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Fluid Mechanics and Transport in Tumors

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Physical Sciences and Engineering Advances in Life Sciences and Oncology

Part of the book series: Science Policy Reports ((SCIPOLICY))

Abstract

The physical structure of a tumor is determined by “solid,” structural components such as actin and collagen, but most of its volume is fluid. Fluid flows through the blood vessels and bathes the extravascular tissue. The structural microenvironment of a solid tumor plays a role in tumor physiology by compartmentalizing tissues and providing a dynamic substrate to support cell migration and differentiation (see Chaps. 3 and 4), but the fluid phase is equally important.

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Authors and Affiliations

  1. Massachusetts General Hospital/Harvard Medical School, Charlestown, MA, USA

    Lance L. Munn

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  1. Lance L. Munn
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Correspondence to Lance L. Munn .

Editor information

Editors and Affiliations

  1. Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Paul Janmey

  2. Bioengineering, University of California, Berkeley, California, USA

    Daniel Fletcher

  3. Department of Chemical and Biomolecular Engineering, JH Physical Sciences-Oncology Center, Institute for NanoBioTechnology, John Hopkins University, Baltimore, Maryland, USA

    Sharon Gerecht

  4. Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York City, New York, USA

    Ross Levine

  5. Cancer Institute, School of Medicine, Stanford University, Stanford, California, USA

    Parag Mallick

  6. Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon, USA

    Owen McCarty

  7. Radiation Oncology Edwin L. Steele Lab for Tumor Biology, Harvard Medical School, Charlestown, Massachusetts, USA

    Lance Munn

  8. Department of Biomedical Engineering, Cornell Univesity, Ithaca, New York, USA

    Cynthia Reinhart-King

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Munn, L.L. (2016). Fluid Mechanics and Transport in Tumors. In: Janmey, P., et al. Physical Sciences and Engineering Advances in Life Sciences and Oncology. Science Policy Reports. Springer, Cham. https://doi.org/10.1007/978-3-319-17930-8_5

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