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Pediatric CRRT

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Acute Nephrology for the Critical Care Physician

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Abstract

Treatment of severe acute kidney injury (AKI) is currently the prescription of renal replacement therapy (RRT). Continuous renal replacement therapy (CRRT) and peritoneal dialysis (PD) are the preferred forms of dialysis delivery in critically ill children. The prospective pediatric CRRT registry (ppCRRT) has provided several precious epidemiologic information on this field: incidence of pediatric CRRT is about 5 % in the overall pediatric population and mortality is about 60 %. Mortality is significantly associated with age, the presence of multiple organ dysfunction syndrome, and the amount of fluid overload accumulated by children before the CRRT inception. However, several aspects still remain to be further evaluated such as timing and dose of CRRT. Another important aspect of pediatric CRRT is the technical aspect: accuracy of novel CRRT monitors has greatly improved in recent years and several dedicated circuits have been developed. The next future is expected to further improve research, delivery, and outcome of pediatric CRRT especially after the introduction into the market of a new dialysis machine dedicated to neonates with the promise of extending and anticipating dialysis start in this particularly fragile portion of pediatric patients.

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Author information

Authors and Affiliations

  1. Pediatric Cardiac Intensive Care Unit, Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children’s Hospital, IRCCS, Piazza S. Onofrio 4, Rome, 00165, Italy

    Zaccaria Ricci MD

  2. Division of Nephrology, Center for Acute Care Nephrology, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, MLC 7022, Cincinnati, OH, 45206, USA

    Stuart L. Goldstein MD

Authors
  1. Zaccaria Ricci MD
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  2. Stuart L. Goldstein MD
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Corresponding author

Correspondence to Zaccaria Ricci MD .

Editor information

Editors and Affiliations

  1. Department of Intensive Care, VU University Hospital, Amsterdam, The Netherlands

    Heleen M. Oudemans-van Straaten

  2. Department of Intensive Care Medicine, Anaesthesia Critical Care Collaborative, Research Group (SPACeR) and Faculty of Health Care Sciences, Royal Surrey County Hospital NHS, Foundation Trust, Surrey Perioperative, University of Surrey, Guildford, United Kingdom

    Lui G. Forni

  3. Department of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands

    A.B. Johan Groeneveld

  4. Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

    Sean M. Bagshaw

  5. Division of Intensive Care and Emergency Medicine, Department of General Internal Medicine, Medical University Innsbruck, Anichstrasse, Innsbruck, Austria

    Michael Joannidis

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© 2015 Springer International Publishing

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Ricci, Z., Goldstein, S.L. (2015). Pediatric CRRT. In: Oudemans-van Straaten, H., Forni, L., Groeneveld, A., Bagshaw, S., Joannidis, M. (eds) Acute Nephrology for the Critical Care Physician. Springer, Cham. https://doi.org/10.1007/978-3-319-17389-4_20

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  • DOI: https://doi.org/10.1007/978-3-319-17389-4_20

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17388-7

  • Online ISBN: 978-3-319-17389-4

  • eBook Packages: MedicineMedicine (R0)

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