Abstract
A 50-year-old woman visited the Primary Care clinic for evaluation of dry, scaly, pruritic lesions on her arms and legs that had a history of spontaneously bleeding. After referral to Dermatology, the lesions were biopsied and found to be basal cell carcinoma. Basal cell carcinoma (BCC) is the most common form of non-melanoma skin cancer. BCC tends to affect older, fair-skinned individuals who have a history of intermittent intense sun exposure, and sun exposure in early life. BCC typically presents as dry, scaly, erythematous plaques, which can be highly pruritic and spontaneously bleed. Following diagnostic confirmation by tissue biopsy, BCC may be treated with cryosurgery, topical chemotherapy, excision, or Mohs micrographic surgery.
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References
Rubin AI, Chen EH, Ratner D. Basal-cell carcinoma. N Engl J Med. 2005;353(21):2262–9.
Carucci JA, Leffell DJ, Pettersen JS. Chapter 115. Basal cell carcinoma. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, editors. Fitzpatrick’s dermatology in general medicine. 8th ed. New York: McGraw-Hill; 2012. p. 1294–303.
de Vries E, Micallef R, Brewster DH, Gibbs JH, Flohil SC, Saksela O, Sankila R, Forrest AD, Trakatelli M, Coebergh JW, Proby CM, EPIDERM Group. Population-based estimates of the occurrence of multiple vs first primary basal cell carcinomas in 4 European regions. Arch Dermatol. 2012;148(3):347–54.
Xiang F, Lucas R, Hales S, Neale R. Incidence of nonmelanoma skin cancer in relation to ambient UV radiation in white populations, 1978–2012. JAMA Dermatol. 2014;150(10):1063–71.
Madan V, Lear JT, Szeimies RM. Non-melanoma skin cancer. Lancet. 2010;375(9715):673–85.
Yosipovitch G, Mills KC, Nattkemper LA, Feneran A, Tey HL, Lowenthal BM, Pearce DJ, Williford PM, Sangueza OP, D’Agostino Jr RB. Association of pain and itch with depth of invasion and inflammatory cell constitution in skin cancer: results of a large clinicopathologic study. JAMA Dermatol. 2014;150(11):1160–6.
Ramachandran S, Fryer AA, Smith A, Lear J, Bowers B, Jones PW, Strange RC. Cutaneous basal cell carcinomas: distinct host factors are associated with the development of tumors on the trunk and on the head and neck. Cancer. 2001;92(2):354–8.
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Reich, D., Psomadakis, C.E., Buka, B. (2017). Basal Cell Carcinoma. In: Top 50 Dermatology Case Studies for Primary Care. Springer, Cham. https://doi.org/10.1007/978-3-319-18627-6_7
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DOI: https://doi.org/10.1007/978-3-319-18627-6_7
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