Abstract
The resulting experimental data of performed investigations on both the PED, and WDN of metal electrodes allow us to consider the possibility of using those and others in various fields of scientific research. These areas are primarily biology, medicine, and ecology . Solvents play important role in formation of three-dimensional structure and functioning of biological macromolecules. At the same time, most common methods of analysis, such as atomic force microscopy and transmission electron microscopy, are often require at sample preparation of applying it to surface, which can significantly effects on sample properties. It should be noted that single-component solutions of biomacromolecules are extremely rare in vivo, while many methods of investigation require of one-component solutions of macromolecules after chromatographic purification, i.e. at such experiments considerable part of information about the behavior of molecules functioning in their natural environment is lost. Using of the WDN in medicine based on their properties to kill a wide range of pathogenic microorganisms and spores of opportunistic to human fungal cultures. In addition, in oncology can be used the property of WDN to retard the growth of malignant tumors. The possible use of PED themselves in virology based on the impact of shock waves generated during discharges in water on the shell of viruses that can allow to prepare anti-virus vaccines. Cytostatic effect was confirmed by a significant growth suppression, cytodystrophic changes, and fibrosis of transplanted Pliss lymphosarcoma in the rats that received regular intravenous injections of WDN. The role of silver atoms in the stabilization of molecular structure of DNA, inhibition of tumor growth and/or reversion of the malignant phenotype requires further studying at tissue, cellular, and molecular levels.
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Kolikov, V., Rutberg, P. (2015). Application of the PED and WDN. In: Pulsed Electrical Discharges for Medicine and Biology. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-18129-5_10
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DOI: https://doi.org/10.1007/978-3-319-18129-5_10
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