Skip to main content

Abstract

Thanks to the most recent technological innovations, the ability of grayscale ultrasound (US) in the detection of focal liver lesions (FLLs) has significantly improved, even if small or deeply located. However, the characterization remains a challenge even for experienced sonographers except for hemangiomas with typical US appearance detected in patients with no history of malignancy or chronic liver disease [1].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bartolotta TV, Taibbi A, Midiri M, Matranga D, Solbiati L, Lagalla R (2011) Indeterminate focal liver lesions incidentally discovered at gray-scale US: role of contrast-enhanced sonography. Invest Radiol 46(2):106–115

    Article  PubMed  Google Scholar 

  2. Malhi H, Grant EG, Duddalwar V (2014) Contrast-enhanced ultrasound of the liver and kidney. Radiol Clin North Am 52(6):1177–1190

    Article  PubMed  Google Scholar 

  3. Cantisani V, Grazhdani H, Fioravanti C, Rosignuolo M, Calliada F, Messineo D, Bernieri MG, Redler A, Catalano C, D’Ambrosio F (2014) Liver metastases: contrast-enhanced ultrasound compared with computed tomography and magnetic resonance. World J Gastroenterol 20(29):9998–10007

    Article  PubMed Central  PubMed  Google Scholar 

  4. Bartolotta TV, Taibbi A, Midiri M, De Maria M (2008) Hepatocellular cancer response to radiofrequency tumor ablation: contrast-enhanced ultrasound. Abdom Imaging 33(5):501–511

    Article  PubMed  Google Scholar 

  5. Bartolotta TV, Taibbi A, Matranga D, Midiri M, Lagalla R (2015) 3D versus 2D contrast-enhanced sonography in the evaluation of therapeutic response of hepatocellular carcinoma after locoregional therapies: preliminary findings. Radiol Med [Epub ahead of print]

    Google Scholar 

  6. Burns PN, Wilson SR (2007) Focal liver masses: enhancement patterns on contrast-enhanced images—concordance of US scans with CT scans and MR images. Radiology 242:162–174

    Article  PubMed  Google Scholar 

  7. Piscaglia F, Bolondi L, Italian Society for Ultrasound in Medicine and Biology (SIUMB) Study Group on Ultrasound Contrast Agents (2006) The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations. Ultrasound Med Biol 32(9):1369–1375

    Article  PubMed  Google Scholar 

  8. Skyba DM, Price RJ, Linka AZ, Skalak TC, Kaul S (1998) Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue. Circulation 98(4):290–293

    Article  CAS  PubMed  Google Scholar 

  9. Claudon M, Dietrich CF, Choi BI, Cosgrove DO, Kudo M, Nolsøe CP, Piscaglia F, Wilson SR, Barr RG, Chammas MC, Chaubal NG, Chen M-H, Clevert DA, Correas JM, Ding H, Forsberg F, Fowlkes JB, Gibson RN, Goldberg BB, Lassau N, Leen ELS, Mattrey RF, Moriyasu F, Solbiati L, Weskott H-P, Xu H-X (2013) Guidelines and good clinical practice recommendations for Contrast Enhanced Ultrasound (CEUS) in the liver – update 2012. A WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. Ultrasound Med Biol 39(2):187–210

    Article  PubMed  Google Scholar 

  10. Main ML, Goldman JH, Grayburn PA (2009) Ultrasound contrast agents: balancing safety versus efficacy. Expert Opin Drug Saf 8:49–56

    Article  CAS  PubMed  Google Scholar 

  11. Main ML, Ryan AC, Davis TE et al (2008) Acute mortality in hospitalized patients undergoing echocardiography with and without an ultrasound contrast agent (multicenter registry results in 4,300,966 consecutive patients). Am J Cardiol 102:1742–1746

    Article  PubMed  Google Scholar 

  12. Coleman JL, Navid F, Furman WL, McCarville MB (2014) Safety of ultrasound contrast agents in the pediatric oncologic population: a single-institution experience. AJR Am J Roentgenol 202(5):966–970

    Article  PubMed Central  PubMed  Google Scholar 

  13. Schreiber-Dietrich DG, Cui XW, Piscaglia F, Gilja OH, Dietrich CF (2014) Contrast enhanced ultrasound in pediatric patients: a real challenge. Z Gastroenterol 52(10):1178–1184

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Bartolotta, T.V., Taibbi, A., Midiri, M. (2015). Introduction. In: Atlas of Contrast-enhanced Sonography of Focal Liver Lesions. Springer, Cham. https://doi.org/10.1007/978-3-319-17539-3_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-17539-3_1

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17538-6

  • Online ISBN: 978-3-319-17539-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics