med Pharmacol Sci 15(7):840–844

    CAS  PubMed  Google Scholar 

  23. Scuderi N, Rubino C (2004) Chirurgia Plastica, 2nd edn. Piccin, Padova, pp 226–231

    Google Scholar 

  24. Ribuffo D, Atzeni M, Guerra M, Bucher S, Politi C, Deidda M, Atzori F, Dessi M, Madeddu C, Lay G (2013) Treatment of Irradiated expanders: protective lipofilling allows immediate prosthetic breast reconstruction in the setting of postoperative radiotherapy. Aesthetic Plast Surg 37(6):1146–1152

    Article  PubMed  Google Scholar 

  25. Ragaz J, Olivotto IA, Spinelli JJ, Phillips N, Jackson SM, Wilson KS, Knowling MA, Coppin CM, Weir L, Gelmon K, Le N, Durand R, Coldman AJ, Manji M (2005) Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-years results of the British Columbia randomized trial. J Natl Cancer Inst 97(2):116–126

    Article  PubMed  Google Scholar 

  26. Overgaard M, Jensen MB, Overgaard J, Hansen PS, Rose C, Andersson M, Kamby C, Kjaer M, Gadeberg CC, Rasmussen BB, Blichert-Toft M, Mouridsen HT (1999) Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Lancet 353(9165):1641–1648

    Article  CAS  PubMed  Google Scholar 

  27. Whelan TJ, Olivotto I, Ackerman I, Chapman JW, Chua B, Nabid A, Vallis KA, White JR, Rousseau P, Fortin A, Pierce LJ, Manchul L, Craighead P, Nolan MC, Bowen J, McCready DR, Pritchard KI, Levine MN, Parulekar W (2011) NCIG-CTG MA-20: an intergroup trial of regional nodal irradiation in breast cancer. In: Abstract presented at annual meeting of American Society of Clinical Oncology, Chicago, 3–7 June, 2011

    Google Scholar 

  28. Missana MC, Laurent I, Barreau L, Balleyguier C (2007) Autologous fat transfer in reconstructive breast surgery: indication, technique and results. Eur J Surg Oncol 33(6):685–690

    Article  CAS  PubMed  Google Scholar 

  29. Kronowitz SJ, Robb GL (2009) Radiation therapy and breast reconstruction: a critical review of literature. Plast Reconstr Surg 124(2):395–408

    Article  CAS  PubMed  Google Scholar 

  30. Kronowitz SJ (2012) Current status of autologous tissue-based breast reconstruction in patients receiving postmastectomy radiation therapy. Plast Reconstr Surg 130(2):282–292

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  31. Cordeiro PG, Pusic AL, Disa JJ, McCormick B, VanZee K (2004) Irradiation after immediate tissue expander/implant breast reconstruction: outcomes, complications, aesthetic results, and satisfaction among 156 patients. Plast Reconstr Surg 113(3):877–881

    Article  PubMed  Google Scholar 

  32. Cordeiro PG (2012) Discussion. Current status of implant-based breast reconstruction in patients receiving postmastectomy radiation therapy. Plast Reconstr Surg 130(4):524e–525e

    Article  CAS  PubMed  Google Scholar 

  33. Serra-Renom JM, Munoz-Olmo JL, Serra-Mestre JM (2010) Fat grafting in postmastectomy breast reconstruction with expanders and prostheses in patients who have received radiotherapy: formation of new subcutaneous tissue. Plast Reconstr Surg 125(1):12–18

    Article  CAS  PubMed  Google Scholar 

  34. Spear SL, Wilson HB (2005) Fat injection to correct contour deformities in the reconstructed breast. In: Spear S, Wiley SC, Robb GL (eds) Surgery of the breast: principles and art. Lippincott Williams & Wilkins, Philadelphia, pp 930–946

    Google Scholar 

  35. Enajat M, Smith M, Rozen WM, Hartman EH, Liss A, Kildal M, Audolfsson T, Acosta R (2010) Aesthetic refinements and reoperative procedures following 370 consecutive DIEP and SIEA flap breast reconstructions: important considerations for patient consent. Aesthetic Plast Surg 34(3):306–312

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Plastic Surgery Unit, Department of Surgery, Sapienza University of Rome, Viale del Policlinico, 155, Rome, 00161, Italy

    Emanuele Cigna M.D., Ph.D.

  2. Unit of Plastic, Reconstructive and Aesthetic Surgery, Department of Surgery, University “Sapienza” Rome, University of Rome, Viale del Policlinico, 155, Rome, 00161, Italy

    Ambra Monfrecola M.D.

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  1. Emanuele Cigna M.D., Ph.D.
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Correspondence to Emanuele Cigna M.D., Ph.D. .

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  1. Tustin, California, USA

    Melvin A. Shiffman

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Cigna, E., Monfrecola, A. (2016). Secondary Lipofilling After Breast Reconstruction with Implants. In: Shiffman, M. (eds) Breast Reconstruction. Springer, Cham. https://doi.org/10.1007/978-3-319-18726-6_27

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  • DOI: https://doi.org/10.1007/978-3-319-18726-6_27

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-18725-9

  • Online ISBN: 978-3-319-18726-6

  • eBook Packages: MedicineMedicine (R0)

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