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Introduction

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Mitochondrial Function In Vivo Evaluated by NADH Fluorescence

Abstract

Disturbances of mitochondrial function lead to disruption of cellular activities, inducing various human diseases such as neurodegenerative processes, aging, cancer, apoptosis, and sepsis. The implications of mitochondrial dysfunction in other body pathologies are widely documented. Most of the information on mitochondrial function was accumulated by running in vitro studies. A relatively small portion of published papers were concerned with monitoring mitochondrial function in vivo and in real time.

The aim of this book is to review the field of mitochondrial monitoring in vivo using NADH autofluorescence. Also, other physiological parameters at the tissue level are measured together with mitochondrial NADH.

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Authors and Affiliations

  1. Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel

    Avraham Mayevsky

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Mayevsky, A. (2015). Introduction. In: Mitochondrial Function In Vivo Evaluated by NADH Fluorescence. Springer, Cham. https://doi.org/10.1007/978-3-319-16682-7_1

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