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Life Extension pp 229–244Cite as

Life-Extending Effect of Phytochemicals in Drosophila

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Part of the book series: Healthy Ageing and Longevity ((HAL,volume 3))

Abstract

Plant-derived compounds known as phytochemicals have attracted the attention of biologists as well as the general public for their ability to improve quality and quantity of life. Several phytochemicals have been found to exert beneficial effects in this regard, including inhibition of aging and extending the life spans of experimental animals such as yeast, worms, flies, and mice. Drosophila melanogaster is a particularly effective model system for evaluating anti-aging compounds. This insect is suitable for aging research since it has a rapid generation time and short life span. In this chapter, we review typical phytochemicals such as resveratrol, curcumin, and catechin that extend the life span of Drosophila melanogaster as well as discuss the molecular mechanisms underlying this effect.

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Acknowledgments

This work was supported by LG Yonam Foundation Professors’ Oversea Research Program.

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Authors and Affiliations

  1. Department of Biological Sciences, Inha University, Incheon, 402-751, South Korea

    Lee Shin-Hae & Min Kyung-Jin

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  1. Lee Shin-Hae
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  2. Min Kyung-Jin
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Correspondence to Min Kyung-Jin .

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Editors and Affiliations

  1. Laboratory of Epigenetics, Institute of Gerontology, Kiev, Kievs'ka, Ukraine

    Alexander M. Vaiserman

  2. Laboratory of Molecular Radiobiology and Gerontology, Institute of Biology of Komi Science Center of Ural Branch of RAS, Syktyvkar, Komi Republic, Russia

    Alexey A. Moskalev

  3. Laboratory of Genome Variation, Institute of Molecular Genetics of RAS, Moscow, Russia

    Elena G. Pasyukova

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Shin-Hae, L., Kyung-Jin, M. (2015). Life-Extending Effect of Phytochemicals in Drosophila . In: Vaiserman, A., Moskalev, A., Pasyukova, E. (eds) Life Extension. Healthy Ageing and Longevity, vol 3. Springer, Cham. https://doi.org/10.1007/978-3-319-18326-8_10

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