Abstract
Embryo implantation is a complex process involving endocrine, paracrine, autocrine, and juxtacrine modulators that span cell–cell and cell–matrix interactions. The quality of implantation is predictive for pregnancy success. Earlier observational studies formed the basis for genetic and molecular approaches that ensued with emerging technological advances. However, the precise sequence and details of the molecular interactions involved have yet to be defined. This review reflects briefly on aspects of our current understanding of rodent implantation as a tribute to Roger Short’s lifelong contributions to the field of reproductive physiology.
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Acknowledgments
We thank Serenity Curtis for her help in editing this review article. The work described from Dey lab has been funded by NIH. We regret that space limitations precluded us from citing many relevant references.
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Cha, J.M., Dey, S.K. (2015). Reflections on Rodent Implantation. In: Geisert, R., Bazer, F. (eds) Regulation of Implantation and Establishment of Pregnancy in Mammals. Advances in Anatomy, Embryology and Cell Biology, vol 216. Springer, Cham. https://doi.org/10.1007/978-3-319-15856-3_5
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