Skip to main content

Device-Related Thrombi, Residual Leaks, and Consequences

  • Chapter
Left Atrial Appendage Closure

Part of the book series: Contemporary Cardiology ((CONCARD))

  • 973 Accesses

Abstract

The most common long-term complications with LAA closure comprise residual leaks and device-related thrombi. Data on these two complications are scarce, but diagnosis is important.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Reddy VY, Holmes D, Doshi SK, Neuzil P, Kar S. Safety of percutaneous left atrial appendage closure: results from the Watchman Left Atrial Appendage System for Embolic Protection in Patients with AF (PROTECT AF) clinical trial and the Continued Access Registry. Circulation. 2011;123:417–24.

    Article  PubMed  Google Scholar 

  2. Reddy VY, Mobius-Winkler S, Miller MA, Neuzil P, Schuler G, Wiebe J, Sick P, Sievert H. Left atrial appendage closure with the Watchman device in patients with a contraindication for oral anticoagulation: the ASAP study (ASA Plavix Feasibility Study with Watchman Left Atrial Appendage Closure Technology). J Am Coll Cardiol. 2013;61:2551–6.

    Article  PubMed  Google Scholar 

  3. Nietlispach F, Gloekler S, Krause R, Shakir S, Schmid M, Khattab AA, Wenaweser P, Windecker S, Meier B. Amplatzer left atrial appendage occlusion: single center 10-year experience. Catheter Cardiovasc Interv. 2013;82:283–9.

    Article  PubMed  Google Scholar 

  4. Katz ES, Tsiamtsiouris T, Applebaum RM, Schwartzbard A, Tunick PA, Kronzon I. Surgical left atrial appendage ligation is frequently incomplete: a transesophageal echocardiograhic study. J Am Coll Cardiol. 2000;36:468–71.

    Article  CAS  PubMed  Google Scholar 

  5. Kanderian AS, Gillinov AM, Pettersson GB, Blackstone E, Klein AL. Success of surgical left atrial appendage closure: assessment by transesophageal echocardiography. J Am Coll Cardiol. 2008;52:924–9.

    Article  PubMed  Google Scholar 

  6. Garcia-Fernandez MA, Perez-David E, Quiles J, Peralta J, Garcia-Rojas I, Bermejo J, Moreno M, Silva J. Role of left atrial appendage obliteration in stroke reduction in patients with mitral valve prosthesis: a transesophageal echocardiographic study. J Am Coll Cardiol. 2003;42:1253–8.

    Article  PubMed  Google Scholar 

  7. Tzikas A, Shakir S, Sievert H, Omran H, Berti S, Santoro G, Kefer J, Landmesser U, Nielsen-Kudsk JE, Cruz-Gonzalez I, Gafoor S, Tichelbacker T, Kanagaratnam P, Nietlispach F, Aminian A, Kasch F, Freixa X, Danna P, Rezzaghi M, Vermeersch P, Stock F, Stolcova M, Costa M, Ibrahim R, Schillinger W, Meier B, Park JW. Left atrial appendage occlusion for stroke prevention in atrial fibrillation: multicenter experience with the Amplatzer Cardiac Plug. Euro Interv. 2015;10:10.

    Google Scholar 

  8. Plicht B, Konorza TF, Kahlert P, Al-Rashid F, Kaelsch H, Janosi RA, Buck T, Bachmann HS, Siffert W, Heusch G, Erbel R. Risk factors for thrombus formation on the Amplatzer Cardiac Plug after left atrial appendage occlusion. JACC Cardiovasc Interv. 2013;6:606–13.

    Article  PubMed  Google Scholar 

  9. Viles-Gonzalez JF, Kar S, Douglas P, Dukkipati S, Feldman T, Horton R, Holmes D, Reddy VY. The clinical impact of incomplete left atrial appendage closure with the Watchman Device in patients with atrial fibrillation: a PROTECT AF (Percutaneous Closure of the Left Atrial Appendage Versus Warfarin Therapy for Prevention of Stroke in Patients with Atrial Fibrillation) substudy. J Am Coll Cardiol. 2012;59:923–9.

    Article  PubMed  Google Scholar 

  10. Bartus K, Han FT, Bednarek J, Myc J, Kapelak B, Sadowski J, Lelakowski J, Bartus S, Yakubov SJ, Lee RJ. Percutaneous left atrial appendage suture ligation using the LARIAT device in patients with atrial fibrillation: initial clinical experience. J Am Coll Cardiol. 2013;62:108–18.

    Article  PubMed  Google Scholar 

  11. Al-Khatib SM, Thomas L, Wallentin L, Lopes RD, Gersh B, Garcia D, Ezekowitz J, Alings M, Yang H, Alexander JH, Flaker G, Hanna M, Granger CB. Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial. Eur Heart J. 2013;34:2464–71.

    Article  CAS  PubMed  Google Scholar 

  12. Gloekler S, Shakir S, Doblies J, Khattab AA, Praz F, Guerios Ê, Koermendy D, Stortecky S, Pilgrim T, Buellesfeld L, Wenaweser P, Windecker S, Moschovitis A, Jaguszewski M, Landmesser U, Nietlispach F, Meier B. Early results of first versus second generation Amplatzer occluders for left atrial appendage closure in patients with atrial fibrillation. Clin Res Cardiol. 2015 Mar 4. [Epub ahead of print].

    Google Scholar 

  13. Nietlispach F, Krause R, Khattab A, Gloekler S, Schmid M, Wenaweser P, Windecker S, Meier B. Ad hoc percutaneous left atrial appendage closure. J Invasive Cardiol. 2013;25:683–6.

    PubMed  Google Scholar 

  14. Koermendy D, Nietlispach F, Shakir S, Gloekler S, Wenaweser P, Windecker S, Khattab AA, Meier B. Amplatzer left atrial appendage occlusion through a patent foramen ovale. Catheter Cardiovasc Interv. 2014;84(7):1190–6.

    Article  PubMed  Google Scholar 

  15. Cruz-Gonzalez I, Martin Moreiras J, Garcia E. Thrombus formation after left atrial appendage exclusion using an Amplatzer cardiac plug device. Catheter Cardiovasc Interv. 2011;78:970–3.

    Article  PubMed  Google Scholar 

  16. Guerios EE, Gloekler S, Schmid M, Khattab A, Nietlispach F, Meier B. Double device left atrial appendage closure. EuroIntervention. 2014. Jul 10. pii: 20130311-05. doi:10.4244/EIJY14M07_03. [Epub ahead of print].

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Fabian Nietlispach M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Nietlispach, F., Meier, B. (2016). Device-Related Thrombi, Residual Leaks, and Consequences. In: Saw, J., Kar, S., Price, M. (eds) Left Atrial Appendage Closure. Contemporary Cardiology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-16280-5_20

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-16280-5_20

  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-16279-9

  • Online ISBN: 978-3-319-16280-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics