Abstract
Obesity, defined by the World Health Organization (WHO) as a BMI >30 kg/m2, is considered an epidemic in the United States and is estimated to afflict >20% of the population with nearly 11.5 million people affected nationwide (Demaria and Jamal, Gastroenterol Clin N Am 34(1):127–142, 2005). The population of overweight individuals (BMI between 25 and 30 kg/m2) is likewise increasing with as many as 40 million people affected. In fact, recent analysis would suggest that approximately two-thirds of the US population is overweight or obese (Yang and Colditz, JAMA Intern Med 175:1412–1413, 2015). Worldwide there has been an exponential increase in obesity with some countries reporting a near tripling of the rate of the obese population. The association between obesity and urolithiasis is well studied, and obesity has been demonstrated to be an independent risk factor for stone disease. This chapter will aim to describe the association between overweight/obesity and biochemical characteristics associated with stone disease in this particular group of individuals. We will also discuss nutritional therapies that decrease the risk of stone recurrence, improve 24-h urinary parameters, and are utilized to decrease weight and improve other comorbidities associated with the obese/overweight patient.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Demaria EJ, Jamal MK. Surgical options for obesity. Gastroenterol Clin N Am. [Comparative Study Review]. 2005;34(1):127–42.
Yang L, Colditz GA. Prevalence of overweight and obesity in the United States, 2007–2012. JAMA Intern Med. 2015;175:1412–3.
Swinburn BA, Caterson I, Seidell JC, James WP. Diet, nutrition and the prevention of excess weight gain and obesity. Public Health Nutr. 2004 Feb;7(1A):123–46.
Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH. The disease burden associated with overweight and obesity. JAMA. [Research Support, Non-U.S. Gov’t]. 1999;282(16):1523–9.
Popkin BM. The nutrition transition and obesity in the developing world. J Nutr. [Review]. 2001;131(3):871S–3S.
Taylor EN, Stampfer MJ, Curhan GC. Obesity, weight gain, and the risk of kidney stones. JAMA. 2005;293(4):455–62.
Taylor EN, Curhan GC. Body size and 24-hour urine composition. Am J Kidney Dis. [Research Support, N.I.H., Extramural]. 2006;48(6):905–15.
Torricelli FC, De S, Li I, Sarkissian C, Monga M. Can obese stone formers follow dietary recommendations? J Endourol. 2014;28(2):248–51.
Borghi L, Meschi T, Amato F, Briganti A, Novarini A, Giannini A. Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study. J Urol. [Clinical Trial Randomized Controlled Trial]. 1996;155(3):839–43.
Borghi L, Meschi T, Amato F, Novarini A, Romanelli A, Cigala F. Hot occupation and nephrolithiasis. J Urol. 1993;150(6):1757–60.
Fink HA, Akornor JW, Garimella PS, MacDonald R, Cutting A, Rutks IR, et al. Diet, fluid, or supplements for secondary prevention of nephrolithiasis: a systematic review and meta-analysis of randomized trials. Eur Urol. [Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov’t Research Support, U.S. Gov’t, Non-P.H.S. Review]. 2009;56(1):72–80.
Shuster J, Jenkins A, Logan C, Barnett T, Riehle R, Zackson D, et al. Soft drink consumption and urinary stone recurrence: a randomized prevention trial. J Clin Epidemiol. [Clinical Trial Randomized Controlled Trial Research Support, Non-U.S. Gov’t Research Support, U.S. Gov’t, P.H.S.]. 1992;45(8):911–6.
Abate N, Chandalia M, Cabo-Chan AV Jr, Moe OW, Sakhaee K. The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance. Kidney Int. [Research Support, U.S. Gov’t, Non-P.H.S. Research Support, U.S. Gov’t, P.H.S.]. 2004;65(2):386–92.
Sakhaee K, Adams-Huet B, Moe OW, Pak CY. Pathophysiologic basis for normouricosuric uric acid nephrolithiasis. Kidney Int. [Comparative Study Research Support, U.S. Gov’t, Non-P.H.S. Research Support, U.S. Gov’t, P.H.S.]. 2002;62(3):971–9.
Sakhaee K, Maalouf NM. Metabolic syndrome and uric acid nephrolithiasis. Semin Nephrol. [Research Support, N.I.H., Extramural Review]. 2008;28(2):174–80.
Siener R, Glatz S, Nicolay C, Hesse A. The role of overweight and obesity in calcium oxalate stone formation. Obes Res. 2004;12(1):106–13.
Grover PK, Marshall VR, Ryall RL. Dissolved urate salts out calcium oxalate in undiluted human urine in vitro: implications for calcium oxalate stone genesis. Chem Biol. 2003;10(3):271–8.
Rendina D, De Filippo G, Zampa G, Muscariello R, Mossetti G, Strazzullo P. Characteristic clinical and biochemical profile of recurrent calcium-oxalate nephrolithiasis in patients with metabolic syndrome. Nephrol Dial Transplant. 2011;26(7):2256–63.
Wrobel BM, Schubert G, Hormann M, Strohmaier WL. Overweight and obesity: risk factors in calcium oxalate stone disease? Adv Urol. 2012;2012:438707.
Lee SC, Kim YJ, Kim TH, Yun SJ, Lee NK, Kim WJ. Impact of obesity in patients with urolithiasis and its prognostic usefulness in stone recurrence. J Urol. [Research Support, Non-U.S. Gov’t]. 2008;179(2):570–4.
Shavit L, Ferraro PM, Johri N, Robertson W, Walsh SB, Moochhala S, et al. Effect of being overweight on urinary metabolic risk factors for kidney stone formation. Nephrol Dial Transplant. 2015;30(4):607–13.
Nouvenne A, Meschi T, Prati B, Guerra A, Allegri F, Vezzoli G, et al. Effects of a low-salt diet on idiopathic hypercalciuria in calcium-oxalate stone formers: a 3-mo randomized controlled trial. Am J Clin Nutr. [Randomized Controlled Trial Research Support, Non-U.S. Gov’t]. 2010;91(3):565–70.
Alberti KG, Zimmet P, Shaw J, et al. Lancet. [Research Support, Non-U.S. Gov’t]. 2005;366(9491):1059–62.
Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Curr Opin Cardiol. [Review]. 2006;21(1):1–6.
Wong YV, Cook P, Somani BK. The association of metabolic syndrome and urolithiasis. Int J Endocrinol Print. [Review]. 2015;2015:570674.
Kohjimoto Y, Sasaki Y, Iguchi M, Matsumura N, Inagaki T, Hara I. Association of metabolic syndrome traits and severity of kidney stones: results from a nationwide survey on urolithiasis in Japan. Am J Kidney Dis: Off J Nat Kidney Found. [Research Support, Non-U.S. Gov’t]. 2013;61(6):923–9.
West B, Luke A, Durazo-Arvizu RA, Cao G, Shoham D, Kramer H. Metabolic syndrome and self-reported history of kidney stones: the National Health and Nutrition Examination Survey (NHANES III) 1988–1994. Am J Kidney Dis: Off J Nat Kidney Found. 2008;51(5):741–7.
Curhan GC, Willett WC, Rimm EB, Stampfer MJ. A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med. [Research Support, Non-U.S. Gov’t Research Support, U.S. Gov’t, P.H.S.]. 1993;328(12):833–8.
Yun SJ, Ha YS, Kim WT, Kim YJ, Lee SC, Kim WJ. Sodium restriction as initial conservative treatment for urinary stone disease. J Urol. [Research Support, Non-U.S. Gov’t]. 2010;184(4):1372–6.
Weinberg AE, Patel CJ, Chertow GM, Leppert JT. Diabetic severity and risk of kidney stone disease. Eur Urol. 2014;65(1):242–7.
Kocvara R, Plasgura P, Petrik A, Louzensky G, Bartonickova K, Dvoracek J. A prospective study of nonmedical prophylaxis after a first kidney stone. BJU Int. [Clinical Trial Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov’t]. 1999;84(4):393–8.
Ortiz-Alvarado O, Miyaoka R, Kriedberg C, Moeding A, Stessman M, Anderson JK, et al. Impact of dietary counseling on urinary stone risk parameters in recurrent stone formers. J Endourol. 2011;25(3):535–40.
Escribano J, Balaguer A, Roque i Figuls M, Feliu A, Ferre N. Dietary interventions for preventing complications in idiopathic hypercalciuria. Cochrane Database Syst Rev. [Research Support, Non-U.S. Gov’t Review]. 2014;2:CD006022.
Wertheim ML, Nakada SY, Penniston KL. Current practice patterns of urologists providing nutrition recommendations to patients with kidney stones. J Endourol. 2014;28(9):1127–31.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this chapter
Cite this chapter
Rivera, M.E., Krambeck, A.E. (2018). Overweight/Obesity: Metabolic Benefits to Reduce Stone Risk. In: Lowry, P., Penniston, K. (eds) Nutrition Therapy for Urolithiasis. Springer, Cham. https://doi.org/10.1007/978-3-319-16414-4_12
Download citation
DOI: https://doi.org/10.1007/978-3-319-16414-4_12
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-16413-7
Online ISBN: 978-3-319-16414-4
eBook Packages: MedicineMedicine (R0)