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Renal Replacement Therapy for Intoxications

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Book cover Acute Nephrology for the Critical Care Physician

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Abstract

Intoxications are common in emergency medicine. Most of these intoxications involve analgesics, sedatives and cardiovascular drugs. Enhanced elimination of the toxic agent is one of the cornerstones of the management of the intoxicated patient. The use of renal replacement therapy to remove a toxin is justified if there is an indication of severe toxicity and if the total body elimination of the toxin can be increased by 30% or more using this technique. Whether removal of toxins by means of renal replacement therapy is possible, depends on characteristics of the toxin itself and of the elimination technique used. In this chapter, we will give an overview of the indications and techniques for the elimination of toxic agents.

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Author information

Authors and Affiliations

  1. Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    Anne-Cornélie J. M. de Pont

Authors
  1. Anne-Cornélie J. M. de Pont
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Correspondence to Anne-Cornélie J. M. de Pont .

Editor information

Editors and Affiliations

  1. Department of Intensive Care, VU University Hospital, Amsterdam, The Netherlands

    Heleen M. Oudemans-van Straaten

  2. Department of Intensive Care Medicine, Anaesthesia Critical Care Collaborative, Research Group (SPACeR) and Faculty of Health Care Sciences, Royal Surrey County Hospital NHS, Foundation Trust, Surrey Perioperative, University of Surrey, Guildford, United Kingdom

    Lui G. Forni

  3. Department of Intensive Care, Erasmus Medical Center, Rotterdam, The Netherlands

    A.B. Johan Groeneveld

  4. Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada

    Sean M. Bagshaw

  5. Division of Intensive Care and Emergency Medicine, Department of General Internal Medicine, Medical University Innsbruck, Anichstrasse, Innsbruck, Austria

    Michael Joannidis

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de Pont, AC.J.M. (2015). Renal Replacement Therapy for Intoxications. In: Oudemans-van Straaten, H., Forni, L., Groeneveld, A., Bagshaw, S., Joannidis, M. (eds) Acute Nephrology for the Critical Care Physician. Springer, Cham. https://doi.org/10.1007/978-3-319-17389-4_19

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  • DOI: https://doi.org/10.1007/978-3-319-17389-4_19

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-17388-7

  • Online ISBN: 978-3-319-17389-4

  • eBook Packages: MedicineMedicine (R0)

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