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Abstract

Diffuse fatty infiltration is a common imaging finding due to the abnormal accumulation of lipids within hepatocytes. Baseline US is typically the first imaging modality for the evaluation of hepatic steatosis, but causing a conspicuous increase in liver echogenicity and a marked ultrasound beam attenuation, it really hampers FLL detection and characterization. Moreover, geographic fatty changes of the liver can occur when the fat accumulation ability of hepatocytes or fat deposition becomes heterogeneous throughout the liver and are classified into four subtypes: (a) focal fatty change, (b) multifocal steatosis, (c) lobar or segmental steatosis, and (d) focal fatty sparing in fatty liver [1].

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References

  1. Shiozawa K, Watanabe M, Ikehara T, Kogame M, Shinohara M, Shinohara M et al (2014) Evaluation of hemodynamics in focal steatosis and focal spared lesion of the liver using contrast-enhanced ultrasonography with sonazoid. Radiol Res Pract: 604594. doi:10.1155/2014/604594

  2. Janica J, Ustymowicz A, Lukasiewicz A et al (2013) Comparison of contrast-enhanced ultrasonography with grey-scale ultrasonography and contrast-enhanced computed tomography in diagnosing focal fatty liver infiltrations and focal fatty sparing. Adv Med Sci 58:408–418

    Article  CAS  PubMed  Google Scholar 

  3. Konopke R, Bunk A, Kersting S (2008) Contrast-enhanced ultrasonography in patients with colorectal liver metastases after chemotherapy. Ultraschall Med 29(Suppl 4):S203–S209

    Article  PubMed  Google Scholar 

  4. Mainenti PP, Mancini M, Mainolfi C et al (2010) Detection of colo-rectal liver metastases: prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1.5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents. Abdom Imaging 35:511–521

    Article  PubMed  Google Scholar 

  5. Rafaelsen SR, Jakobsen A (2011) Contrast-enhanced ultrasound vs multidetector-computed tomography for detecting liver metastases in colorectal cancer: a prospective, blinded, patient-by-patient analysis. Colorectal Dis 13:420–425

    Article  CAS  PubMed  Google Scholar 

  6. Nicolau C, Ripollés T (2012) Contrast-enhanced ultrasound in abdominal imaging. Abdom Imaging 37:1–19

    Article  PubMed  Google Scholar 

  7. Larsen LP, Rosenkilde M, Christensen H et al (2009) Can contrast-enhanced ultrasonography replace multidetector-computed tomography in the detection of liver metastases from colorectal cancer? Eur J Radiol 69:308–313

    Article  PubMed  Google Scholar 

  8. Muhi A, Ichikawa T, Motosugi U et al (2011) Diagnosis of colorectal hepatic metastases: comparison of contrast-enhanced CT, contrast-enhanced US, superparamagnetic iron oxide-enhanced MRI, and gadoxetic acid-enhanced MRI. J Magn Reson Imaging 34:326–335

    Article  PubMed  Google Scholar 

  9. Cabassa P, Bipat S, Longaretti L et al (2010) Liver metastases: sulphur hexafluoride-enhanced ultrasonography for lesion detection: a systematic review. Ultrasound Med Biol 36:1561–1567

    Article  PubMed  Google Scholar 

  10. Claudon M, Dietrich CF, Choi BI, Cosgrove DO, Kudo M, Nolsøe CP et al (2013) Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) in the liver – update 2012. A WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. Ultraschall Med 34:11–29

    CAS  PubMed  Google Scholar 

  11. Bartolotta TV, Taibbi A, Galia M, Runza G, Matranga D, Midiri M, Lagalla R (2007) Characterization of hypoechoic focal hepatic lesions in patients with fatty liver: diagnostic performance and confidence of contrast-enhanced ultrasound. Eur Radiol 17(3):650–661

    Google Scholar 

  12. Bartolotta TV, Midiri M, Scialpi M, Sciarrino E, Galia M, Lagalla R (2004) Focal nodular hyperplasia in normal and fatty liver: a qualitative and quantitative evaluation with contrast-enhanced ultrasound. Eur Radiol 14(4):583–591

    Google Scholar 

Focal Fatty Change

  1. Bartolotta TV, Taibbi A, Midiri M, Lagalla R (2009) Focal liver lesions:contrast-enhanced ultrasound. Abdom Imaging 34(2):193–209

    Article  PubMed  Google Scholar 

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Bartolotta, T.V., Taibbi, A., Midiri, M. (2015). Fatty Liver, Pseudolesions. In: Atlas of Contrast-enhanced Sonography of Focal Liver Lesions. Springer, Cham. https://doi.org/10.1007/978-3-319-17539-3_4

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  • DOI: https://doi.org/10.1007/978-3-319-17539-3_4

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17538-6

  • Online ISBN: 978-3-319-17539-3

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