Abstract
Surface modification approaches can be mainly regarded as by either a physical or a chemical means (note the biological ones are considered as a subset of chemical ones), or both. This chapter focuses on the physical means, particularly, a morphological approach to surface modification. Through illustration of how the area of a planar surface can be increased significantly by adding nanoscopic structures to the surface and that most of these nanostructures may be deemed useless for biosensor applications, it argues for a particular need of biosensors, namely, the need for aqua-robust nanostructures having the highest exposed surface area possible. Following that, it presents with full technical detail the processes to form aqua-robust nanopillar structures along with brief discussions on the underlying science. All the discussions are in the form of case studies, thus providing a practical guide for readers who might want to develop similar surfaces. This chapter ends with, again, a detailed discussion of a recently patented procedure on how to form integrated micro and nano structures on-a-chip for possible biosensor applications.
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Xu, X., Zhang, S., Chen, H., Kong, J.: Integration of electrochemistry in micro-total analysis systems for biochemical assays: recent developments. Talanta 80(1), 8–18 (1009)
Pumera, M., Escarpa, A.: Nanomaterials as electrochemical detectors in microfluidics and CE: fundamentals, designs, and applications. Electrophoresis 30(19), 3315–3323 (2009)
Dunn, B., Long, J.W., Rolison, D.R.: Rethinking multifunction in three dimensions for miniaturizing electrical energy storage. Electrochem. Soc. Interface 17, 49 (2008)
Zhang, G.: Design and fabrication of 3D skyscraper nanostructures and their applciations in biosensors, in new perspectives in biosensors technology and applications. In-Tech. pp. 269–290 (2011)
Lau, K.K.S., Bico, J., Teo, K.B.K., Chhowalla, M., Amaratunga, G.A.J., Milne, W.I.: Superhydrophobic carbon nanotube forests. Nano Lett. 3(12), 1701–1705 (2003)
Fan, J., Dyer, D., Zhang, G., Zhao, Y.: Nanocarpet effect: pattern formation during the wetting of vertically aligned nanorod arrays. Nano Lett. 4(11), 2133–2138 (2004)
Xu, J., Huang, X., Xie, G.: Study on the structures and magnetic properties of Ni, Co-Al2O3 electrodeposited nanowire arrays. Mater. Res. Bull. 39, 811–818 (2004)
Kralchevsky, P.A., Nagayama, K.: Capillary interactions between particles bound to interfaces, liquid films and biomembranes. Adv. Colloid Interf. Sci. 85, 145–192 (2000)
Anandan, V., Yang, X., Kim, E., Rao, Y., Zhang, G.: Role of reaction kinetics and mass transport in glucose sensing with nanopillar array electrodes. J. Biol. Eng. 1(1), 5 (2007)
Rao, Y., Anandan, V., Zhang, G.: FFT analysis of pore pattern in anodized alumina formed at various conditions. J. Nanosci. Nanotechnol. 5(12), 2070–2075 (2005)
Anandan, V., Rao, Y., Zhang, G.: Nanopillar array structures for high performance electrochemical sensing. Int. J. Nanomed. 1, 73–79 (2006)
Tanaka, Y., Sato, K., Shimizu, T., Yamato, M., Okano, T., Kitamori, T.: Biological cells on microchips: new technologies and applications. Biosens. Bioelectron. 23(4), 449–458 (2007)
Zhang, G.: United State Patent US 8,453,319 B2
Zhang, G.: United State Patent US 8,865,402 B2
Zhao, G., Xu, C., Li, H.: Highly ordered cobalt-manganese oxide (CMO) nanowire array thin film on Ti/Si substrate as an electrode for electrochemical capacitor. J. Power Sources 163(2), 1132–1136 (2007)
Balakrishman, S., Kripesh, V., Chong, S.: Fabrication of self-organized metal nanowire array using porous alumina template for off-chip interconnects. Int. J. Nanosci. 4(4), 453–458 (2006)
Rabin, O., Herz, P.R., Lin, Y., Akinwande, A.I., Cronin, S.B., Dresselhaus, M.S.: Formation of thick porous anodic alumina films and nanowire arrays on silicon wafers and glass. Adv. Funct. Mater. 13(8), 631–638 (2003)
Chu, S.Z., Wada, K., Inoue, S., Todoroki, S.: Fabrication and characteristics of nanostructures on glass by Al anodization and electrodeposition. Electrochim. Acta 48(20–22), 3147–3153 (2003)
Sharma, G., Chong, S.C., Ebin, L., Hui, C., Gan, C.L., Kripesh, V.: Fabrication of patterned and non-patterned metallic nanowire arrays on silicon substrate. Thin Solid Films 515(7–8), 3315–3322 (2007)
Hoogvliet, J.C., van Bennekom, W.P.: Gold thin-film electrodes: an EQCM study of the influence of chromium and titanium adhesion layers on the response. Electrochim. Acta 47(4), 599–611 (2001)
Gangadharan, R., Anandan, V., Zhang, A., Drwiega, J.C., Zhang, G.: Enhancing the performance of a fluidic glucose biosensor with 3D electrodes. Sensors Actuators B 160(1), 991–998 (2011)
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Zhang, G. (2015). Morphological Surface Modification. In: Nanoscale Surface Modification for Enhanced Biosensing. Springer, Cham. https://doi.org/10.1007/978-3-319-17479-2_2
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DOI: https://doi.org/10.1007/978-3-319-17479-2_2
Publisher Name: Springer, Cham
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