Skip to main content
SpringerLink
Log in

Disorders of the Adrenal Gland

  • Chapter
Pediatric Endocrinology

  • 2206 Accesses

Abstract

Disorders of the adrenal gland can lead to effects as disparate as abnormal sexual differentiation, decreased or increased growth velocity, and life-threatening endocrine emergencies. Diseases can arise from abnormalities within the adrenal gland itself, from abnormalities in the control of the adrenal gland, or from the ingestion of exogenous steroid compounds, even if these are prescribed for the appropriate treatment of diseases. This chapter does not discuss congenital adrenal hyperplasia which is found in Chap. 8.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Suggested Reading

  1. Brandon DD, Isabelle LM, Samuels MH, Kendall JW, Loriaux DL. Cortisol production rate measurement by stable isotope dilution using gas chromatography-negative ion chemical ionization mass spectrometry. Steroids. 1999;64(6):372–8.

    Article  CAS  PubMed  Google Scholar 

  2. Martucci VL, Pacak K. Pheochromocytoma and paraganglioma: diagnosis, genetics, management, and treatment. Curr Probl Cancer. 2014;38(1):7–41.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Miller WL, Flück CE. Chapter 13 - Adrenal cortex and its disorders. In: Sperling MA, editor. Pediatric endocrinology. 4th ed. Philadelphia, PA: Elsevier; 2014. p. 471–532.

    Google Scholar 

  4. Miller WL. Steroid hormone synthesis in mitochondria. Mol Cell Endocrinol. 2013;379(1-2):62–73.

    Article  CAS  PubMed  Google Scholar 

  5. Speiser PW, Azziz R, Baskin LS, Ghizzoni L, Hensle TW, Merke DP, Meyer-Bahlburg HF, Miller WL, Montori VM, Oberfield SE, Ritzen M, White PC. Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2010;95(9):4133–60.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Santos L. Stress response in critical illness. Curr Probl Pediatr Adolesc Health Care. 2013;43(10):264–72.

    Article  PubMed  Google Scholar 

  7. Charmandari E, Kino T, Chrousos GP. Primary generalized familial and sporadic glucocorticoid resistance (Chrousos syndrome) and hypersensitivity. Endocr Dev. 2013;24:67–85.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Stratakis CA. Cushing syndrome in pediatrics. Endocrinol Metab Clin North Am. 2012;41(4):793–803.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Simonetti GD, Mohaupt MG, Bianchetti MG. Monogenic forms of hypertension. Eur J Pediatr. 2012;171(10):1433–9.

    Article  CAS  PubMed  Google Scholar 

  10. Auchus RJ. The physiology and biochemistry of adrenarche. Endocr Dev. 2011;20:20–7.

    CAS  PubMed  Google Scholar 

  11. Brown RJ, Kelly MH, Collins MT. Cushing syndrome in the McCune-Albright syndrome. J Clin Endocrinol Metab. 2010;95(4):1508–15.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Vehaskari VM. Heritable forms of hypertension. Pediatr Nephrol. 2009;24(10):1929–37.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Oskis A, Loveday C, Hucklebridge F, Thorn L, Clow A. Diurnal patterns of salivary cortisol across the adolescent period in healthy females. Psychoneuroendocrinology. 2009;34(3):307–16.

    Article  CAS  PubMed  Google Scholar 

  14. Waguespack SG, Ying AK. Chapter 14 - Pheochromocytoma and multiple endocrine neoplasia syndromes. In: Sperling MA, editor. Pediatric endocrinology. 4th ed. Philadelphia, PA: Elsevier; 2014. p. 533–568.

    Google Scholar 

  15. Monticone S, Auchus RJ, Rainey WE. Adrenal disorders in pregnancy. Nat Rev Endocrinol. 2012;8(11):668–78.

    Article  CAS  PubMed  Google Scholar 

  16. Moisiadis VG, Matthews SG. Glucocorticoids and fetal programming part 2: mechanisms. Nat Rev Endocrinol. 2014;10(7):403–11.

    Article  CAS  PubMed  Google Scholar 

  17. Moisiadis VG, Matthews SG. Glucocorticoids and fetal programming part 1: outcomes. Nat Rev Endocrinol. 2014;10(7):391–402.

    Article  CAS  PubMed  Google Scholar 

  18. Miller WL, Witchel SF. Prenatal treatment of congenital adrenal hyperplasia: risks outweigh benefits. Am J Obstet Gynecol. 2013;208(5):354–9.

    Article  PubMed  Google Scholar 

  19. Gamble KL, Berry R, Frank SJ, Young ME. Circadian clock control of endocrine factors. Nat Rev Endocrinol. 2014;10(8):466–75.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Nieman LK, Biller BM, Findling JW, Murad MH, Newell-Price J, Savage MO, Tabarin A; Endocrine Society. Treatment of Cushing’s Syndrome: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2015;100(8):2807–31.

    Google Scholar 

  21. Donohoue P. Diagnosis of adrenal insufficiency in children. http://www.uptodate.com/contents/diagnosis-of-adrenal-insufficiency-in-children.

  22. Donohoue P. Causes and clinical manifestations of primary adrenal insufficiency in children. http://www.uptodate.com/contents/causes-and-clinical-manifestations-of-primary-adrenal-insufficiency-in-children.

  23. Donohoue P. Treatment of adrenal insufficiency in children http://www.uptodate.com/contents/treatment-of-adrenal-insufficiency-in-children.

  24. Donohoue P. Causes and clinical manifestations of central adrenal insufficiency in children http://www.uptodate.com/contents/causes-and-clinical-manifestations-of-central-adrenal-insufficiency-in-children

  25. Auron M, Raissouni N. Adrenal insufficiency. Pediatr Rev. 2015;36(3):92–102.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University of California Davis School of Medicine, Sacramento, CA, USA

    Dennis M. Styne (Pediatrics)

Authors
  1. Dennis M. Styne
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Styne, D.M. (2016). Disorders of the Adrenal Gland. In: Pediatric Endocrinology. Springer, Cham. https://doi.org/10.1007/978-3-319-18371-8_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-18371-8_10

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-18370-1

  • Online ISBN: 978-3-319-18371-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation