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Neuropsychiatry of Neuromyelitis Optica

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Neuropsychiatric Symptoms of Inflammatory Demyelinating Diseases

Part of the book series: Neuropsychiatric Symptoms of Neurological Disease ((NSND))

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Abstract

Neuromyelitis optica (NMO), also called Devic’s disease, is a central nervous system inflammatory disease characterized by optic neuritis and longitudinally extensive acute transverse myelitis but also with brain involvement. Cognitive impairment is present in 54–57 % of patients. The main cognitive deficits are in long-term memory, speed of information processing, attention, and executive functions. The neural basis of cognitive troubles in NMO seems to be the whole WM but particularly the corpus callosum and the superior longitudinal fascicles. Depression and fatigue are frequent behavioral symptoms of NMO. Guidelines for the treatment of neuropsychological symptoms of NMO are needed: when clinical trials will be conducted in NMO patients, a neuropsychological evaluation will be necessary.

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Authors and Affiliations

  1. CMRR (Memory Resources and Research Centre), University Hospital of Strasbourg, 1, avenue Molière, 67000, Strasbourg, France

    Frédéric Blanc MD, PhD, HdR

  2. University of Strasbourg and CNRS, ICube Laboratory UMR 7357 and FMTS (Fédération de Médecine Translationnelle de Strasbourg), Team IMIS/Neurocrypto, Strasbourg, France

    Frédéric Blanc MD, PhD, HdR

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  1. Frédéric Blanc MD, PhD, HdR
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Correspondence to Frédéric Blanc MD, PhD, HdR .

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Editors and Affiliations

  1. Department of Neurology, Centre Hospitalier Universitaire Pellegrin, INSERM U 862, Université de Bordeaux, Bordeaux, Gironde, France

    Bruno Brochet

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Blanc, F. (2015). Neuropsychiatry of Neuromyelitis Optica. In: Brochet, B. (eds) Neuropsychiatric Symptoms of Inflammatory Demyelinating Diseases. Neuropsychiatric Symptoms of Neurological Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-18464-7_17

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  • DOI: https://doi.org/10.1007/978-3-319-18464-7_17

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-18463-0

  • Online ISBN: 978-3-319-18464-7

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