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Abstract

Chronic rhinosinusitis (CRS) represents one of the most common healthcare problems in the United States, afflicting approximately 31 million Americans (National Center for Health Statistics. National ambulatory medical care survey 1990–1995. Hyattsville: US Public Health Service. Series 13 [CD-ROM], 1997). CRS is a clinical syndrome associated with persistent inflammation of the mucosa of the nose and paranasal sinuses for 12 weeks or longer (Fokkens et al, Rhinol Suppl 50:1–299, 2012; Meltzer and Hamilos, Mayo Clin Proc 86:427–443, 2011). It is known to cause significant physical impairment, adversely impacting patient quality of life and psychosocial well-being. Despite its prevalence, CRS remains a challenging and, at times, controversial disease entity. The etiologic mechanisms of CRS continue to be a source of much debate, and as such, different schools of thought exist on the optimal management strategy. The purpose of this chapter is to describe the different proposed pathophysiologic mechanisms of CRS, with a focus on the microbiology associated with CRS.

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Correspondence to R. Peter Manes MD, FACS .

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Manes, R.P. (2015). Microbiology of Chronic Rhinosinusitis. In: Batra, P., Han, J. (eds) Practical Medical and Surgical Management of Chronic Rhinosinusitis. Springer, Cham. https://doi.org/10.1007/978-3-319-16724-4_2

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  • DOI: https://doi.org/10.1007/978-3-319-16724-4_2

  • Publisher Name: Springer, Cham

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