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Modification of Polymer Surfaces for Biofunctionalization

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Design of Polymeric Platforms for Selective Biorecognition

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Abstract

The present chapter provides a collection of the protocols that have been involved in surface chemical derivatization of polymeric materials designed for immobilization of molecules involved in a biorecognition event. The introduction of primary reactive groups at the surface of initially non-reactive materials is discussed and split into two sections: wet chemical methods and physical “dry” methods. Further substrate functionalization is then described according to the type of primary reactive group present at the surface after initial treatment. Specific features such as reversibility or spatial control are highlighted.

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Authors and Affiliations

  1. Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany

    Guillaume Delaittre

  2. Institute for Chemical Technology and Polymer Chemistry, Karlsruhe Institute of Technology, Engesserstrasse 18, 76131, Karlsruhe, Germany

    Guillaume Delaittre

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  1. Institute of Polymer Science &Technology, Madrid, Spain

    Juan Rodríguez-Hernández

  2. IMDEA Nanociencia and CNB-CSIC-IMDEA Nanociencia Associated Unit “Unidad Nanobiotecnología”, Madrid, Spain

    Aitziber L. Cortajarena

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Delaittre, G. (2015). Modification of Polymer Surfaces for Biofunctionalization. In: Rodríguez-Hernández, J., Cortajarena, A. (eds) Design of Polymeric Platforms for Selective Biorecognition. Springer, Cham. https://doi.org/10.1007/978-3-319-17061-9_4

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