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Ocular Manifestations of Craniofacial Disorders

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Book cover The Eye in Pediatric Systemic Disease

Abstract

Congenital craniofacial anomalies are secondary to skull or soft tissue maldevelopment. Congenital skull developmental abnormalities may occur due to premature fusion of the calvarial or skull base sutures, termed craniosynostosis. Craniosynostosis can be further divided into syndromic and nonsyndromic. Syndromic craniosynostosis often involves more than one calvarial suture and has a genetic etiology, while nonsyndromic craniosynostosis often involves a single isolated suture and has no genetic etiology. Soft tissue maldevelopment can be divided into clefting and branchial arch disorders. Sequelae to the ophthalmic and visual system may occur in patients with congenital craniofacial anomalies. These sequelae may include ptosis, exorbitism, tear drainage abnormalities, corneal exposure, corneal infection, strabismus, abnormal extraocular muscles, papilledema, optic atrophy and decreased vision secondary to high refractive errors, amblyopia, and optic nerve disease.

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Authors and Affiliations

  1. Department of Surgery, Baylor College of Medicine, Texas Children’s Hospital, 6701 Fannin Street, Suite 610.00, Houston, TX, 77030, USA

    Edward P. Buchanan M.D. & Amy S. Xue M.D.

  2. Department of Pediatrics, Craniofacial Center, Seattle Children’s Hospital, Seattle, WA, USA

    Emily R. Gallagher M.D., M.P.H.

  3. Department of Pediatric Ophthalmology and Ocular Genetics, Wills Eye Hospital, Philadelphia, PA, USA

    Kara C. LaMattina M.D.

  4. Department of Ophthalmology, Baylor College of Medicine, Texas Children’s Hospital, 6701 Fannin Street, Suite 610.25, Houston, TX, 77030, USA

    Veeral S. Shah M.D., Ph.D. & Jane C. Edmond M.D.

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  1. Edward P. Buchanan M.D.
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  3. Kara C. LaMattina M.D.
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Correspondence to Jane C. Edmond M.D. .

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  1. Pediatric Ophthalmology and Ocular Genetics Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

    Alex V. Levin

  2. Department of Ophthalmology, University of Colorado School of Medicine Children’s Hospital Colorado Anschutz Medical Campus, Aurora, Colorado, USA

    Robert W. Enzenauer

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Buchanan, E.P., Gallagher, E.R., LaMattina, K.C., Shah, V.S., Xue, A.S., Edmond, J.C. (2017). Ocular Manifestations of Craniofacial Disorders. In: Levin, A., Enzenauer, R. (eds) The Eye in Pediatric Systemic Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-18389-3_7

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