Abstract
Oesophageal cancer is the eighth most common cancer, accounting for nearly 460,000 (3 %) new cancer cases globally, and 80 % of these occur in less developed countries. Treatment modalities include surgery, radiotherapy, chemotherapy or some combination of these; however, long-term survival remains poor regardless of method of treatment with 5-year-average survival rate of only 5–17 %. Most of the patients presenting in low resource settings present with advanced disease and are unfit for curative treatment of a combined neoadjuvant chemoradiotherapy and surgery which offers long-term survival in some patients. These patients may however have an improved quality of life from well-planned palliative interventions that provide symptomatic relief resulting in a sensation of well-being, improved nutritional status and sometimes prolongation of life.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Lin Y, Totsuka Y, He Y, Kikuchi S, Qiao Y, Ueda J, Wei W, Inoue M, Tanaka H (2013) Epidemiology of esophageal cancer in Japan and China. J Epidemiol 23(4):233–242
Mao WM, Zheng WH, Ling ZQ (2011) Epidemiologic risk factors for esophageal cancer development. Asian Pac J Cancer Prev 12:2461–2466
Zhang Y (2013) Epidemiology of esophageal cancer. World J Gastroenterol 19(34):5598–5606
GLOBOCAN 2012
el-Serag HB (2002) The epidemic of esophageal adenocarcinoma. Gastroenterol Clin North Am 31(2):421–440
Chen W, Zheng R, Zhang S, Zeng H, Fan Y, Qiao Y, Zhou Q (2014) Esophageal cancer incidence and mortality in China, 2010. Thoracic Cancer 5(4):343–348
Liu S, Dai JY, Yao L, Li X, Reid B, Self S, Ma J, Chang Y, Feng S, de Dieu Tapsoba J, Sun X, Sun X (2014) Esophageal adenocarcinoma and its rare association with Barrett’s esophagus in Henan, China. PLoS One 9(10), e110348
Choi J, Kim SG, Kim JS, Jung HC, Song IS (2010) Comparison of endoscopic ultrasonography (EUS), positron emission tomography (PET), and computed tomography (CT) in the preoperative locoregional staging of resectable esophageal cancer. Surg Endosc 24(6):1380–1386
Siewert JR, Stein HJ, Feith M, Bruecher BL, Bartels H, Fink U (2001) Histologic tumor type is an independent prognostic parameter in esophageal cancer: lessons from more than 1,000 consecutive resections at a single center in the Western world. Ann Surg 234(3):360–369
American Joint Committee on Cancer (AJCC) staging manual, 7th edn, 2010
Cooper JS, Guo MD, Herskovic A, Macdonald JS, Martenson JA Jr, Al-Sarraf M, Byhardt R, Russell AH, Beitler JJ, Spencer S, Asbell SO, Graham MV, Leichman LL (1999) Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85–01). Radiation Therapy Oncology Group. JAMA 281(17):1623–1627
Shridhar R, Almhanna K, Meredith KL, Biagioli MC, Chuong MD, Cruz A, Hoffe SE (2013) Radiation therapy and esophageal cancer. Cancer Control 20(2):97–110
Nguyen NP, Jang S, Vock J, Vinh-Hung V, Chi A, Vos P, Pugh J, Vo RS, Ceizyk M, Desai A, Smith-Rymond L, International Geriatric Radiotherapy Group (2014) Feasibility of intensity and image guided radiotherapy for locally advanced oesophageal cancers. BMC Cancer 14:265
Gao XS, Qiao X, Wu F, Cao L, Meng X, Dong Z, Wang X, Gao G, Wu TT, Komaki R, Chang JY (2007) Pathological analysis of clinical target volume margin for radiotherapy in patients with esophageal and gastroesophageal junction carcinoma. Int J Radiat Oncol Biol Phys 67:389–396
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) (2014) Esophageal and esophageal gastric junction cancers, pp 1–125. www.nccn.org/professionals/physician_gls/f_guidelines.asp
Diamantes T, Aywyn MM (2005) Oesophageal intubation for advanced oesophageal cancer: the Baragwanath experience 1977–1981. Br J Surg 70(9):555–557
World Health Organisation. Cancer pain relief with a guide to opioid availability, 2nd edn. WHO Press. http://whqlibdoc.who.int/publications/9241544821.pdf
National Consensus Project for Quality Palliative Care (2013) Clinical practice guidelines for quality palliative care, 3rd edn. http://www.hpna.org/multimedia/NCP_Clinical_Practice_Guidelines_3rd_Edition.pdf
Kigula Mugambe JB, Kavuma A, Luutu I (2014) Palliative radiotherapy in cancer of the oesophagus – is it effective? The Mulago experience. Proceedings of the AFROG 2014 conference. www.theafrog/afrog2014/abstracts
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Kigula-Mugambe, J.B., Kavuma, A. (2015). Cancer of the Oesophagus. In: Droz, JP., Carme, B., Couppié, P., Nacher, M., Thiéblemont, C. (eds) Tropical Hemato-Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-18257-5_31
Download citation
DOI: https://doi.org/10.1007/978-3-319-18257-5_31
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-18256-8
Online ISBN: 978-3-319-18257-5
eBook Packages: MedicineMedicine (R0)