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Acute Kidney Injury in Pregnancy

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Acute Nephrology for the Critical Care Physician

Abstract

Pregnancy related Acute Kidney Injury (AKI) is a usual clinical challenge involving two patients. The incidence has declined over the last decades, however, peripartum AKI remains associated with substantial maternal and fetal morbidity and mortality. Physiological changes hamper normal laboratory testing. Timing of onset during the pregnancy may help in diagnosing the syndrome causing AKI: during the first trimester causes include hyperemesis gravidarum or hemorrhage. Later in pregnancy AKI is predominantly caused by preeclampsia/HELLP, thrombotic microangiopathies, acute fatty liver of pregnancy, and renal cortical necrosis related to infection, urinary tract obstruction, or nephrolithiasis. Care for pregnant women with AKI requires a multidisciplinary approach due to its association with higher risk for maternal and fetal morbidity and mortality.

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Authors and Affiliations

  1. Department of Intensive Care, University Medical Center Utrecht, 85500, Utrecht, 3508 GA, The Netherlands

    Marjel van Dam MD

  2. Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada

    Sean M. Bagshaw MD MSc

Authors
  1. Marjel van Dam MD
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Correspondence to Marjel van Dam MD .

Editor information

Editors and Affiliations

  1. Department of Intensive Care, VU University Hospital, Amsterdam, The Netherlands

    Heleen M. Oudemans-van Straaten

  2. Department of Intensive Care Medicine, Anaesthesia Critical Care Collaborative, Research Group (SPACeR) and Faculty of Health Care Sciences, Royal Surrey County Hospital NHS, Foundation Trust, Surrey Perioperative, University of Surrey, Guildford, United Kingdom

    Lui G. Forni

  3. Department of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands

    A.B. Johan Groeneveld

  4. Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

    Sean M. Bagshaw

  5. Division of Intensive Care and Emergency Medicine, Department of General Internal Medicine, Medical University Innsbruck, Anichstrasse, Innsbruck, Austria

    Michael Joannidis

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van Dam, M., Bagshaw, S.M. (2015). Acute Kidney Injury in Pregnancy. In: Oudemans-van Straaten, H., Forni, L., Groeneveld, A., Bagshaw, S., Joannidis, M. (eds) Acute Nephrology for the Critical Care Physician. Springer, Cham. https://doi.org/10.1007/978-3-319-17389-4_7

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  • DOI: https://doi.org/10.1007/978-3-319-17389-4_7

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17388-7

  • Online ISBN: 978-3-319-17389-4

  • eBook Packages: MedicineMedicine (R0)

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